| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Seizures | D012640 | 87 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chu X et al. | Sterol regulatory element-binding protein-1c mediates increase of postprandial stearic acid, a potential target for improving insulin resistance, in hyperlipidemia. | 2013 | Diabetes | pmid:22966071 |
| Hu FQ et al. | Effective antitumor gene therapy delivered by polyethylenimine-conjugated stearic acid-g-chitosan oligosaccharide micelles. | 2013 | Gene Ther. | pmid:22951455 |
| Sovány T et al. | Application of physicochemical properties and process parameters in the development of a neural network model for prediction of tablet characteristics. | 2013 | AAPS PharmSciTech | pmid:23413109 |
| Mirani ZA and Jamil N | Role of extra-cellular fatty acids in vancomycin induced biofilm formation by vancomycin resistant Staphylococcus aureus. | 2013 | Pak J Pharm Sci | pmid:23455211 |
| Vervaeck A et al. | Prilling of fatty acids as a continuous process for the development of controlled release multiparticulate dosage forms. | 2013 | Eur J Pharm Biopharm | pmid:23474381 |
| Risley DS et al. | Analysis of magnesium from magnesium stearate in pharmaceutical tablet formulations using hydrophilic interaction liquid chromatography with nano quantity analyte detection. | 2013 | J Pharm Biomed Anal | pmid:23474810 |
| Zamora-Rojas E et al. | Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. | 2013 | Meat Sci. | pmid:23793086 |
| Song W et al. | Importance of size and distribution of Ni nanoparticles for the hydrodeoxygenation of microalgae oil. | 2013 | Chemistry | pmid:23794421 |
| Sharma P et al. | Structural insights into the dual strategy of recognition by peptidoglycan recognition protein, PGRP-S: structure of the ternary complex of PGRP-S with lipopolysaccharide and stearic acid. | 2013 | PLoS ONE | pmid:23326499 |
| Tükel S et al. | Optimization of lipase-catalyzed synthesis of fructose stearate using response surface methodology. | 2013 | Artif Cells Nanomed Biotechnol | pmid:23305558 |
| Lee W et al. | Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress. | 2013 | J. Biol. Chem. | pmid:23306194 |
| Wu JH et al. | Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. | 2013 | Circ Cardiovasc Genet | pmid:23362303 |
| Arukuusk P et al. | New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids. | 2013 | Biochim. Biophys. Acta | pmid:23357356 |
| Khan AA et al. | Design, synthesis and in vitro anticancer evaluation of a stearic acid-based ester conjugate. | 2013 | Anticancer Res. | pmid:23749903 |
| Li C et al. | Enhanced performance and interfacial investigation of mineral-based composite phase change materials for thermal energy storage. | 2013 | Sci Rep | pmid:23712069 |
| Lakio S et al. | Challenges in detecting magnesium stearate distribution in tablets. | 2013 | AAPS PharmSciTech | pmid:23378252 |
| Järvinen MA et al. | Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release. | 2013 | Drug Dev Ind Pharm | pmid:23163644 |
| Yan J et al. | Effect of proteins with different isoelectric points on the gene transfection efficiency mediated by stearic acid grafted chitosan oligosaccharide micelles. | 2013 | Mol. Pharm. | pmid:23679858 |
| Tammaro A et al. | Magnesium stearate: an underestimated allergen. | 2012 Oct-Dec | J. Biol. Regul. Homeost. Agents | pmid:23241129 |
| Hentzschel CM et al. | Comparison of traditional and novel tableting excipients: physical and compaction properties. | 2012 Nov-Dec | Pharm Dev Technol | pmid:21740091 |
| Khan FN and Dehghan MH | Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. | 2012 Jan-Mar | Sci Pharm | pmid:22396916 |
| Pujeri SS et al. | Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. | 2012 Jan-Mar | Sci Pharm | pmid:22396908 |
| Prashanth KN and Basavaiah K | Sensitive spectrophotometric determination of atenolol in pharmaceutical formulations using bromate-bromide mixture as an eco-friendly brominating agent. | 2012 | J Anal Methods Chem | pmid:22567567 |
| de Souza Monteiro A et al. | Bioconversion of biodiesel refinery waste in the bioemulsifier by Trichosporon mycotoxinivorans CLA2. | 2012 | Biotechnol Biofuels | pmid:22559210 |
| Yang P et al. | Transcriptome analysis of the Chinese white wax scale Ericerus pela with focus on genes involved in wax biosynthesis. | 2012 | PLoS ONE | pmid:22536429 |
