| MeSH term | MeSH ID | Detail |
|---|---|---|
| Boutonneuse Fever | D001907 | 5 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Syphilis, Latent | D013592 | 4 associated lipids |
| Prostatic Diseases | D011469 | 4 associated lipids |
| Legionnaires' Disease | D007877 | 4 associated lipids |
| Chancroid | D002602 | 4 associated lipids |
| Leukodystrophy, Metachromatic | D007966 | 4 associated lipids |
| Yaws | D015001 | 4 associated lipids |
| Pneumoconiosis | D011009 | 3 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Calculi | D002137 | 3 associated lipids |
| Relapsing Fever | D012061 | 3 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Obesity, Abdominal | D056128 | 3 associated lipids |
| Syphilis, Congenital | D013590 | 3 associated lipids |
| Hypothalamic Diseases | D007027 | 3 associated lipids |
| Salivary Duct Calculi | D012465 | 2 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Eczema, Dyshidrotic | D011146 | 1 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rosenthal MD and Whitehurst MC | Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. | 1983 | Biochim. Biophys. Acta | pmid:6615875 |
| Emken EA et al. | Influence of linoleic acid on desaturation and uptake of deuterium-labeled palmitic and stearic acids in humans. | 1993 | Biochim. Biophys. Acta | pmid:8399342 |
| Bieri VG and Wallach DF | Variations of lipid-protein interactions in erythrocyte ghosts as a function of temperature and pH in physiological and non-physiological ranges. A study using a paramagnetic quenching of protein fluorescence by nitroxide lipid analogues. | 1975 | Biochim. Biophys. Acta | pmid:241415 |
| Zoeller RA and Wood R | The importance of the stearoyl-CoA desaturase system in octadecenoate metabolism in the Morris hepatoma 7288C. | 1985 | Biochim. Biophys. Acta | pmid:2860925 |
| Christensen E et al. | Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. | 1989 | Biochim. Biophys. Acta | pmid:2752017 |
| Longmuir KJ and Rossi ME | Fatty acid chain-shortening activity in the pulmonary type II cell. | 1988 | Biochim. Biophys. Acta | pmid:3289622 |
| Wisniewska A et al. | Depth dependence of the perturbing effect of placing a bulky group (oxazolidine ring spin labels) in the membrane on the membrane phase transition. | 1996 | Biochim. Biophys. Acta | pmid:8611609 |
| Gorrissen H et al. | Deuterium magnetic resonance of selectively deuterated cholesteryl esters in dipalmitoyl phosphatidylcholine dispersions. | 1981 | Biochim. Biophys. Acta | pmid:6894863 |
| Kaya K and Kusumi T | Isolation and structural characterization of a diacyltaurolipid in cells of Tetrahymena mimbres. | 1988 | Biochim. Biophys. Acta | pmid:3132980 |
| Waring AJ et al. | In vivo modification of plant membrane phospholipid composition. | 1976 | Biochim. Biophys. Acta | pmid:953014 |
| Kogure K et al. | Effect of dicetylphosphate or stearic acid on spontaneous transfer of protein from influenza virus-infected cells to dimyristoylphosphatidylcholine liposomes. | 1997 | Biochim. Biophys. Acta | pmid:9370255 |
| Callaghan R et al. | Increased accumulation of drugs in a multidrug resistant cell line by alteration of membrane biophysical properties. | 1993 | Biochim. Biophys. Acta | pmid:8435444 |
| Stein Y et al. | Intralysosomal hydrolysis of cholesterol esters of varying fatty acid composition in cultured human skin fibroblasts. | 1978 | Biochim. Biophys. Acta | pmid:698242 |
