stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Cholestasis, Extrahepatic D001651 7 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Infertility D007246 3 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Chancroid D002602 4 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
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Catalá A Stearic acid desaturation in rat liver microsomes: stimulation by fatty acid binding protein. 1986 Acta Physiol Pharmacol Latinoam pmid:2876583
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Singh H and Poulos A A comparative study of stearic and lignoceric acid oxidation by human skin fibroblasts. 1986 Arch. Biochem. Biophys. pmid:3767370
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Boiron F et al. A comparison of substrate-dependent fatty acyl-CoA synthetase activities and ATP hydrolysis in membrane pellets from normal and trembler mouse sciatic nerves. 1985 Neurochem. Int. pmid:20492990
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Kaplan E and Ansari K High-performance liquid chromatography as a tool for identification of linolenic acid hydroperoxide prepared with soybean lipoxygenase. 1985 J. Chromatogr. pmid:3937844
Maiti H and Haye KR Does detection of chlamydial antibodies by microimmunofluorescence help in managing chlamydial lower genital tract infection in women? 1985 Genitourin Med pmid:3891584
Walker KA and Harwood JL Localization of chloroplastic fatty acid synthesis de novo in the stroma. 1985 Biochem. J. pmid:3994672
Jones PJ et al. Absorption of 13C-labeled stearic, oleic, and linoleic acids in humans: application to breath tests. 1985 J. Lab. Clin. Med. pmid:3998617
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Wadström T et al. Hydrophobized wound dressing in the treatment of experimental Staphylococcus aureus infections in the young pig. 1985 Acta Pathol Microbiol Immunol Scand B pmid:2417448
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Harrison GA et al. Resistance in oral streptococci after repeated three-dose erythromycin prophylaxis. 1985 J. Antimicrob. Chemother. pmid:4008379
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Fujii M et al. Fatty acid compositions of triacylglycerols and phospholipids in hen liver lipid before and after sexual maturity. 1985 Poult. Sci. pmid:4022907
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Ruwart MJ et al. 16,16-Dimethyl PGE2 and fatty acids protect hepatocytes against CCl4-induced damage. 1985 In Vitro Cell. Dev. Biol. pmid:4030626
Sklan D et al. Digestion and absorption of lipids and bile acids in sheep fed stearic acid, oleic acid, or tristearin. 1985 J. Dairy Sci. pmid:4031186