stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypopituitarism D007018 7 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Hypothyroidism D007037 32 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Infertility D007246 3 associated lipids
Insulin Resistance D007333 99 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Di Vaio C et al. Influence of some environmental factors on drupe maturation and olive oil composition. 2013 J. Sci. Food Agric. pmid:22936522
Ruddle P et al. Effect of a novel mutation in a Δ9-stearoyl-ACP-desaturase on soybean seed oil composition. 2013 Theor. Appl. Genet. pmid:22961205
Němcová-Fürstová V et al. Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells. 2013 Cell. Physiol. Biochem. pmid:23466956
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Gotoh K et al. Evaluation of removal of model particulate and oily soils from poly(ethylene terephthalate) films by microscopic image analysis. 2013 J Oleo Sci pmid:23391530
Ogata F et al. Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). 2013 J Oleo Sci pmid:23391535
Ishida Y et al. Fatty acid solubilizer from the oral disk of the blowfly. 2013 PLoS ONE pmid:23326317
John CT et al. Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate. 2013 Pharm. Res. pmid:23512680
Stank K and Steckel H Physico-chemical characterisation of surface modified particles for inhalation. 2013 Int J Pharm pmid:23518364
Kumar N et al. Salt dependent stability of stearic acid Langmuir-Blodgett films exposed to aqueous electrolytes. 2013 Langmuir pmid:23565719
Han SH et al. Bioinspired self-assembled peptide nanofibers with thermostable multivalent α-helices. 2013 Biomacromolecules pmid:23550841
Jin Q et al. A novel cationic microbubble coated with stearic acid-modified polyethylenimine to enhance DNA loading and gene delivery by ultrasound. 2013 PLoS ONE pmid:24086748
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Shibata E et al. Free fatty acids inhibit protein tyrosine phosphatase 1B and activate Akt. 2013 Cell. Physiol. Biochem. pmid:24107614
Michailidou VN et al. Anisotropic diffusion of concentrated hard-sphere colloids near a hard wall studied by evanescent wave dynamic light scattering. 2013 J Chem Phys pmid:24182077
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Neupane YR et al. Lipid drug conjugate nanoparticle as a novel lipid nanocarrier for the oral delivery of decitabine: ex vivo gut permeation studies. 2013 Nanotechnology pmid:24061410
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Hentzschel CM et al. Comparison of traditional and novel tableting excipients: physical and compaction properties. 2012 Nov-Dec Pharm Dev Technol pmid:21740091
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Pujeri SS et al. Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. 2012 Jan-Mar Sci Pharm pmid:22396908
Stinton LM and Shaffer EA Epidemiology of gallbladder disease: cholelithiasis and cancer. 2012 Gut Liver pmid:22570746
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Sharma A and Chauhan RS In silico identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants. 2012 Comp. Funct. Genomics pmid:22312320
Patel K et al. Duloxetine HCl lipid nanoparticles: preparation, characterization, and dosage form design. 2012 AAPS PharmSciTech pmid:22167415
Zhang J et al. Synthesis of NaYF(4):Yb/Er/Gd up-conversion luminescent nanoparticles and luminescence resonance energy transfer-based protein detection. 2012 Anal. Biochem. pmid:22155069
Wajid NA and Halpern BP Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. 2012 Chem. Senses pmid:22459162
Gröblacher B et al. Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis. 2012 Bioorg. Med. Chem. pmid:22459211
Nakagawa H et al. Evaluation of infrared-reflection absorption spectroscopy measurement and locally weighted partial least-squares for rapid analysis of residual drug substances in cleaning processes. 2012 Anal. Chem. pmid:22449097
Ménard N et al. Novel surfactants with diglutamic acid polar head group: drug solubilization and toxicity studies. 2012 Pharm. Res. pmid:22451248
Hu SY et al. [Studies on sustained release solid dispersion of tripterine carried by HPMC-stearic acid]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23311152
Gellrich V et al. Behavior of perfluorinated compounds in soils during leaching experiments. 2012 Chemosphere pmid:22391048
Muro M et al. Molecular rearrangement in a zinc stearate Langmuir film dependent on a film preparation method studied using polarization-modulation infrared reflection absorption spectroscopy and X-ray absorption fine structure. 2012 J Phys Chem B pmid:22339471
Okoye P et al. To evaluate the effect of various magnesium stearate polymorphs using powder rheology and thermal analysis. 2012 Drug Dev Ind Pharm pmid:22304483
Wulff-Pérez M et al. Controlling lipolysis through steric surfactants: new insights on the controlled degradation of submicron emulsions after oral and intravenous administration. 2012 Int J Pharm pmid:22209995
Simonsen ME et al. Comparison of methods for evaluation of activity of photocatalytic films. 2012 Environ Sci Pollut Res Int pmid:23054739
Yuan H et al. Preparation and evaluation of SiO2-deposited stearic acid-g-chitosan nanoparticles for doxorubicin delivery. 2012 Int J Nanomedicine pmid:23055724
Dawes J et al. An investigation into the impact of magnesium stearate on powder feeding during roller compaction. 2012 Drug Dev Ind Pharm pmid:21810064
Guo C et al. In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. 2012 J Nanosci Nanotechnol pmid:22523972
Polizzotti BD et al. Intrapericardial delivery of gelfoam enables the targeted delivery of Periostin peptide after myocardial infarction by inducing fibrin clot formation. 2012 PLoS ONE pmid:22590609
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