stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Zhang JW et al. [Studies on the chemical constituents of Toricellia angulata var. intermedia]. 2010 Zhong Yao Cai pmid:21434432
Salem HF Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats. 2010 Int J Nanomedicine pmid:21187946
Daraghmeh N et al. Preparation and characterization of a novel co-processed excipient of chitin and crystalline mannitol. 2010 AAPS PharmSciTech pmid:21052880
Legrand P and Rioux V The complex and important cellular and metabolic functions of saturated fatty acids. 2010 Lipids pmid:20625935
Hodson L et al. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20628024
Seerapu S and Srinivasan BP Development and Validation of RP-HPLC Method for the Estimation of Ivabradine Hydrochloride in Tablets. 2010 Indian J Pharm Sci pmid:21695008
Kharia AA et al. Design and optimization of floating drug delivery system of acyclovir. 2010 Indian J Pharm Sci pmid:21694992
Liu TY and Lin YL Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs. 2010 Acta Biomater pmid:19819354
Jeevanandham S et al. Sustain-release of various drugs from leucaena leucocephala polysaccharide. 2010 J Young Pharm pmid:21331185
Kiss H et al. Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). 2010 Stand Genomic Sci pmid:21304711
Uchimoto T et al. Lubrication properties of potential alternative lubricants, glycerin fatty acid esters, to magnesium stearate. 2010 Int J Pharm pmid:19913080
Muro M et al. A conformation and orientation model of the carboxylic group of fatty acids dependent on chain length in a Langmuir monolayer film studied by polarization-modulation infrared reflection absorption spectroscopy. 2010 J Phys Chem B pmid:20718412
Nouri A et al. Effect of process control agent on the porous structure and mechanical properties of a biomedical Ti-Sn-Nb alloy produced by powder metallurgy. 2010 Acta Biomater pmid:19815096
Liu RS and Tang YJ Quantitative analysis for the effect of plant oil and fatty acid on Tuber melanosporum culture by uniform design combined with partial least squares regression. 2010 Appl. Microbiol. Biotechnol. pmid:20473608
Sun H et al. Complete genome sequence of Desulfarculus baarsii type strain (2st14). 2010 Stand Genomic Sci pmid:21304732
Pennick G et al. Superior effect of isostearyl isostearate on improvement in stratum corneum water permeability barrier function as examined by the plastic occlusion stress test. 2010 Int J Cosmet Sci pmid:20642769
Song HJ et al. Effect of probiotic Lactobacillus (Lacidofil® cap) for the prevention of antibiotic-associated diarrhea: a prospective, randomized, double-blind, multicenter study. 2010 J. Korean Med. Sci. pmid:21165295
Chen JL et al. Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry. 2010 World J. Gastroenterol. pmid:21155010
Kajiro H et al. Flexible two-dimensional square-grid coordination polymers: structures and functions. 2010 Int J Mol Sci pmid:21152303
Coulon C et al. Chemical analysis of cellular and extracellular carbohydrates of a biofilm-forming strain Pseudomonas aeruginosa PA14. 2010 PLoS ONE pmid:21151973
Wieder DR and Pattimakiel L Examining the efficacy, safety, and patient acceptability of the combined contraceptive vaginal ring (NuvaRing). 2010 Int J Womens Health pmid:21151688
Kanjanavas P et al. Purification and characterization of organic solvent and detergent tolerant lipase from thermotolerant Bacillus sp. RN2. 2010 Int J Mol Sci pmid:21152301
Huang WH et al. Development of liposomal salbutamol sulfate dry powder inhaler formulation. 2010 Biol. Pharm. Bull. pmid:20190418
Jeong SH and Park K Simple preparation of coated resin complexes and their incorporation into fast-disintegrating tablets. 2010 Arch. Pharm. Res. pmid:20191352
Cho KH et al. Monoacylglycerol (MAG)-oleic acid has stronger antioxidant, anti-atherosclerotic, and protein glycation inhibitory activities than MAG-palmitic acid. 2010 J Med Food pmid:20136442
Yang X et al. In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. 2010 Drug Dev Ind Pharm pmid:20141448
Du YZ et al. Stearic acid grafted chitosan oligosaccharide micelle as a promising vector for gene delivery system: factors affecting the complexation. 2010 Int J Pharm pmid:20170716
Baki G et al. Role of surface free energy and spreading coefficient in the formulation of active agent-layered pellets. 2010 Eur J Pharm Biopharm pmid:19931611
Bolton B and Halpern BP Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. 2010 Chem. Senses pmid:20100787
Wang Q et al. One-Step Synthesis of Monodisperse In-Doped ZnO Nanocrystals. 2010 Nanoscale Res Lett pmid:20672040
Lu L et al. Near infrared spectroscopy of stearic acid adsorbed on montmorillonite. 2010 Spectrochim Acta A Mol Biomol Spectrosc pmid:20071218
Pöllänen E et al. Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle. 2010 Age (Dordr) pmid:20640546
