| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Seizures | D012640 | 87 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Horio T et al. | Measurement of flowability of lubricated powders by the vibrating tube method. | 2013 | Drug Dev Ind Pharm | pmid:22781029 |
| Mazel V et al. | The surface layer of pharmaceutical compacts: the role of the punch surface and its impact on the mechanical properties of the compacts. | 2013 | Int J Pharm | pmid:22902389 |
| Intorre F et al. | Fatty acid content of serum lipid fractions and blood lipids in normolipidaemic volunteers fed two types of cheese having different fat compositions: a pilot study. | 2013 | Int J Food Sci Nutr | pmid:22849318 |
| Salehi M et al. | Debinding mechanisms in thermoplastic processing of a Ba(0.5)Sr(0.5)Co(0.8)Fe(0.2)O(3-δ)- stearic acid-polystyrene mixture. | 2013 | ChemSusChem | pmid:23281298 |
| He M et al. | Controllable stearic acid crystal induced high hydrophobicity on cellulose film surface. | 2013 | ACS Appl Mater Interfaces | pmid:23289586 |
| Wan Q et al. | Self-assembled magnetic theranostic nanoparticles for highly sensitive MRI of minicircle DNA delivery. | 2013 | Nanoscale | pmid:23224057 |
| Dhasaiyan P et al. | Influence of the sophorolipid molecular geometry on their self-assembled structures. | 2013 | Chem Asian J | pmid:23208802 |
| Baek JS and Cho CW | 2-Hydroxypropyl-β-cyclodextrin-modified SLN of paclitaxel for overcoming p-glycoprotein function in multidrug-resistant breast cancer cells. | 2013 | J. Pharm. Pharmacol. | pmid:23215690 |
| Salazar J et al. | Application of the combinative particle size reduction technology H 42 to produce fast dissolving glibenclamide tablets. | 2013 | Eur J Pharm Sci | pmid:23587645 |
| Mérian J et al. | Synthetic lipid nanoparticles targeting steroid organs. | 2013 | J. Nucl. Med. | pmid:24071507 |
| Liu Z et al. | Changes in the electron paramagnetic resonance spectra of albumin-associated spin-labeled stearic acid as a diagnostic parameter of colorectal cancer. | 2013 | World J Surg Oncol | pmid:24025321 |
| Osorio JG and Muzzio FJ | Effects of powder flow properties on capsule filling weight uniformity. | 2013 | Drug Dev Ind Pharm | pmid:23902366 |
| Vadakkan MV et al. | Dry powder cationic lipopolymeric nanomicelle inhalation for targeted delivery of antitubercular drug to alveolar macrophage. | 2013 | Int J Nanomedicine | pmid:23990716 |
| Asumadu-Mensah A et al. | Solid lipid dispersions: potential delivery system for functional ingredients in foods. | 2013 | J. Food Sci. | pmid:23865449 |
| Hagen RM et al. | Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent. | 2013 | Anticancer Res. | pmid:24123008 |
| Yuan B et al. | Laboratory-scale column study for remediation of TCE-contaminated aquifers using three-section controlled-release potassium permanganate barriers. | 2013 | J Environ Sci (China) | pmid:24218827 |
| Pan S et al. | Particle formation by supercritical fluid extraction and expansion process. | 2013 | ScientificWorldJournal | pmid:24223031 |
| Li P et al. | Effect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro. | 2013 | Cell. Physiol. Biochem. | pmid:24335176 |
| Tammaro A et al. | Magnesium stearate: an underestimated allergen. | 2012 Oct-Dec | J. Biol. Regul. Homeost. Agents | pmid:23241129 |
| Hentzschel CM et al. | Comparison of traditional and novel tableting excipients: physical and compaction properties. | 2012 Nov-Dec | Pharm Dev Technol | pmid:21740091 |
| Khan FN and Dehghan MH | Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. | 2012 Jan-Mar | Sci Pharm | pmid:22396916 |
| Pujeri SS et al. | Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. | 2012 Jan-Mar | Sci Pharm | pmid:22396908 |
| Stinton LM and Shaffer EA | Epidemiology of gallbladder disease: cholelithiasis and cancer. | 2012 | Gut Liver | pmid:22570746 |
| Vinay KB et al. | Spectrophotometric Determination of Mycophenolate Mofetil as Its Charge-Transfer Complexes with Two π-Acceptors. | 2012 | J Anal Methods Chem | pmid:22567572 |
