| MeSH term | MeSH ID | Detail |
|---|---|---|
| Skin Diseases, Infectious | D012874 | 7 associated lipids |
| Spinal Cord Injuries | D013119 | 34 associated lipids |
| Syphilis, Congenital | D013590 | 3 associated lipids |
| Syphilis, Latent | D013592 | 4 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Tremor | D014202 | 15 associated lipids |
| Tuberculosis, Pulmonary | D014397 | 18 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
| Urticaria | D014581 | 13 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Whooping Cough | D014917 | 6 associated lipids |
| Yaws | D015001 | 4 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhou QT et al. | Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach. | 2011 | J Pharm Sci | pmid:21455980 |
| Sheikh KA et al. | Influence of hydration state and homologue composition of magnesium stearate on the physical chemical properties of liquid paraffin lipogels. | 2011 | Int J Pharm | pmid:21457766 |
| Severino P et al. | Polymorphism, crystallinity and hydrophilic-lipophilic balance of stearic acid and stearic acid-capric/caprylic triglyceride matrices for production of stable nanoparticles. | 2011 | Colloids Surf B Biointerfaces | pmid:21543196 |
| Zhou QT et al. | Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties. | 2011 | Int J Pharm | pmid:21527321 |
| Manzano E et al. | Study of the GC-MS determination of the palmitic-stearic acid ratio for the characterisation of drying oil in painting: La Encarnación by Alonso Cano as a case study. | 2011 | Talanta | pmid:21530791 |
| Prabhakar N et al. | Polyaniline Langmuir-Blodgett film based aptasensor for ochratoxin A detection. | 2011 | Biosens Bioelectron | pmid:21514815 |
| Fini A et al. | Diclofenac salts, part 6: release from lipid microspheres. | 2011 | J Pharm Sci | pmid:21523784 |
| Park MY et al. | Hog millet (Panicum miliaceum L.)-supplemented diet ameliorates hyperlipidemia and hepatic lipid accumulation in C57BL/6J-ob/ob mice. | 2011 | Nutr Res Pract | pmid:22259675 |
| Basu B et al. | Formulation and evaluation of fast dissolving tablets of cinnarizine using superdisintegrant blends and subliming material. | 2011 | J Adv Pharm Technol Res | pmid:22247895 |
| Guan Q et al. | Preparation and pharmacokinetics of solid lipid nanoparticles loaded with pueraria flavones. | 2011 | J Control Release | pmid:22195890 |
| Zhang Y and Clapp A | Overview of stabilizing ligands for biocompatible quantum dot nanocrystals. | 2011 | Sensors (Basel) | pmid:22247651 |
| Zhang Y et al. | α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes. | 2011 | Lipids Health Dis | pmid:21592363 |
| Ting TC et al. | Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. | 2011 | J. Biol. Chem. | pmid:21596756 |
| Pingali K et al. | Evaluation of strain-induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions. | 2011 | Drug Dev Ind Pharm | pmid:20942612 |
| Lavigne JP et al. | Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections. | 2011 | BMC Res Notes | pmid:22126300 |
| Steidl S et al. | Mâ‚… muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. | 2011 | PLoS ONE | pmid:22102904 |
| Meissner M et al. | Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate. | 2011 | PLoS ONE | pmid:22087215 |
| Guschina I et al. | Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. | 2011 | Lipids | pmid:20963507 |
| Yin AW and Huang SJ | [Research on chemical constituents of xuefu zhuyu decoction]. | 2011 | Zhong Yao Cai | pmid:22372145 |
| Bailey JA et al. | Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons. | 2011 | PLoS ONE | pmid:21799757 |
| Protière M et al. | Rational design of the gram-scale synthesis of nearly monodisperse semiconductor nanocrystals. | 2011 | Nanoscale Res Lett | pmid:21791060 |
| Rajendraprasad N et al. | Titrimetric and spectrophotometric assay of oxcarbazepine in pharmaceuticals using N-bromosuccinimide and bromopyrogallol red. | 2011 | Int J Anal Chem | pmid:21785594 |
| Bhope SG et al. | Design and development of a stable polyherbal formulation based on the results of compatibility studies. | 2011 | Pharmacognosy Res | pmid:21772756 |
