stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Kiliç T et al. Fatty acid composition of seeds of some species of Nepeta L. 2007 Nat. Prod. Res. pmid:17487620
Shao Q et al. Comparison of neurofuzzy logic and decision trees in discovering knowledge from experimental data of an immediate release tablet formulation. 2007 Eur J Pharm Sci pmid:17459671
Kamilya T et al. Interaction and incorporation of ovalbumin with stearic acid monolayer: Langmuir-Blodgett film formation and deposition. 2007 Colloids Surf B Biointerfaces pmid:17418542
Liu J et al. Solid lipid nanoparticles loaded with insulin by sodium cholate-phosphatidylcholine-based mixed micelles: preparation and characterization. 2007 Int J Pharm pmid:17428627
Shao Q et al. Investigation of an artificial intelligence technology--Model trees. Novel applications for an immediate release tablet formulation database. 2007 Eur J Pharm Sci pmid:17452096
He X et al. Mechanistic study of the effect of roller compaction and lubricant on tablet mechanical strength. 2007 J Pharm Sci pmid:17455360
Fatouros DG et al. Clinical studies with oral lipid based formulations of poorly soluble compounds. 2007 Ther Clin Risk Manag pmid:18472981
Hamad ML et al. Drug product characterization by macropixel analysis of chemical images. 2007 J Pharm Sci pmid:17630646
Yuan H et al. Preparation and characteristics of nanostructured lipid carriers for control-releasing progesterone by melt-emulsification. 2007 Colloids Surf B Biointerfaces pmid:17656075
Kamilya T et al. Incorporation of ovalbumin within cationic octadecylamine monolayer and a comparative study with zwitterionic DPPC and anionic stearic acid monolayer. 2007 J Colloid Interface Sci pmid:17669414
Muzíková J and Nováková P A study of the properties of compacts from silicified microcrystalline celluloses. 2007 Drug Dev Ind Pharm pmid:17654026
Zhu S et al. Interaction of the acid soap of triethanolamine stearate and stearic acid with water. 2007 J Phys Chem B pmid:17266256
Desai D et al. Evaluation of selected micronized poloxamers as tablet lubricants. 2007 Drug Deliv pmid:17994358
Kambayashi Y et al. Various Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils via PKC Activation. 2007 J Clin Biochem Nutr pmid:18392102
Maghsoodi M et al. Improved compaction and packing properties of naproxen agglomerated crystals obtained by spherical crystallization technique. 2007 Drug Dev Ind Pharm pmid:18058318
Lumor SE et al. Synthesis and characterization of canola oil-stearic acid-based trans-free structured lipids for possible margarine application. 2007 J. Agric. Food Chem. pmid:18052237
Martino PD et al. The role of several l-HPCs in preventing tablet capping during direct compression of metronidazole. 2007 Drug Dev Ind Pharm pmid:18097804
Patel S et al. Lubrication potential of magnesium stearate studied on instrumented rotary tablet press. 2007 AAPS PharmSciTech pmid:18181549
You J et al. High cytotoxicity and resistant-cell reversal of novel paclitaxel loaded micelles by enhancing the molecular-target delivery of the drug. 2007 Nanotechnology pmid:20442465
Luo L et al. Polyoxyethylene 40 stearate modulates multidrug resistance and enhances antitumor activity of vinblastine sulfate. 2007 AAPS J pmid:18170979
Aziz HA et al. Solubility of core materials in aqueous polymeric solution effect on microencapsulation of curcumin. 2007 Drug Dev Ind Pharm pmid:18058323
Osman S et al. Tetrasphaera remsis sp. nov., isolated from the Regenerative Enclosed Life Support Module Simulator (REMS) air system. 2007 Int. J. Syst. Evol. Microbiol. pmid:18048719
Uzunović A and Vranić E Effect of magnesium stearate concentration on dissolution properties of ranitidine hydrochloride coated tablets. 2007 Bosn J Basic Med Sci pmid:17848158
Abdel-Hameid NA Protective role of dimethyl diphenyl bicarboxylate (DDB) against erythromycin induced hepatotoxicity in male rats. 2007 Toxicol In Vitro pmid:17267170
Yang DY et al. Detrimental effects of post-treatment with fatty acids on brain injury in ischemic rats. 2007 Neurotoxicology pmid:17854901
Ghosh SK et al. Characterization and cloning of a stearoyl/oleoyl specific fatty acyl-acyl carrier protein thioesterase from the seeds of Madhuca longifolia (latifolia). 2007 Plant Physiol. Biochem. pmid:17977002
