stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypopituitarism D007018 7 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Hypothyroidism D007037 32 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Infertility D007246 3 associated lipids
Insulin Resistance D007333 99 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
MORRIS LJ SEPARATION OF ISOMERIC LONG-CHAIN POLYHYDROXY ACIDS BY THIN-LAYER CHROMATOGRAPHY. 1963 J. Chromatogr. pmid:14070998
SOLOFF LA and WIEDEMAN MP BIOMICROSCOPIC OBSERVATIONS ON VASOCONSTRICTIVE AND THROMBOGENIC EFFECTS PRODUCED BY LONG-CHAIN SATURATED FATTY ACIDS WITHIN THE VASCULATURE OF THE WING OF AN UNANAESTHETIZED BAT. 1963 Nature pmid:14058613
ROUS S and FAVARGER P [ROLE OF DEGRADATION IN THE MAINTENANCE OF THE COMPOSITION OF RESERVE FATTY ACIDS]. 1963 Helv Physiol Pharmacol Acta pmid:14058926
GOMPERTZ SM and SAMMONS HG THE ORIGIN OF FAECAL LIPIDS. THE COMPOSITION OF FAECAL FATSIN HUMAN SUBJECTS. 1963 Clin. Chim. Acta pmid:14063975
DEMPSKI RE et al. Permeability of excised human keratin to lipid-soluble substances. II. 1963 J Pharm Sci pmid:14026933
KAUNITZ H et al. Studies of the generalized Shwartzman reaction produced by diet. IV. Ethyl ester fractions of cod liver oil and dihydroxystearic acid. 1963 Metab. Clin. Exp. pmid:14031428
HALL PF et al. Synthesis of fatty acids by testicular tissue in vitro. 1963 Can J Biochem Physiol pmid:13952129
HUEPER WC and PAYNE WW Polyoxyethylene(8)stearate. Carcinogenic studies. 1963 Arch. Environ. Health pmid:13955486
HIRSCH J FACTICE CHROMATOGRAPHY: AN AUTOMATICALLY MONITORED, LIQUID-GEL SYSTEM FOR THE SEPARATION OF NONPOLAR LIPIDS. 1963 J. Lipid Res. pmid:14167659
CALI G et al. [GAS CHROMATOGRAPHY RESEARCH ON THE FATTY ACIDS OF HUMAN ADIPOSE TISSUE]. 1963 Ric Sci 2 Ser Pt 2 Rend B pmid:14123061