stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Cholestasis, Extrahepatic D001651 7 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Infertility D007246 3 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Chancroid D002602 4 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
de Souza Monteiro A et al. Bioconversion of biodiesel refinery waste in the bioemulsifier by Trichosporon mycotoxinivorans CLA2. 2012 Biotechnol Biofuels pmid:22559210
Zanon NC et al. Immbolization of uricase enzyme in Langmuir and Langmuir-Blodgett films of fatty acids: possible use as a uric acid sensor. 2012 J Colloid Interface Sci pmid:21875709
Kim S et al. Lipid-binding properties of TRIM72. 2012 BMB Rep pmid:22281009
Hao J et al. Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design. 2012 Eur J Pharm Sci pmid:22820033
Simmons DM and Gierer DS A material sparing test to predict punch sticking during formulation development. 2012 Drug Dev Ind Pharm pmid:22181042
Xie J et al. Composition of fatty oils from semen ziziphi spinosae and its cardiotonic effect on isolated toad hearts. 2012 Nat. Prod. Res. pmid:21707231
Brown PN et al. Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension. 2011 Sep-Oct J AOAC Int pmid:22165004
Tomuta I et al. High-Throughput NIR-Chemometric Method for Meloxicam Assay from Powder Blends for Tableting. 2011 Oct-Dec Sci Pharm pmid:22145112
Nanjwade BK et al. Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. 2011 Oct-Dec Sci Pharm pmid:22145101
Jelvehgari M et al. Formulation, characterization and in vitro evaluation of theophylline-loaded Eudragit RS 100 microspheres prepared by an emulsion-solvent diffusion/evaporation technique. 2011 Nov-Dec Pharm Dev Technol pmid:20722498
Qu WX et al. Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. 2011 May-Jun Phytochem Anal pmid:20848395
Nath B et al. Preparation and in vitro dissolution profile of zidovudine loaded microspheres made of Eudragit RS 100, RL 100 and their combinations. 2011 May-Jun Acta Pol Pharm pmid:21648196
BozdaÄŸ-Pehlivan S et al. Evaluation of drug-excipient interaction in the formulation of celecoxib tablets. 2011 May-Jun Acta Pol Pharm pmid:21648198
Malik K et al. Taste masked microspheres of ofloxacin: formulation and evaluation of orodispersible tablets. 2011 Jul-Sep Sci Pharm pmid:21886910
Zaid AN et al. Formulation and bioequivalence of two valsartan tablets after a single oral administration. 2011 Jan-Mar Sci Pharm pmid:21617777
Shah DA et al. Stability indicating LC-method for estimation of paracetamol and lornoxicam in combined dosage form. 2011 Jan-Mar Sci Pharm pmid:21617776
Uchino T et al. Effects of coating materials and size of titanium dioxide particles on their cytotoxicity and penetration into the cellular membrane. 2011 J Toxicol Sci pmid:21297346
Shin S et al. Time-oriented experimental design method to optimize hydrophilic matrix formulations with gelation kinetics and drug release profiles. 2011 Int J Pharm pmid:21251963
Calegari VC et al. Inflammation of the hypothalamus leads to defective pancreatic islet function. 2011 J. Biol. Chem. pmid:21257748
Uchimoto T et al. A comparative study of glycerin fatty acid ester and magnesium stearate on the dissolution of acetaminophen tablets using the analysis of available surface area. 2011 Eur J Pharm Biopharm pmid:21284955
Subczynski WK et al. Spin-label oximetry at Q- and W-band. 2011 J. Magn. Reson. pmid:21277814
Park MY et al. Hog millet (Panicum miliaceum L.)-supplemented diet ameliorates hyperlipidemia and hepatic lipid accumulation in C57BL/6J-ob/ob mice. 2011 Nutr Res Pract pmid:22259675
Steidl S et al. Mâ‚… muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. 2011 PLoS ONE pmid:22102904
Meissner M et al. Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate. 2011 PLoS ONE pmid:22087215
Guschina I et al. Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. 2011 Lipids pmid:20963507
Protière M et al. Rational design of the gram-scale synthesis of nearly monodisperse semiconductor nanocrystals. 2011 Nanoscale Res Lett pmid:21791060
Rajendraprasad N et al. Titrimetric and spectrophotometric assay of oxcarbazepine in pharmaceuticals using N-bromosuccinimide and bromopyrogallol red. 2011 Int J Anal Chem pmid:21785594
Bhope SG et al. Design and development of a stable polyherbal formulation based on the results of compatibility studies. 2011 Pharmacognosy Res pmid:21772756
Williams KJ et al. The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo. 2011 Tuberculosis (Edinb) pmid:21764638
Lacaze C et al. The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership. 2011 Malar. J. pmid:21605361
Houmard JA et al. Is there a metabolic program in the skeletal muscle of obese individuals? 2011 J Obes pmid:21603262
Li C et al. Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate. 2011 Carcinogenesis pmid:21586513
Mahdi ES et al. Effect of surfactant and surfactant blends on pseudoternary phase diagram behavior of newly synthesized palm kernel oil esters. 2011 Drug Des Devel Ther pmid:21792294
Dasu MR and Jialal I Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959532
Goto T et al. Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. 2011 Biochem. J. pmid:21605082
Kushner J et al. Examining the impact of excipient material property variation on drug product quality attributes: a quality-by-design study for a roller compacted, immediate release tablet. 2011 J Pharm Sci pmid:21319161
de Sousa Neto D et al. Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I). 2011 Chem. Phys. Lipids pmid:21238439
Seow LJ et al. Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions. 2011 J Ethnopharmacol pmid:21167271
Price ER et al. Carnitine palmitoyl transferase activity and whole muscle oxidation rates vary with fatty acid substrate in avian flight muscles. 2011 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:21153644
Liu H et al. A surfactant-free recipe for shape-controlled synthesis of CdSe nanocrystals. 2011 Nanotechnology pmid:21169661
Pingali K et al. Mixing order of glidant and lubricant--influence on powder and tablet properties. 2011 Int J Pharm pmid:21356286
Zaki Rizkalla CM et al. In vitro and in vivo evaluation of hydroxyzine hydrochloride microsponges for topical delivery. 2011 AAPS PharmSciTech pmid:21800216
Roblegg E et al. Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion. 2011 Eur J Pharm Biopharm pmid:21801834
Van Hoeck V et al. Elevated non-esterified fatty acid concentrations during bovine oocyte maturation compromise early embryo physiology. 2011 PLoS ONE pmid:21858021
Morinaga N et al. Synthesis of fatty acid sterol esters using cholesterol esterase from Trichoderma sp. AS59. 2011 Enzyme Microb. Technol. pmid:22113022
Someshwar K et al. Formulation and evaluation of effervescent floating tablets of tizanidine hydrochloride. 2011 Acta Pharm pmid:21684848
Pani NR et al. Compatibility studies of nateglinide with excipients in immediate release tablets. 2011 Acta Pharm pmid:21684850
Němcová-Fürstová V et al. Inhibitory effect of unsaturated fatty acids on saturated fatty acid-induced apoptosis in human pancreatic β-cells: activation of caspases and ER stress induction. 2011 Cell. Physiol. Biochem. pmid:21691070
Xu M et al. Novel functions of lipid-binding protein 5 in Caenorhabditis elegans fat metabolism. 2011 J. Biol. Chem. pmid:21697096
White HM et al. Differential regulation of bovine pyruvate carboxylase promoters by fatty acids and peroxisome proliferator-activated receptor-α agonist. 2011 J. Dairy Sci. pmid:21700028