| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Seizures | D012640 | 87 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Matsuura T et al. | Effect of Alcohols on the Phase Behavior and Emulsification of a Sucrose Fatty Acid Ester/Water/Edible Oil System. | 2018 | J Oleo Sci | pmid:29367483 |
| Beg S et al. | QbD-driven development and evaluation of nanostructured lipid carriers (NLCs) of Olmesartan medoxomil employing multivariate statistical techniques. | 2018 | Drug Dev Ind Pharm | pmid:29048242 |
| Kondo H et al. | Effect of the External Lubrication Method for a Rotary Tablet Press on the Adhesion of the Film Coating Layer. | 2017 | Chem. Pharm. Bull. | pmid:28867712 |
| Shiino K et al. | Melt Adsorption as a Manufacturing Method for Fine Particles of Wax Matrices without Any Agglomerates. | 2017 | Chem. Pharm. Bull. | pmid:28768926 |
| Guan Q et al. | In vitro and in vivo evaluation of docetaxel-loaded stearic acid-modified Bletilla striata polysaccharide copolymer micelles. | 2017 | PLoS ONE | pmid:28334044 |
| Shazly GA | Ciprofloxacin Controlled-Solid Lipid Nanoparticles: Characterization, In Vitro Release, and Antibacterial Activity Assessment. | 2017 | Biomed Res Int | pmid:28194408 |
| Mirabi P et al. | The role of fatty acids on ICSI outcomes: a prospective cohort study. | 2017 | Lipids Health Dis | pmid:28109274 |
| Dohi M et al. | Application of Terahertz Attenuated Total Reflection Spectroscopy to Detect Changes in the Physical Properties of Lactose during the Lubrication Process Required for Drug Formulation. | 2017 | Chem. Pharm. Bull. | pmid:27928130 |
| Liu Q et al. | Genetic enhancement of palmitic acid accumulation in cotton seed oil through RNAi down-regulation of ghKAS2 encoding β-ketoacyl-ACP synthase II (KASII). | 2017 | Plant Biotechnol. J. | pmid:27381745 |
| Houghton SC et al. | Intake of dietary fat and fat subtypes and risk of premenstrual syndrome in the Nurses' Health Study II. | 2017 | Br. J. Nutr. | pmid:29189192 |
| Yamamoto K et al. | Effect of Magnesium Stearate Mono- and Dihydrate Dispersibilities on Physical Properties of Tablets. | 2017 | Chem. Pharm. Bull. | pmid:29093289 |
| Soliman HM et al. | Synthesis and Application of a New Amphiphilic Antioxidant. | 2017 | J Oleo Sci | pmid:29021490 |
| Meng Y et al. | Stearic acid suppresses mammary gland development by inhibiting PI3K/Akt signaling pathway through GPR120 in pubertal mice. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28712865 |
| Prasinou P et al. | Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells. | 2017 | Biochim Biophys Acta Biomembr | pmid:28688796 |
| Oki E et al. | Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil. | 2017 | Br. J. Nutr. | pmid:28633686 |
| Naing C and Whittaker MA | Anabolic steroids for treating pressure ulcers. | 2017 | Cochrane Database Syst Rev | pmid:28631809 |
| Wan Y et al. | Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery. | 2017 | Nanomedicine (Lond) | pmid:28093948 |
| Cella C et al. | Calcium Stearate as an Effective Alternative to Poly(vinyl alcohol) in Poly-Lactic-co-Glycolic Acid Nanoparticles Synthesis. | 2017 | Biomacromolecules | pmid:28030952 |
| Zhao L et al. | Serum stearic acid/palmitic acid ratio as a potential predictor of diabetes remission after Roux-en-Y gastric bypass in obesity. | 2017 | FASEB J. | pmid:28007782 |
| Hsein H et al. | Denatured Whey Protein Powder as a New Matrix Excipient: Design and Evaluation of Mucoadhesive Tablets for Sustained Drug Release Applications. | 2017 | Pharm. Res. | pmid:28004316 |
| Bayard M et al. | Free fatty acids and their esters modulate isothermal crystallization of anhydrous milk fat. | 2017 | Food Chem | pmid:27719901 |
| Thirupathi G et al. | Role of Isradipine Loaded Solid Lipid Nanoparticles on the Pharmacodynamic Effect in Rats. | 2017 | Drug Res (Stuttg) | pmid:27992936 |
| Wahl PR et al. | Continuous monitoring of API content, API distribution and crushing strength after tableting via near-infrared chemical imaging. | 2017 | Int J Pharm | pmid:27923700 |
| Oyeyinka SA et al. | Physicochemical and Mechanical Properties of Bambara Groundnut Starch Films Modified with Stearic Acid. | 2017 | J. Food Sci. | pmid:27886659 |
| De Weirdt R et al. | Mucosa-associated biohydrogenating microbes protect the simulated colon microbiome from stress associated with high concentrations of poly-unsaturated fat. | 2017 | Environ. Microbiol. | pmid:27883264 |
| Heim CB and Gillman JD | Genotyping-by-Sequencing-Based Investigation of the Genetic Architecture Responsible for a ∼Sevenfold Increase in Soybean Seed Stearic Acid. | 2017 | G3 (Bethesda) | pmid:27866151 |