| Prashanth KN and Basavaiah K | Sensitive spectrophotometric determination of atenolol in pharmaceutical formulations using bromate-bromide mixture as an eco-friendly brominating agent. | 2012 | J Anal Methods Chem | pmid:22567567 |
| de Souza Monteiro A et al. | Bioconversion of biodiesel refinery waste in the bioemulsifier by Trichosporon mycotoxinivorans CLA2. | 2012 | Biotechnol Biofuels | pmid:22559210 |
| Ahn BJ et al. | Solvent-free acid-catalyzed ring-opening of epoxidized oleochemicals using stearates/stearic acid, and its applications. | 2012 | J. Agric. Food Chem. | pmid:22304525 |
| Li D et al. | Ruminal microbe of biohydrogenation of trans-vaccenic acid to stearic acid in vitro. | 2012 | BMC Res Notes | pmid:22336099 |
| Aling J and Podczeck F | The filling of powdered herbs into two-piece hard capsules using hydrogenated cotton seed oil as lubricant. | 2012 | Eur J Pharm Sci | pmid:22960627 |
| Visioli F et al. | Molecular targets of omega 3 and conjugated linoleic Fatty acids - "micromanaging" cellular response. | 2012 | Front Physiol | pmid:22393325 |
| Qu J et al. | Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. | 2012 | Biotechnol Biofuels | pmid:22377043 |
| Kottala N et al. | Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets. | 2012 | AAPS PharmSciTech | pmid:22965660 |
| Som I et al. | Status of surfactants as penetration enhancers in transdermal drug delivery. | 2012 | J Pharm Bioallied Sci | pmid:22368393 |
| Al-Ghamdi AF et al. | Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids. | 2012 | Chem Cent J | pmid:22353684 |
| Wolańska D and Kłosiewicz-Latoszek L | [Fatty acids intake and serum lipids profile in overweighted and obese adults]. | 2012 | Rocz Panstw Zakl Hig | pmid:22928362 |
| Walash MI et al. | Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma. | 2012 | Chem Cent J | pmid:22333299 |
| Craig OE et al. | Distinguishing wild ruminant lipids by gas chromatography/combustion/isotope ratio mass spectrometry. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22956328 |
| Ahn J et al. | Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet. | 2012 | Mol Nutr Food Res | pmid:22968990 |
| Darwish IA et al. | Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate. | 2012 | Chem Cent J | pmid:22305461 |
| Quintela M et al. | Estimation of the uncertainty associated with the results based on the validation of chromatographic analysis procedures: application to the determination of chlorides by high performance liquid chromatography and of fatty acids by high resolution gas chromatography. | 2012 | J Chromatogr A | pmid:22227361 |
| Gabirot M et al. | Differences in Chemical Sexual Signals May Promote Reproductive Isolation and Cryptic Speciation between Iberian Wall Lizard Populations. | 2012 | Int J Evol Biol | pmid:22288019 |
| Kim S et al. | Lipid-binding properties of TRIM72. | 2012 | BMB Rep | pmid:22281009 |
| Ghanam RH et al. | Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly. | 2012 | Front Microbiol | pmid:22363329 |
| Rozema E et al. | Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds. | 2012 | Evid Based Complement Alternat Med | pmid:22675394 |
| Sharma A and Chauhan RS | In silico identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants. | 2012 | Comp. Funct. Genomics | pmid:22312320 |
| El Semary NA | The antimicrobial profile of extracts of a Phormidium-like cyanobacterium changes with phosphate levels. | 2012 | World J. Microbiol. Biotechnol. | pmid:22806854 |
| Yee JK et al. | Subcutaneous adipose tissue fatty acid desaturation in adults with and without rare adipose disorders. | 2012 | Lipids Health Dis | pmid:22300160 |
| Patel K et al. | Duloxetine HCl lipid nanoparticles: preparation, characterization, and dosage form design. | 2012 | AAPS PharmSciTech | pmid:22167415 |
| Busignies V et al. | Prediction of the compressibility of complex mixtures of pharmaceutical powders. | 2012 | Int J Pharm | pmid:22759643 |
| Jubie S et al. | Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. | 2012 | Eur J Med Chem | pmid:22770606 |