| Williams KJ et al. | The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo. | 2011 | Tuberculosis (Edinb) | pmid:21764638 |
| Zhang H et al. | Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related Pathways. | 2011 | Evid Based Complement Alternat Med | pmid:21760826 |
| Lacaze C et al. | The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership. | 2011 | Malar. J. | pmid:21605361 |
| Houmard JA et al. | Is there a metabolic program in the skeletal muscle of obese individuals? | 2011 | J Obes | pmid:21603262 |
| Li C et al. | Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate. | 2011 | Carcinogenesis | pmid:21586513 |
| Mahdi ES et al. | Effect of surfactant and surfactant blends on pseudoternary phase diagram behavior of newly synthesized palm kernel oil esters. | 2011 | Drug Des Devel Ther | pmid:21792294 |
| Sahu SK et al. | Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel. | 2011 | J Drug Target | pmid:20367067 |
| Liu Y et al. | Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. | 2011 | Rapid Commun. Mass Spectrom. | pmid:22006384 |
| Santos GM et al. | Negative regulation by nuclear receptors: a plethora of mechanisms. | 2011 | Trends Endocrinol. Metab. | pmid:21196123 |
| Dasu MR and Jialal I | Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:20959532 |
| Kouskoumvekaki I and Panagiotou G | Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules. | 2011 | J. Biomed. Biotechnol. | pmid:20936122 |
| Goto T et al. | Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. | 2011 | Biochem. J. | pmid:21605082 |
| Kasliwal N et al. | Formulation, development, and performance evaluation of metoclopramide HCl oro-dispersible sustained release tablet. | 2011 | Arch. Pharm. Res. | pmid:22076769 |
| Kushner J et al. | Examining the impact of excipient material property variation on drug product quality attributes: a quality-by-design study for a roller compacted, immediate release tablet. | 2011 | J Pharm Sci | pmid:21319161 |
| de Sousa Neto D et al. | Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I). | 2011 | Chem. Phys. Lipids | pmid:21238439 |
| Seow LJ et al. | Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions. | 2011 | J Ethnopharmacol | pmid:21167271 |
| Price ER et al. | Carnitine palmitoyl transferase activity and whole muscle oxidation rates vary with fatty acid substrate in avian flight muscles. | 2011 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:21153644 |
| Liu H et al. | A surfactant-free recipe for shape-controlled synthesis of CdSe nanocrystals. | 2011 | Nanotechnology | pmid:21169661 |
| de Morais e Silva FA et al. | Rosacea fulminans in pregnancy with ocular perforation. | 2011 | J Dtsch Dermatol Ges | pmid:21366860 |
| Morinaga N et al. | Synthesis of fatty acid sterol esters using cholesterol esterase from Trichoderma sp. AS59. | 2011 | Enzyme Microb. Technol. | pmid:22113022 |
| Gao Q et al. | Synthesis and characterization of novel amphiphilic copolymer stearic acid-coupled F127 nanoparticles for nano-technology based drug delivery system. | 2011 | Colloids Surf B Biointerfaces | pmid:21906917 |
| Khan FN and Dehghan MH | Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. | 2011 | AAPS PharmSciTech | pmid:21879394 |
| Cheng YY et al. | A novel cold-adapted lipase from Sorangium cellulosum strain So0157-2: gene cloning, expression, and enzymatic characterization. | 2011 | Int J Mol Sci | pmid:22072918 |
| Du YZ et al. | Quaternary complexes composed of plasmid DNA/protamine/fish sperm DNA/stearic acid grafted chitosan oligosaccharide micelles for gene delivery. | 2011 | Int. J. Biol. Macromol. | pmid:21035503 |
| Bhattacharjee A et al. | Deposition of stearate-oleate rich seed fat in Mangifera indica is mediated by a FatA type acyl-ACP thioesterase. | 2011 | Phytochemistry | pmid:21130480 |
| Yuan H et al. | Stearic acid-g-chitosan polymeric micelle for oral drug delivery: in vitro transport and in vivo absorption. | 2011 | Mol. Pharm. | pmid:21138243 |
| Krogmann A et al. | Inflammatory response of human coronary artery endothelial cells to saturated long-chain fatty acids. | 2011 | Microvasc. Res. | pmid:21112343 |