| Quintela M et al. | Estimation of the uncertainty associated with the results based on the validation of chromatographic analysis procedures: application to the determination of chlorides by high performance liquid chromatography and of fatty acids by high resolution gas chromatography. | 2012 | J Chromatogr A | pmid:22227361 |
| Schaab M et al. | Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action. | 2012 | PLoS ONE | pmid:22545089 |
| Gabirot M et al. | Differences in Chemical Sexual Signals May Promote Reproductive Isolation and Cryptic Speciation between Iberian Wall Lizard Populations. | 2012 | Int J Evol Biol | pmid:22288019 |
| Ghadiri M et al. | Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size. | 2012 | Int J Pharm | pmid:22227603 |
| Kim S et al. | Lipid-binding properties of TRIM72. | 2012 | BMB Rep | pmid:22281009 |
| Borbon IA et al. | Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1. | 2012 | Pharmacol. Biochem. Behav. | pmid:22202649 |
| El-Enany NM et al. | Development and validation of a repharsed phase- HPLC method for simultaneous determination of rosiglitazone and glimepiride in combined dosage forms and human plasma. | 2012 | Chem Cent J | pmid:22277722 |
| Scalia S et al. | Preparation and in vitro evaluation of salbutamol-loaded lipid microparticles for sustained release pulmonary therapy. | 2012 | J Microencapsul | pmid:22208706 |
| Anton N et al. | A new application of lipid nanoemulsions as coating agent, providing zero-order hydrophilic drug release from tablets. | 2012 | J Drug Deliv | pmid:22272376 |
| Zhen Z and Xie J | Development of manganese-based nanoparticles as contrast probes for magnetic resonance imaging. | 2012 | Theranostics | pmid:22272218 |
| Streit MR et al. | High survival in young patients using a second generation uncemented total hip replacement. | 2012 | Int Orthop | pmid:22113735 |
| Pijls BG et al. | Polyethylene thickness is a risk factor for wear necessitating insert exchange. | 2012 | Int Orthop | pmid:22105569 |
| Imarisio C et al. | Adenosine A(2a) receptor stimulation prevents hepatocyte lipotoxicity and non-alcoholic steatohepatitis (NASH) in rats. | 2012 | Clin. Sci. | pmid:22439844 |
| Rojas J and Kumar V | Effect of silicification on the tableting performance of cellulose ii: a novel multifunctional excipient. | 2012 | Chem. Pharm. Bull. | pmid:22689398 |
| Griffith EC et al. | Hydrophobic collapse of a stearic acid film by adsorbed l-phenylalanine at the air-water interface. | 2012 | J Phys Chem B | pmid:22691061 |
| Harvey KA et al. | Trans fatty acids: induction of a pro-inflammatory phenotype in endothelial cells. | 2012 | Lipids | pmid:22684911 |
| Kang JH et al. | Effects of solid carriers on the crystalline properties, dissolution and bioavailability of flurbiprofen in solid self-nanoemulsifying drug delivery system (solid SNEDDS). | 2012 | Eur J Pharm Biopharm | pmid:22119666 |
| Simmons DM and Gierer DS | A material sparing test to predict punch sticking during formulation development. | 2012 | Drug Dev Ind Pharm | pmid:22181042 |
| Niu J et al. | Octreotide-modified and pH-triggering polymeric micelles loaded with doxorubicin for tumor targeting delivery. | 2012 | Eur J Pharm Sci | pmid:22119655 |
| Masuda M et al. | Activating transcription factor 4 regulates stearate-induced vascular calcification. | 2012 | J. Lipid Res. | pmid:22628618 |
| Slobodkina GB et al. | Deferrisoma camini gen. nov., sp. nov., a moderately thermophilic, dissimilatory iron(III)-reducing bacterium from a deep-sea hydrothermal vent that forms a distinct phylogenetic branch in the Deltaproteobacteria. | 2012 | Int. J. Syst. Evol. Microbiol. | pmid:22140176 |
| Meka VS et al. | Design and in vitro evaluation of effervescent gastric floating drug delivery systems of propanolol HCl. | 2012 | Invest Clin | pmid:22524109 |
| Lalloo AK et al. | Decoupling the role of image size and calorie intake on gastric retention of swelling-based gastric retentive formulations: pre-screening in the dog model. | 2012 | Int J Pharm | pmid:22546295 |
| Chakradhar RP and Dinesh Kumar V | Water-repellent coatings prepared by modification of ZnO nanoparticles. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22575349 |
| Agostini F et al. | Supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape. | 2012 | ScientificWorldJournal | pmid:22593706 |