| Zhang J et al. | Synthesis of NaYF(4):Yb/Er/Gd up-conversion luminescent nanoparticles and luminescence resonance energy transfer-based protein detection. | 2012 | Anal. Biochem. | pmid:22155069 |
| Krogager TP et al. | Identification of a potential biomarker panel for the intake of the common dietary trans fat elaidic acid (trans∆9-C18:1). | 2012 | J Proteomics | pmid:22483997 |
| Pawar AA et al. | Influence of precursor solvent properties on matrix crystallinity and drug release rates from nanoparticle aerosol lipid matrices. | 2012 | Int J Pharm | pmid:22469694 |
| Zhu S et al. | Lysosomal delivery of a lipophilic gemcitabine prodrug using novel acid-sensitive micelles improved its antitumor activity. | 2012 | Bioconjug. Chem. | pmid:22471294 |
| Streit MR et al. | High survival in young patients using a second generation uncemented total hip replacement. | 2012 | Int Orthop | pmid:22113735 |
| Wajid NA and Halpern BP | Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. | 2012 | Chem. Senses | pmid:22459162 |
| Gröblacher B et al. | Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis. | 2012 | Bioorg. Med. Chem. | pmid:22459211 |
| Nakagawa H et al. | Evaluation of infrared-reflection absorption spectroscopy measurement and locally weighted partial least-squares for rapid analysis of residual drug substances in cleaning processes. | 2012 | Anal. Chem. | pmid:22449097 |
| Ménard N et al. | Novel surfactants with diglutamic acid polar head group: drug solubilization and toxicity studies. | 2012 | Pharm. Res. | pmid:22451248 |
| Taveira SF et al. | Development of cationic solid lipid nanoparticles with factorial design-based studies for topical administration of doxorubicin. | 2012 | J Biomed Nanotechnol | pmid:22515073 |
| Imarisio C et al. | Adenosine A(2a) receptor stimulation prevents hepatocyte lipotoxicity and non-alcoholic steatohepatitis (NASH) in rats. | 2012 | Clin. Sci. | pmid:22439844 |
| Rojas J and Kumar V | Effect of silicification on the tableting performance of cellulose ii: a novel multifunctional excipient. | 2012 | Chem. Pharm. Bull. | pmid:22689398 |
| Griffith EC et al. | Hydrophobic collapse of a stearic acid film by adsorbed l-phenylalanine at the air-water interface. | 2012 | J Phys Chem B | pmid:22691061 |
| Tumen I et al. | A therapeutic approach for wound healing by using essential oils of cupressus and juniperus species growing in Turkey. | 2012 | Evid Based Complement Alternat Med | pmid:21941588 |
| de Bari O et al. | Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic Fatty liver disease. | 2012 | J Lipids | pmid:22132342 |
| Zeng XJ et al. | [Chemical constituents of Berchemia lineate]. | 2012 | Zhong Yao Cai | pmid:22822666 |
| Hu FQ et al. | pH triggered doxorubicin delivery of PEGylated glycolipid conjugate micelles for tumor targeting therapy. | 2012 | Mol. Pharm. | pmid:22827551 |
| Sellami M et al. | Enzymatic transesterification of palm stearin and olein blends to produce zero-trans margarine fat. | 2012 | BMC Biotechnol. | pmid:22889174 |
| Li Y et al. | New bactericidal surgical suture coating. | 2012 | Langmuir | pmid:22877364 |
| Das SC and Stewart PJ | Characterising surface energy of pharmaceutical powders by inverse gas chromatography at finite dilution. | 2012 | J. Pharm. Pharmacol. | pmid:22881445 |
| Wang YN et al. | [Study on chemical constituents from Anoectochilus chapaensis]. | 2012 | Zhong Yao Cai | pmid:23236826 |
| Hu SY et al. | [Studies on sustained release solid dispersion of tripterine carried by HPMC-stearic acid]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23311152 |
| Yavuz B et al. | An overview on dry eye treatment: approaches for cyclosporin a delivery. | 2012 | ScientificWorldJournal | pmid:22619624 |
| Guzzi R et al. | Dynamics and binding affinity of spin-labeled stearic acids in β-lactoglobulin: evidences from EPR spectroscopy and molecular dynamics simulation. | 2012 | J Phys Chem B | pmid:22950964 |
| de Jong S et al. | A semipermanent coating for preventing protein adsorption at physiological pH in kinetic capillary electrophoresis. | 2012 | Electrophoresis | pmid:22899267 |
