| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Hypopituitarism | D007018 | 7 associated lipids |
| Hypothalamic Diseases | D007027 | 3 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| DEYKIN D and GOODMAN DS | The hydrolysis of long-chain fatty acid esters of cholesterol with rat liver enzymes. | 1962 | J. Biol. Chem. | pmid:14027461 |
| TROUT DL and ESTES EH | Factors affecting liver uptake of serum free stearic acid-1-C14. | 1962 | Am. J. Physiol. | pmid:13994303 |
| WALLEN LL et al. | The microbiological production of 10-hydroxystearic acid from oleic acid. | 1962 | Arch. Biochem. Biophys. | pmid:13998583 |
| FOSSA T | [Inhibition of hepatic glucose-6-phosphatase by fatty acids and zinc ions]. | 1962 | Boll. Soc. Ital. Biol. Sper. | pmid:13958874 |
| BARGONI N and SISINI A | [Inhibition and reactivation of the hydrolases of digestion]. | 1962 | Boll. Soc. Ital. Biol. Sper. | pmid:13966663 |
| FOTI L et al. | [In vitro liver biosynthesis of cholesterol from acetate, stearate and linoleate 1-C-14]. | 1961 | Boll. Soc. Ital. Biol. Sper. | pmid:13958917 |
| AGARWAL SC et al. | Blood-level duration limit test of procaine benzylpenicillin in sheep. | 1961 | Bull. World Health Organ. | pmid:13859560 |
| LIN TM et al. | Effect of stearic acid and cholesterol on biosynthesis of sterol by the chicken liver. | 1960 | Am. J. Physiol. | pmid:14417022 |
| SHANES AM and GERSHFELD NL | Interactions of veratrum alkaloids, procaine, and calcium with monolayers of stearic acid and their implications for pharmacological action. | 1960 | J. Gen. Physiol. | pmid:13750673 |
| BLOMSTRAND R et al. | Asymmetric incorporation of linoleic acid-1-C14 and stearic acid-1-C14 into human lymph lecithins during fat absorption. | 1959 | Proc. Soc. Exp. Biol. Med. | pmid:13645714 |