| Anbalagan P et al. | Influence of the Punch Head Design on the Physical Quality of Tablets Produced in a Rotary Press. | 2017 | J Pharm Sci | pmid:27842972 |
| Delaney SP et al. | Characterization of Synthesized and Commercial Forms of Magnesium Stearate Using Differential Scanning Calorimetry, Thermogravimetric Analysis, Powder X-Ray Diffraction, and Solid-State NMR Spectroscopy. | 2017 | J Pharm Sci | pmid:27836109 |
| Dudhipala N and Veerabrahma K | Improved anti-hyperlipidemic activity of Rosuvastatin Calcium via lipid nanoparticles: Pharmacokinetic and pharmacodynamic evaluation. | 2017 | Eur J Pharm Biopharm | pmid:27810472 |
| Song S et al. | Identification of pork flavour precursors from enzyme-treated lard using Maillard model system assessed by GC-MS and partial least squares regression. | 2017 | Meat Sci. | pmid:27792915 |
| Han Y et al. | Natural variations in stearoyl-acp desaturase genes affect the conversion of stearic to oleic acid in maize kernel. | 2017 | Theor. Appl. Genet. | pmid:27717956 |
| Narang AS et al. | Assessment of Tablet Surface Hardness by Laser Ablation and Its Correlation With the Erosion Tendency of Core Tablets. | 2017 | J Pharm Sci | pmid:27686683 |
| Liu W and Lu G | Partial Hydrogenation of Sunflower Oil-derived FAMEs Catalyzed by the Efficient and Recyclable Palladium Nanoparticles in Polyethylene Glycol. | 2017 | J Oleo Sci | pmid:28924078 |
| Ivanova EP et al. | Bactericidal activity of self-assembled palmitic and stearic fatty acid crystals on highly ordered pyrolytic graphite. | 2017 | Acta Biomater | pmid:28688988 |
| Spigoni V et al. | Stearic acid at physiologic concentrations induces in vitro lipotoxicity in circulating angiogenic cells. | 2017 | Atherosclerosis | pmid:28892713 |
| Xue J et al. | A novel and organic solvent-free preparation of solid lipid nanoparticles using natural biopolymers as emulsifier and stabilizer. | 2017 | Int J Pharm | pmid:28802794 |
| Lapham DP and Lapham JL | Gas adsorption on commercial magnesium stearate: Effects of degassing conditions on nitrogen BET surface area and isotherm characteristics. | 2017 | Int J Pharm | pmid:28779986 |
| Nagy B et al. | In-line Raman spectroscopic monitoring and feedback control of a continuous twin-screw pharmaceutical powder blending and tableting process. | 2017 | Int J Pharm | pmid:28723408 |
| Soni K et al. | Lipid drug conjugate nanoparticle as a potential nanocarrier for the oral delivery of pemetrexed diacid: Formulation design, characterization, ex vivo, and in vivo assessment. | 2017 | Int. J. Biol. Macromol. | pmid:28499946 |
| Chang C et al. | pH-responsive nanoparticle assembly from peptide amphiphiles for tumor targeting drug delivery. | 2017 | J Biomater Sci Polym Ed | pmid:28467173 |
| Shilpi D et al. | Improved Stability and Enhanced Oral Bioavailability of Atorvastatin Loaded Stearic Acid Modified Gelatin Nanoparticles. | 2017 | Pharm. Res. | pmid:28466393 |
| Lakhssassi N et al. | Stearoyl-Acyl Carrier Protein Desaturase Mutations Uncover an Impact of Stearic Acid in Leaf and Nodule Structure. | 2017 | Plant Physiol. | pmid:28461402 |
| Noor NM et al. | Preparation and characterization of dutasteride-loaded nanostructured lipid carriers coated with stearic acid-chitosan oligomer for topical delivery. | 2017 | Eur J Pharm Biopharm | pmid:28412472 |
| Sapra M et al. | Engineering of layered, lipid-encapsulated drug nanoparticles through spray-drying. | 2017 | Colloids Surf B Biointerfaces | pmid:28340484 |
| Lee W et al. | Novel protein acetyltransferase, Rv2170, modulates carbon and energy metabolism in Mycobacterium tuberculosis. | 2017 | Sci Rep | pmid:28250431 |
| Crowley ME et al. | Near-infrared monitoring of roller compacted ribbon density: Investigating sources of variation contributing to noisy spectral data. | 2017 | Eur J Pharm Sci | pmid:28216342 |
| Lau M et al. | Investigation into the Manufacture and Properties of Inhalable High-Dose Dry Powders Produced by Comilling API and Lactose with Magnesium Stearate. | 2017 | AAPS PharmSciTech | pmid:28070849 |
| Thotakura N et al. | Chitosan-Stearic Acid Based Polymeric Micelles for the Effective Delivery of Tamoxifen: Cytotoxic and Pharmacokinetic Evaluation. | 2017 | AAPS PharmSciTech | pmid:27287243 |
| Zhou Y et al. | An oxygen slow-releasing material and its application in water remediation as oxygen supplier. | 2017 | Environ Technol | pmid:28041538 |
| Kelidari HR et al. | Development and Optimisation of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability. | 2017 | AAPS PharmSciTech | pmid:27834054 |