| Goto M et al. | Evidence for a correlation between swimming velocity and membrane fluidity of Tetrahymena cells. | 1982 | Biochim. Biophys. Acta | pmid:6818990 |
| Bonini de Romanelli IC et al. | Phosphatidic acid, phosphatidylinositol, phosphatidylserine and cardiolipin in the course of early embryonic development. Fatty acid composition and content in whole toad embryos and in mitochondrial fractions. | 1981 | Biochim. Biophys. Acta | pmid:6791698 |
| Yamauchi T et al. | Thermal adaptation of Tetrahymena membranes with special reference to mitochondria. Role of cardiolipin in fluidity of mitochondrial membranes. | 1981 | Biochim. Biophys. Acta | pmid:6797472 |
| Murakami C et al. | A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid. | 2003 | Biochim. Biophys. Acta | pmid:12535613 |
| Whorton AR et al. | The metabolism of (1-14C) stearic acid in rat testicular tissue. | 1976 | Biochim. Biophys. Acta | pmid:1252481 |
| Chester DW et al. | The influence of saturated fatty acid modulation of bilayer physical state on cellular and membrane structure and function. | 1986 | Biochim. Biophys. Acta | pmid:3741857 |
| Schreiber R et al. | Retinyl ester hydrolases and their roles in vitamin A homeostasis. | 2012 | Biochim. Biophys. Acta | pmid:21586336 |
| Giacobino JP and Chmelar M | The role of chain elongation systems in the supplying of fatty acids to the adipocyte membrane lipids. | 1977 | Biochim. Biophys. Acta | pmid:861235 |
| Arukuusk P et al. | New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids. | 2013 | Biochim. Biophys. Acta | pmid:23357356 |
| AlegrÃa AE et al. | Semiquinones derived from anthraquinone-containing antitumor drugs can partition into phosphatidylcholine bilayers. | 1990 | Biochim. Biophys. Acta | pmid:2166575 |
| Kitagawa S et al. | Inhibitory mechanism of cis-polyunsaturated fatty acids on platelet aggregation: the relation with their effects on Ca2+ mobilization, cyclic AMP levels and membrane fluidity. | 1990 | Biochim. Biophys. Acta | pmid:2166588 |
| Anel A et al. | Fatty acid metabolism in human lymphocytes. II. Activation of fatty acid desaturase-elongase systems during blastic transformation. | 1990 | Biochim. Biophys. Acta | pmid:2114179 |
| Rich MR | Conformational analysis of arachidonic and related fatty acids using molecular dynamics simulations. | 1993 | Biochim. Biophys. Acta | pmid:8329458 |
| DAY AJ et al. | THE INCORPORATION OF 14-C-LABELLED ACETATE INTO LONG CHAIN FATTY ACIDS BY MACROPHAGES IN VITRO. | 1964 | Biochim. Biophys. Acta | pmid:14181291 |
| GELLHORN A and BENJAMIN W | THE INTRACELLULAR LOCALIZATION OF AN ENZYMATIC DEFECT OF LIPID METABOLISM IN DIABETIC RATS. | 1964 | Biochim. Biophys. Acta | pmid:14181293 |
| Katz AM et al. | Fatty acid effects on calcium influx and efflux in sarcoplasmic reticulum vesicles from rabbit skeletal muscle. | 1982 | Biochim. Biophys. Acta | pmid:7074105 |
| IKAWA M | OCCURRENCE AND IDENTIFICATION OF CIS-VACCENIC ACID IN LEUCONOSTOC MESENTEROIDES. | 1964 | Biochim. Biophys. Acta | pmid:14181302 |
| BURTON RM and GIBBONS JM | LIPID COMPOSITION OF A RAT-BRAIN SYNAPTIC-VESICLE FRACTION. | 1964 | Biochim. Biophys. Acta | pmid:14181307 |