| Dziewulska A et al. | Monounsaturated fatty acids are required for membrane translocation of protein kinase C-theta induced by lipid overload in skeletal muscle. | 2012 | Mol. Membr. Biol. | pmid:22881371 |
| Zhang WY et al. | Chronic unpredictable mild stress affects myocardial metabolic profiling of SD rats. | 2012 | J Pharm Biomed Anal | pmid:22658902 |
| Tuli RA et al. | Studies on the effect of the size of polycaprolactone microspheres for the dispersion of salbutamol sulfate from dry powder inhaler formulations. | 2012 | Pharm. Res. | pmid:22584947 |
| Itoh Y and Hasegawa T | Polarization dependence of Raman scattering from a thin film involving optical anisotropy theorized for molecular orientation analysis. | 2012 | J Phys Chem A | pmid:22551093 |
| Gellrich V et al. | Behavior of perfluorinated compounds in soils during leaching experiments. | 2012 | Chemosphere | pmid:22391048 |
| Muro M et al. | Molecular rearrangement in a zinc stearate Langmuir film dependent on a film preparation method studied using polarization-modulation infrared reflection absorption spectroscopy and X-ray absorption fine structure. | 2012 | J Phys Chem B | pmid:22339471 |
| Okoye P et al. | To evaluate the effect of various magnesium stearate polymorphs using powder rheology and thermal analysis. | 2012 | Drug Dev Ind Pharm | pmid:22304483 |
| Wulff-Pérez M et al. | Controlling lipolysis through steric surfactants: new insights on the controlled degradation of submicron emulsions after oral and intravenous administration. | 2012 | Int J Pharm | pmid:22209995 |
| Simmons DM and Gierer DS | A material sparing test to predict punch sticking during formulation development. | 2012 | Drug Dev Ind Pharm | pmid:22181042 |
| Simonsen ME et al. | Comparison of methods for evaluation of activity of photocatalytic films. | 2012 | Environ Sci Pollut Res Int | pmid:23054739 |
| Yuan H et al. | Preparation and evaluation of SiO2-deposited stearic acid-g-chitosan nanoparticles for doxorubicin delivery. | 2012 | Int J Nanomedicine | pmid:23055724 |
| Mai K et al. | Rosiglitazone increases fatty acid Δ9-desaturation and decreases elongase activity index in human skeletal muscle in vivo. | 2012 | Metab. Clin. Exp. | pmid:21741058 |
| Dobrzyn P et al. | Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation. | 2012 | Mitochondrion | pmid:21664496 |
| Gören AC et al. | Fatty acid composition and chemotaxonomic evaluation of species of Stachys. | 2012 | Nat. Prod. Res. | pmid:21859257 |
| Dawes J et al. | An investigation into the impact of magnesium stearate on powder feeding during roller compaction. | 2012 | Drug Dev Ind Pharm | pmid:21810064 |
| Guo C et al. | In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. | 2012 | J Nanosci Nanotechnol | pmid:22523972 |
| Bederman I et al. | Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22679004 |
| Meka VS et al. | Design and in vitro evaluation of effervescent gastric floating drug delivery systems of propanolol HCl. | 2012 | Invest Clin | pmid:22524109 |
| Lalloo AK et al. | Decoupling the role of image size and calorie intake on gastric retention of swelling-based gastric retentive formulations: pre-screening in the dog model. | 2012 | Int J Pharm | pmid:22546295 |
| Bevilacqua A et al. | Selection of Yeasts as Starter Cultures for Table Olives: A Step-by-Step Procedure. | 2012 | Front Microbiol | pmid:22666220 |
| Shah KU and Khan GM | Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. | 2012 | ScientificWorldJournal | pmid:22649325 |
| Polizzotti BD et al. | Intrapericardial delivery of gelfoam enables the targeted delivery of Periostin peptide after myocardial infarction by inducing fibrin clot formation. | 2012 | PLoS ONE | pmid:22590609 |
| Song IS et al. | Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition. | 2012 | PLoS ONE | pmid:22590580 |
| Ahmed TA et al. | Miconazole nitrate oral disintegrating tablets: in vivo performance and stability study. | 2012 | AAPS PharmSciTech | pmid:22585373 |
| Varshosaz J et al. | Development and evaluation of a novel pellet-based tablet system for potential colon delivery of budesonide. | 2012 | J Drug Deliv | pmid:22577558 |