| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Hypothalamic Diseases | D007027 | 3 associated lipids |
| Pneumoconiosis | D011009 | 3 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Legionnaires' Disease | D007877 | 4 associated lipids |
| Whooping Cough | D014917 | 6 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
| Boutonneuse Fever | D001907 | 5 associated lipids |
| Yaws | D015001 | 4 associated lipids |
| Syphilis, Congenital | D013590 | 3 associated lipids |
| Syphilis, Latent | D013592 | 4 associated lipids |
| Mycoplasmatales Infections | D009180 | 6 associated lipids |
| Eczema, Dyshidrotic | D011146 | 1 associated lipids |
| Chancroid | D002602 | 4 associated lipids |
| Relapsing Fever | D012061 | 3 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Salivary Duct Calculi | D012465 | 2 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Watanabe R et al. | Molecular cloning of a cDNA encoding a novel fatty acid-binding protein from rat skin. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8166694 |
| Lee WN et al. | Measurement of fractional lipid synthesis using deuterated water (2H2O) and mass isotopomer analysis. | 1994 | Am. J. Physiol. | pmid:8166257 |
| Darmani H et al. | Effect of interferon-gamma on membrane conformation in the macrophage-like cell line P388D. | 1993 | J. Interferon Res. | pmid:8151138 |
| Wonsil BJ et al. | Dietary and ruminally derived trans-18:1 fatty acids alter bovine milk lipids. | 1994 | J. Nutr. | pmid:8145078 |
| Golovina EA and Tikhonov AN | The structural differences between the embryos of viable and nonviable wheat seeds as studied with the EPR spectroscopy of lipid-soluble spin labels. | 1994 | Biochim. Biophys. Acta | pmid:8142440 |
| Ghaly ES et al. | Controlled release of theophylline from inert matrices: effect of channeling material on release rate. | 1993 | P R Health Sci J | pmid:8140202 |
| Rule DC | Effects of dietary fatty acid composition on glycerophosphate acyltransferase activity in rat adipose tissue and liver. | 1994 | Int. J. Biochem. | pmid:8138047 |
| Burdick S et al. | Different mechanisms of uptake of stearic acid and cholesterol into rabbit jejunal brush border membrane vesicles. | 1993 | Lipids | pmid:8121247 |
| Redgrave TG et al. | The condensing effects of egg lecithin and cholesterol on triolein monolayers are inhibited by substitution of one saturated acyl chain in the triacylglycerol. | 1994 | Biochim. Biophys. Acta | pmid:8117751 |
| Melander A | Influence of food on the bioavailability of drugs. | 1978 Sep-Oct | Clin Pharmacokinet | pmid:81118 |
| Rabinowitz JL and Myerson RM | Changes in the lipid content of rat lymph after the ingestion of [14C] long-chain fatty acids. | 1994 | Life Sci. | pmid:8107533 |
| Arnould T et al. | Increased PMN adherence on endothelial cells after hypoxia: involvement of PAF, CD18/CD11b, and ICAM-1. | 1993 | Am. J. Physiol. | pmid:8098907 |
| Sylvester PW et al. | Fatty acid modulation of epidermal growth factor-induced mouse mammary epithelial cell proliferation in vitro. | 1994 | Exp. Cell Res. | pmid:8082717 |
| Sargent JR et al. | Nervonic acid and demyelinating disease. | 1994 | Med. Hypotheses | pmid:8072429 |
| Vestemar V et al. | Binding of (+)- and (-)-isomers and racemate of etomoxir to human serum albumin and effect of stearic acid and stanozolol. | 1994 | J Pharm Sci | pmid:8046600 |
| Hoebeke M et al. | Quenching of merocyanine 540 triplet state by nitroxyl radicals in liposomal systems: a laser flash photolysis study. | 1994 | J. Photochem. Photobiol. B, Biol. | pmid:8014755 |
| Ellingson JS and Seenaiah B | The selective use of stearoyl-polyunsaturated molecular species of phosphatidylcholine and phosphatidylethanolamine for the synthesis of phosphatidylserine. | 1994 | Biochim. Biophys. Acta | pmid:8011673 |
| Taylor AJ | Erythrocyte membrane fatty acid composition in hypercholesterolaemia. | 1994 | Ann. Clin. Biochem. | pmid:7979101 |
| Kritchevsky D | Stearic acid metabolism and atherogenesis: history. | 1994 | Am. J. Clin. Nutr. | pmid:7977159 |
| Grundy SM | Influence of stearic acid on cholesterol metabolism relative to other long-chain fatty acids. | 1994 | Am. J. Clin. Nutr. | pmid:7977157 |