Gentile CL et al. Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin. 2010 Mol. Cell. Biochem. pmid:20607591
Bele MH et al. Effect of Flow Aids on Mucoadhesive Properties of Polymeric Discs of Polyoxyethylene and Carbopol 971P. 2010 Indian J Pharm Sci pmid:20582205
Rao KS and Srinivas K RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form. 2010 Indian J Pharm Sci pmid:20582199
Keny RV et al. Formulation and evaluation of rizatriptan benzoate mouth disintegrating tablets. 2010 Indian J Pharm Sci pmid:20582194
Li LO et al. Early hepatic insulin resistance in mice: a metabolomics analysis. 2010 Mol. Endocrinol. pmid:20150186
Moore F et al. Improving the hardness of dry granulated tablets containing sodium lauryl sulfate. 2010 Int J Pharm pmid:20801204
Chen X et al. Plasma metabolomics reveals biomarkers of the atherosclerosis. 2010 J Sep Sci pmid:20730840
Horne I et al. Two conserved Z9-octadecanoic acid desaturases in the red flour beetle, Tribolium castaneum. 2010 Gene pmid:20709164
Ion G et al. Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring. 2010 BMC Cancer pmid:20205934
Vlachou M et al. Utilization of hydrophilic swellable polymers as carriers for sustained drug delivery from matrices and three layer tablet systems. 2010 Curr Drug Deliv pmid:20695845
Mas S et al. Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes. 2010 Diabetes pmid:20200316
Walker S et al. Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery. 2010 Mol. Pharm. pmid:20669974
Kurian GA et al. Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. 2010 Chin Med pmid:20180993
Saravanakumari P and Mani K Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. 2010 Bioresour. Technol. pmid:20637606
Mathew M et al. Elevated plasma free fatty acids increase cardiovascular risk by inducing plasma biomarkers of endothelial activation, myeloperoxidase and PAI-1 in healthy subjects. 2010 Cardiovasc Diabetol pmid:20158910
Dong J et al. Cation-controlled crystal growth of silver stearate: cryo-TEM investigation of lithium vs sodium stearate. 2010 Langmuir pmid:20017506
Fu X et al. A rapid and universal bacteria-counting approach using CdSe/ZnS/SiO2 composite nanoparticles as fluorescence probe. 2010 Anal Bioanal Chem pmid:20016878
Kushner J and Moore F Scale-up model describing the impact of lubrication on tablet tensile strength. 2010 Int J Pharm pmid:20667504
Zhang LJ et al. Hot-injection synthesis of highly luminescent and monodisperse CdS nanocrystals using thioacetamide and cadmium source with proper reactivity. 2010 J Colloid Interface Sci pmid:19932894
Imae R et al. Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. 2010 Mol. Biol. Cell pmid:20668164
Su C et al. A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC. 2010 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:20732836
Yoo HJ and HÃ¥kansson K Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. 2010 Anal. Chem. pmid:20704384
Balani PN et al. Influence of excipients in comilling on mitigating milling-induced amorphization or structural disorder of crystalline pharmaceutical actives. 2010 J Pharm Sci pmid:19902526
Yuan Y et al. A signal-on electrochemical probe-label-free aptasensor using gold-platinum alloy and stearic acid as enhancers. 2010 Biosens Bioelectron pmid:20708400
Jian WX et al. [Detection and analysis on plasma metabolomics in patient with coronary heart disease of Xin-blood stasis syndrome pattern]. 2010 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:20815270
Gonzalez-Mira E et al. Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC. 2010 Colloids Surf B Biointerfaces pmid:20719479
Valencia-Chamorro SA et al. Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins. 2010 J. Food Sci. pmid:21535515
Alloatti A et al. Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. 2010 PLoS ONE pmid:21151902
Alshamsan A et al. Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine. 2009 Jan-Feb Mol. Pharm. pmid:19053537
Sahoo RR and Biswas SK Frictional response of fatty acids on steel. 2009 J Colloid Interface Sci pmid:19232636
Hu FQ et al. Enhanced cellular uptake of chlorine e6 mediated by stearic acid-grafted chitosan oligosaccharide micelles. 2009 J Drug Target pmid:19343607
Pouget EM et al. The initial stages of template-controlled CaCO3 formation revealed by cryo-TEM. 2009 Science pmid:19286549
Yadav VR et al. Novel formulation of solid lipid microparticles of curcumin for anti-angiogenic and anti-inflammatory activity for optimization of therapy of inflammatory bowel disease. 2009 J. Pharm. Pharmacol. pmid:19222903
Okuda Y et al. A new formulation for orally disintegrating tablets using a suspension spray-coating method. 2009 Int J Pharm pmid:19686825
Nonomura Y et al. Phase behavior of bile acid/lipid/water systems containing model dietary lipids. 2009 J Colloid Interface Sci pmid:19682701