| ROWE CE | THE OCCURRENCE AND METABOLISM IN VITRO OF UNESTERIFIED FATTY ACID IN MOUSE BRAIN. | 1964 | Biochim. Biophys. Acta | pmid:14230816 |
| KELLERMAN GM and JOLLOW DJ | CONVERSION OF STEARIC ACID INTO OLEIC ACID IN ADIPOSE TISSUE. | 1964 | Biochim. Biophys. Acta | pmid:14230826 |
| Husebye ES and Flatmark T | Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. | 1987 | Biochim. Biophys. Acta | pmid:3607074 |
| Cevc G et al. | Phosphatidylcholine-fatty acid membranes. I. Effects of protonation, salt concentration, temperature and chain-length on the colloidal and phase properties of mixed vesicles, bilayers and nonlamellar structures. | 1988 | Biochim. Biophys. Acta | pmid:2835979 |
| Masuzawa Y et al. | Distribution of dietary trans-octadecenoate among acyl-CoA and other lipid fractions of rat liver and heart. | 1987 | Biochim. Biophys. Acta | pmid:3593750 |
| Kedryna T et al. | Pyruvate kinase from cytosolic fractions of the Ehrlich ascites tumour, normal mouse liver and skeletal muscle. | 1990 | Biochim. Biophys. Acta | pmid:2354196 |
| Morimoto K and Kanoh H | The role of the de novo synthetic pathway in forming molecular species of phospholipids in resting lymphocytes from human tonsils. | 1980 | Biochim. Biophys. Acta | pmid:7353023 |
| Morandi S et al. | Association of sugar-based carboranes with cationic liposomes: an electron spin resonance and light scattering study. | 2004 | Biochim. Biophys. Acta | pmid:15238258 |
| Bazan NG et al. | High content of 22:6 (docosahexaenoate) and active [2-3H]glycerol metabolism of phosphatidic acid from photoreceptor membranes. | 1982 | Biochim. Biophys. Acta | pmid:6215065 |
| Shires SE et al. | Effects of linoleic acid and mitogenic stimulation on the fatty acid composition of human lymphocytes. | 1989 | Biochim. Biophys. Acta | pmid:2493807 |
| Höltje M et al. | Molecular dynamics simulations of stratum corneum lipid models: fatty acids and cholesterol. | 2001 | Biochim. Biophys. Acta | pmid:11248214 |
| Ellingson JS and Seenaiah B | The selective use of stearoyl-polyunsaturated molecular species of phosphatidylcholine and phosphatidylethanolamine for the synthesis of phosphatidylserine. | 1994 | Biochim. Biophys. Acta | pmid:8011673 |
| Sivarajan M et al. | Regulation of intracellular arachidonate in normal and stressed endothelial cells. | 1984 | Biochim. Biophys. Acta | pmid:6433983 |
| HEALD PJ and BADMAN HG | LIPID METABOLISM AND THE LAYING HEN. I. PLASMA-FREE FATTY ACIDS AND THE ONSET OF LAYING IN THE DOMESTIC FOWL. | 1963 | Biochim. Biophys. Acta | pmid:14067611 |
| Wirthensohn G et al. | Phospholipid metabolism in rat kidney cortical tubules. I. Effect of renal substrates. | 1984 | Biochim. Biophys. Acta | pmid:6477951 |
| Shechter Y and Henis YI | Cis-unsaturated fatty acids induce both lipogenesis and calcium binding in adipocytes. | 1984 | Biochim. Biophys. Acta | pmid:6477975 |
| Skrede S et al. | The effects of alkylthioacetic acids (3-thia fatty acids) on fatty acid metabolism in isolated hepatocytes. | 1989 | Biochim. Biophys. Acta | pmid:2804058 |
| Privat JP et al. | Incorporation of spin-labeled fatty acids into bovine brain clathrin coated vesicles. | 1990 | Biochim. Biophys. Acta | pmid:2158352 |
| ELSBACH P | COMPARISON OF UPTAKE OF PALMITIC, STEARIC, OLEIC AND LINOLEIC ACID BY POLYMORPHONUCLEAR LEUKOCYTES. | 1964 | Biochim. Biophys. Acta | pmid:14124760 |