Moore DJ et al. Infrared spectroscopy and differential scanning calorimetry studies of binary combinations of cis-6-octadecenoic acid and octadecanoic acid. 2007 Chem. Phys. Lipids pmid:17697674
Cakir T et al. Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. 2007 Theor Biol Med Model pmid:18070347
Zhang JQ et al. Preparation and characterization of solid lipid nanoparticles containing silibinin. 2007 Drug Deliv pmid:17701527
Miyazaki M et al. Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. 2007 Cell Metab. pmid:18054317
Matsuzaka T et al. Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. 2007 Nat. Med. pmid:17906635
Larsson KE et al. LysoPC acyltransferase/PC transacylase activities in plant plasma membrane and plasma membrane-associated endoplasmic reticulum. 2007 BMC Plant Biol. pmid:18045483
Nande VS et al. Sustained release microspheres of diclofenac sodium using PEGylated rosin derivatives. 2007 Drug Dev Ind Pharm pmid:17891576
Cunha-Filho MS et al. Compatibility of the antitumoral beta-lapachone with different solid dosage forms excipients. 2007 J Pharm Biomed Anal pmid:17890039
Kusano M et al. Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana. 2007 BMC Syst Biol pmid:18028551
Bhandari KH et al. Evaluation of physicochemical properties, skin permeation and accumulation profiles of ketorolac fatty ester prodrugs. 2007 Biol. Pharm. Bull. pmid:17978504
Chen Y et al. Formation of monodisperse and shape-controlled MnO nanocrystals in non-injection synthesis: self-focusing via ripening. 2007 J. Am. Chem. Soc. pmid:17696349
Krzeski P et al. Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study. 2007 Arthritis Res. Ther. pmid:17958901
Wang X et al. Phase characterization of indomethacin in binary solid dispersions with PVP VA64 or Myrj 52. 2007 Int J Pharm pmid:17604923
Walden M et al. The effect of ethanol on the release of opioids from oral prolonged-release preparations. 2007 Drug Dev Ind Pharm pmid:17882730
Dong J et al. Crystallization of silver carboxylates from sodium carboxylate mixtures. 2007 Langmuir pmid:17567157
Zhang YM et al. A Pseudomonas aeruginosa transcription factor that senses fatty acid structure. 2007 Mol. Microbiol. pmid:17877713
Raffin RP et al. Development of HPMC and Eudragit S100 blended microparticles containing sodium pantoprazole. 2007 Pharmazie pmid:17557744
Shen LJ and Wu FL Nanomedicines in renal transplant rejection--focus on sirolimus. 2007 Int J Nanomedicine pmid:17722509
Cieśliński H et al. A cold-adapted esterase from psychrotrophic Pseudoalteromas sp. strain 643A. 2007 Arch. Microbiol. pmid:17516048
Morkhade DM et al. PEGylated rosin derivatives: novel microencapsulating materials for sustained drug delivery. 2007 AAPS PharmSciTech pmid:17622122
Ramstedt M et al. Wet chemical silver treatment of endotracheal tubes to produce antibacterial surfaces. 2007 J. Biomed. Mater. Res. Part B Appl. Biomater. pmid:17385236
Mutalik S et al. Preparation, in vitro, preclinical and clinical evaluations of once daily sustained release tablets of aceclofenac. 2007 Arch. Pharm. Res. pmid:17366745
Otsuka M et al. Chemoinformetrical evaluation of dissolution property of indomethacin tablets by near-infrared spectroscopy. 2007 J Pharm Sci pmid:17238202
Feldkamp T et al. Alleviation of fatty acid and hypoxia-reoxygenation-induced proximal tubule deenergization by ADP/ATP carrier inhibition and glutamate. 2007 Am. J. Physiol. Renal Physiol. pmid:17244890
Mayer KM and Shanklin J Identification of amino acid residues involved in substrate specificity of plant acyl-ACP thioesterases using a bioinformatics-guided approach. 2007 BMC Plant Biol. pmid:17201914
Hefnawy MM et al. Direct enantiomeric resolution of betaxolol with application to analysis of pharmaceutical products. 2007 Anal Chem Insights pmid:19690633
Ruan HL et al. Ferulic acid esters from Euphorbia hylonoma. 2007 Fitoterapia pmid:17067756
Sephton MA et al. Biomedical and forensic applications of combined catalytic hydrogenation-stable isotope ratio analysis. 2007 Anal Chem Insights pmid:19662175
Nichols KK et al. Identification of fatty acids and fatty acid amides in human meibomian gland secretions. 2007 Invest. Ophthalmol. Vis. Sci. pmid:17197513
Zhao L et al. Non-destructive determination of metronidazole powder by using artificial neural networks on short-wavelength NIR spectroscopy. 2007 Spectrochim Acta A Mol Biomol Spectrosc pmid:16920000