Huang J et al. Quality by design case study: an integrated multivariate approach to drug product and process development. 2009 Int J Pharm pmid:19664698
Cao C et al. [Chemical study on petroleum ether portion of Sarcandra hainanensis]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19639789
Gupta A et al. Difference in the lubrication efficiency of bovine and vegetable-derived magnesium stearate during tabletting. 2009 AAPS PharmSciTech pmid:19390976
Sakuradani E et al. Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4. 2009 Appl. Microbiol. Biotechnol. pmid:19415268
Staiger H et al. Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans. 2009 Diabetes pmid:19074989
Bao Y et al. Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers. 2009 J. Proteome Res. pmid:19714868
Wang YY et al. [Studies on the chemical constituents of Sarcopyramis nepalensis]. 2009 Zhong Yao Cai pmid:20034215
Madgulkar AR et al. Formulation and optimization of sustained release tablets of venlafaxine resinates using response surface methodology. 2009 Indian J Pharm Sci pmid:20502544
Mukherjee S et al. Solid lipid nanoparticles: a modern formulation approach in drug delivery system. 2009 Indian J Pharm Sci pmid:20502539
Arayne MS et al. Spectrophotometric Quantitation of Metformin in Bulk Drug and Pharmaceutical Formulations using Multivariate Technique. 2009 Indian J Pharm Sci pmid:20490308
Leonardi R et al. Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. 2009 J. Biol. Chem. pmid:19666474
Darwish IA et al. New spectrophotometric and fluorimetric methods for determination of fluoxetine in pharmaceutical formulations. 2009 Int J Anal Chem pmid:20107560
Darwish IA et al. Simple spectrophotometric method for determination of paroxetine in tablets using 1,2-naphthoquinone-4-sulphonate as a chromogenic reagent. 2009 Int J Anal Chem pmid:20107559
Guo L and Qing Li G Olfactory perception of oviposition-deterring fatty acids and their methyl esters by the Asian corn borer, Ostrinia furnacalis. 2009 J. Insect Sci. pmid:20053122
Lee HB et al. Production of calcium-stearate by lipase using hydrogenated beef tallow. 2009 Appl. Biochem. Biotechnol. pmid:18506631
Ye YQ et al. Enhanced cytotoxicity of core modified chitosan based polymeric micelles for doxorubicin delivery. 2009 J Pharm Sci pmid:18563810
Amorim EA et al. Effect of cholesterol or cholesteryl conjugates on the cryosurvival of bull sperm. 2009 Cryobiology pmid:19159623
Rittermeier A et al. The formation of colloidal copper nanoparticles stabilized by zinc stearate: one-pot single-step synthesis and characterization of the core-shell particles. 2009 Phys Chem Chem Phys pmid:19756292
Jiang L et al. Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway. 2009 PLoS ONE pmid:19727392
Lakshmi RV and Basu BJ Fabrication of superhydrophobic sol-gel composite films using hydrophobically modified colloidal zinc hydroxide. 2009 J Colloid Interface Sci pmid:19720382
Alagna F et al. Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development. 2009 BMC Genomics pmid:19709400
Lozano MM and Longo ML Microbubbles coated with disaturated lipids and DSPE-PEG2000: phase behavior, collapse transitions, and permeability. 2009 Langmuir pmid:19708150
Spaniol B et al. Compressional behavior of a mixture of granules containing high load of Phyllanthus niruri spray-dried extract and granules of adjuvants: comparison between eccentric and rotary tablet machines. 2009 AAPS PharmSciTech pmid:19662537
Mukherjee S et al. Chemistry at air/water interface versus reaction in a flask: tuning molecular conformation in thin films. 2009 Langmuir pmid:19708145
Singh R et al. Mapping quantitative trait loci (QTLs) for fatty acid composition in an interspecific cross of oil palm. 2009 BMC Plant Biol. pmid:19706196
Anderson BM and Ma DW Are all n-3 polyunsaturated fatty acids created equal? 2009 Lipids Health Dis pmid:19664246
Chin PT et al. Highly luminescent ultranarrow Mn doped ZnSe nanowires. 2009 Nano Lett. pmid:19146460
Begat P et al. The role of force control agents in high-dose dry powder inhaler formulations. 2009 J Pharm Sci pmid:19067395
Kaye RS et al. Development and testing of particulate formulations for the nasal delivery of antibodies. 2009 J Control Release pmid:19059291
Ren X et al. Nonionic surfactants are strong inhibitors of cytochrome P450 3A biotransformation activity in vitro and in vivo. 2009 Eur J Pharm Sci pmid:19041719
García MS et al. Development of membrane selective electrode for determination of the antipsychotic sulpiride in pharmaceuticals and urine. 2009 Sensors (Basel) pmid:22408528
Rico S et al. Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines. 2009 J Asthma Allergy pmid:21437146
Chen CJ et al. Preparation of Monodisperse Iron Oxide Nanoparticles via the Synthesis and Decomposition of Iron Fatty Acid Complexes. 2009 Nanoscale Res Lett pmid:20628451