stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Nishioka Y and Yoshino H Lymphatic targeting with nanoparticulate system. 2001 Adv. Drug Deliv. Rev. pmid:11251245
Hatta I et al. X-ray diffraction study on ordered, disordered and reconstituted intercellular lipid lamellar structure in stratum corneum. 2001 Biophys. Chem. pmid:11254216
Alves MM et al. Effects of lipids and oleic acid on biomass development in anaerobic fixed-bed reactors. Part II: Oleic acid toxicity and biodegradability. 2001 Water Res. pmid:11257881
Harwood JL and James AT Metabolism of trans-3-hexadecenoic acid in broad bean. 1975 Eur. J. Biochem. pmid:1126340
Fukui E et al. Effect of magnesium stearate or calcium stearate as additives on dissolution profiles of diltiazem hydrochloride from press-coated tablets with hydroxypropylmethylcellulose acetate succinate in the outer shell. 2001 Int J Pharm pmid:11274815
Liu Q et al. Genetic modification of cotton seed oil using inverted-repeat gene-silencing techniques. 2000 Biochem. Soc. Trans. pmid:11288706
van den Bergh BA et al. Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements. 2001 Int J Pharm pmid:11292538
Kelly FD et al. A stearic acid-rich diet improves thrombogenic and atherogenic risk factor profiles in healthy males. 2001 Eur J Clin Nutr pmid:11305631
Oviedo JM et al. Pulmonary surfactant protein SP-B is significantly more immunoreactive in anionic than in zwitterionic bilayers. 2001 FEBS Lett. pmid:11311247
Pacia SV et al. Biogenic amines in the human neocortex in patients with neocortical and mesial temporal lobe epilepsy: identification with in situ microvoltammetry. 2001 Brain Res. pmid:11311871