stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

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What functions are associated with stearic acid?


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What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

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What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Zhang JW et al. [Studies on the chemical constituents of Toricellia angulata var. intermedia]. 2010 Zhong Yao Cai pmid:21434432
Fang X et al. Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. 2010 BMC Syst Biol pmid:21092312
Daraghmeh N et al. Preparation and characterization of a novel co-processed excipient of chitin and crystalline mannitol. 2010 AAPS PharmSciTech pmid:21052880
Legrand P and Rioux V The complex and important cellular and metabolic functions of saturated fatty acids. 2010 Lipids pmid:20625935
Hodson L et al. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20628024
Liu TY and Lin YL Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs. 2010 Acta Biomater pmid:19819354
Jeevanandham S et al. Sustain-release of various drugs from leucaena leucocephala polysaccharide. 2010 J Young Pharm pmid:21331185
Kiss H et al. Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). 2010 Stand Genomic Sci pmid:21304711
Nouri A et al. Effect of process control agent on the porous structure and mechanical properties of a biomedical Ti-Sn-Nb alloy produced by powder metallurgy. 2010 Acta Biomater pmid:19815096
Liu RS and Tang YJ Quantitative analysis for the effect of plant oil and fatty acid on Tuber melanosporum culture by uniform design combined with partial least squares regression. 2010 Appl. Microbiol. Biotechnol. pmid:20473608
Sorek N et al. An S-acylation switch of conserved G domain cysteines is required for polarity signaling by ROP GTPases. 2010 Curr. Biol. pmid:20451389
Murate M et al. Phosphatidylglucoside forms specific lipid domains on the outer leaflet of the plasma membrane. 2010 Biochemistry pmid:20433166
Sun H et al. Complete genome sequence of Desulfarculus baarsii type strain (2st14). 2010 Stand Genomic Sci pmid:21304732
Pennick G et al. Superior effect of isostearyl isostearate on improvement in stratum corneum water permeability barrier function as examined by the plastic occlusion stress test. 2010 Int J Cosmet Sci pmid:20642769
Kajiro H et al. Flexible two-dimensional square-grid coordination polymers: structures and functions. 2010 Int J Mol Sci pmid:21152303
Coulon C et al. Chemical analysis of cellular and extracellular carbohydrates of a biofilm-forming strain Pseudomonas aeruginosa PA14. 2010 PLoS ONE pmid:21151973
Wieder DR and Pattimakiel L Examining the efficacy, safety, and patient acceptability of the combined contraceptive vaginal ring (NuvaRing). 2010 Int J Womens Health pmid:21151688
Kanjanavas P et al. Purification and characterization of organic solvent and detergent tolerant lipase from thermotolerant Bacillus sp. RN2. 2010 Int J Mol Sci pmid:21152301
Yang X et al. In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. 2010 Drug Dev Ind Pharm pmid:20141448
Du YZ et al. Stearic acid grafted chitosan oligosaccharide micelle as a promising vector for gene delivery system: factors affecting the complexation. 2010 Int J Pharm pmid:20170716
Baki G et al. Role of surface free energy and spreading coefficient in the formulation of active agent-layered pellets. 2010 Eur J Pharm Biopharm pmid:19931611
Bolton B and Halpern BP Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. 2010 Chem. Senses pmid:20100787
Lu L et al. Near infrared spectroscopy of stearic acid adsorbed on montmorillonite. 2010 Spectrochim Acta A Mol Biomol Spectrosc pmid:20071218
Roblegg E et al. Development of lipophilic calcium stearate pellets using ibuprofen as model drug. 2010 Eur J Pharm Biopharm pmid:20080179
Gentile CL et al. Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin. 2010 Mol. Cell. Biochem. pmid:20607591
Bele MH et al. Effect of Flow Aids on Mucoadhesive Properties of Polymeric Discs of Polyoxyethylene and Carbopol 971P. 2010 Indian J Pharm Sci pmid:20582205
Rao KS and Srinivas K RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form. 2010 Indian J Pharm Sci pmid:20582199
Keny RV et al. Formulation and evaluation of rizatriptan benzoate mouth disintegrating tablets. 2010 Indian J Pharm Sci pmid:20582194
Eftaiha AF et al. Bioadhesive controlled metronidazole release matrix based on chitosan and xanthan gum. 2010 Mar Drugs pmid:20559494
Normand-Lauzière F et al. Increased postprandial nonesterified fatty acid appearance and oxidation in type 2 diabetes is not fully established in offspring of diabetic subjects. 2010 PLoS ONE pmid:20532041
Li LO et al. Early hepatic insulin resistance in mice: a metabolomics analysis. 2010 Mol. Endocrinol. pmid:20150186
Horne I et al. Two conserved Z9-octadecanoic acid desaturases in the red flour beetle, Tribolium castaneum. 2010 Gene pmid:20709164
Vlachou M et al. Utilization of hydrophilic swellable polymers as carriers for sustained drug delivery from matrices and three layer tablet systems. 2010 Curr Drug Deliv pmid:20695845
Walker S et al. Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery. 2010 Mol. Pharm. pmid:20669974
Saravanakumari P and Mani K Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. 2010 Bioresour. Technol. pmid:20637606
Invernizzi G et al. Sustained upregulation of stearoyl-CoA desaturase in bovine mammary tissue with contrasting changes in milk fat synthesis and lipogenic gene networks caused by lipid supplements. 2010 Funct. Integr. Genomics pmid:20607344
Chon B et al. Shell and ligand-dependent blinking of CdSe-based core/shell nanocrystals. 2010 Phys Chem Chem Phys pmid:20607188
Mathew M et al. Elevated plasma free fatty acids increase cardiovascular risk by inducing plasma biomarkers of endothelial activation, myeloperoxidase and PAI-1 in healthy subjects. 2010 Cardiovasc Diabetol pmid:20158910
Bunn RC et al. Palmitate and insulin synergistically induce IL-6 expression in human monocytes. 2010 Cardiovasc Diabetol pmid:21054880
Zhang LJ et al. Hot-injection synthesis of highly luminescent and monodisperse CdS nanocrystals using thioacetamide and cadmium source with proper reactivity. 2010 J Colloid Interface Sci pmid:19932894
Yoo HJ and HÃ¥kansson K Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. 2010 Anal. Chem. pmid:20704384
Balani PN et al. Influence of excipients in comilling on mitigating milling-induced amorphization or structural disorder of crystalline pharmaceutical actives. 2010 J Pharm Sci pmid:19902526
Yuan Y et al. A signal-on electrochemical probe-label-free aptasensor using gold-platinum alloy and stearic acid as enhancers. 2010 Biosens Bioelectron pmid:20708400
Jun HY et al. Long residence time of ultrasound microbubbles targeted to integrin in murine tumor model. 2010 Acad Radiol pmid:19815430
Jian WX et al. [Detection and analysis on plasma metabolomics in patient with coronary heart disease of Xin-blood stasis syndrome pattern]. 2010 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:20815270
Lai TY et al. Alterations in serum fatty acid concentrations and desaturase activities in Bietti crystalline dystrophy unaffected by CYP4V2 genotypes. 2010 Invest. Ophthalmol. Vis. Sci. pmid:19797200
Gonzalez-Mira E et al. Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC. 2010 Colloids Surf B Biointerfaces pmid:20719479
Chakraborty S et al. Utilization of adsorption technique in the development of oral delivery system of lipid based nanoparticles. 2010 Colloids Surf B Biointerfaces pmid:20728320
Valencia-Chamorro SA et al. Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins. 2010 J. Food Sci. pmid:21535515
Alloatti A et al. Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. 2010 PLoS ONE pmid:21151902