Sampath H et al. Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat. 2007 J. Biol. Chem. pmid:17127673
Mahomed K et al. Erythrocyte omega-3, omega-6 and trans fatty acids in relation to risk of preeclampsia among women delivering at Harare Maternity Hospital, Zimbabwe. 2007 Physiol Res pmid:16497090
Sabin MA et al. Fasting nonesterified fatty acid profiles in childhood and their relationship with adiposity, insulin sensitivity, and lipid levels. 2007 Pediatrics pmid:18055661
Eltahlawy H et al. Evidence for two-step regulation of pheromone biosynthesis by the pheromone biosynthesis-activating neuropeptide in the moth Heliothis virescens. 2007 Arch. Insect Biochem. Physiol. pmid:17294424
Günther S et al. Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum. 2007 PLoS Pathog. pmid:18069893
Ishioka T et al. Infrared study on annealing effect on conformation of zinc stearate. 2007 Spectrochim Acta A Mol Biomol Spectrosc pmid:16875870
Forest PO et al. Influence of gradual introduction of hydrophobic groups (stearic acid) in denatured atelocollagen on fibroblasts behavior in vitro. 2007 J Biomed Mater Res A pmid:17133448
Wong HL et al. In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model. 2007 Eur J Pharm Biopharm pmid:17156986
Diakogiannaki E et al. Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells. 2007 J. Endocrinol. pmid:17641278
Davies PN et al. The determination of the mechanical strength of tablets of different shapes. 2007 Eur J Pharm Biopharm pmid:17329086
Maia MR et al. Metabolism of polyunsaturated fatty acids and their toxicity to the microflora of the rumen. 2007 Antonie Van Leeuwenhoek pmid:17072533
Petelska AD et al. Interfacial tension of the lipid membrane formed from lipid-fatty acid and lipid-amine systems. 2007 Bioelectrochemistry pmid:16713376
Uehara Y et al. Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element. 2007 Atherosclerosis pmid:16730733
Karupaiah T and Sundram K Effects of stereospecific positioning of fatty acids in triacylglycerol structures in native and randomized fats: a review of their nutritional implications. 2007 Nutr Metab (Lond) pmid:17625019
Cheng Y et al. Studies on the structure and miscibility of mixed Langmuir-Blodgett films of a double-armed dibenzo-18-crown-6 ether with stearic acid. 2007 J Colloid Interface Sci pmid:17207808
Malmberg P et al. Localization of lipids in the aortic wall with imaging TOF-SIMS. 2007 Biochim. Biophys. Acta pmid:17240191
Nolan LM et al. Combined effects of iontophoretic and chemical enhancement on drug delivery. II. Transport across human and murine skin. 2007 Int J Pharm pmid:17502130
Stimson L et al. Stearic acid spin labels in lipid bilayers: insight through atomistic simulations. 2007 J Phys Chem B pmid:17929861
Kositsawat J et al. The ratio of oleic-to-stearic acid in the prostate predicts biochemical failure after radical prostatectomy for localized prostate cancer. 2007 J. Urol. pmid:17936811
Egashira Y et al. Dietary protein level and dietary interaction affect quinolinic acid concentration in rats. 2007 Int J Vitam Nutr Res pmid:17896587
Paillard D et al. Quantification of ruminal Clostridium proteoclasticum by real-time PCR using a molecular beacon approach. 2007 J. Appl. Microbiol. pmid:17897229
Likitlersuang S et al. The effect of binary mixture composition and magnesium stearate concentration on the Hiestand Tableting Indices and other related mechanical properties. 2007 Pharm Dev Technol pmid:17963153
Wang ZJ et al. Stearic acid protects primary cultured cortical neurons against oxidative stress. 2007 Acta Pharmacol. Sin. pmid:17302992
Del Turco S et al. Parallel decrease of tissue factor surface exposure and increase of tissue factor microparticle release by the n-3 fatty acid docosahexaenoate in endothelial cells. 2007 Thromb. Haemost. pmid:17598015
Kanthimathi M and Dhathathreyan A Langmuir and Langmuir-Blodgett films of N-(4-octadecyloxy-2-hydroxybenzylidene) derivatives of amino acids. 2007 J Colloid Interface Sci pmid:17306822
Richter K et al. Localization of fatty acids with selective chain length by imaging time-of-flight secondary ion mass spectrometry. 2007 Microsc. Res. Tech. pmid:17393479
Simi CK and Emilia Abraham T Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery. 2007 Bioprocess Biosyst Eng pmid:17278045
Vighi E et al. Re-dispersible cationic solid lipid nanoparticles (SLNs) freeze-dried without cryoprotectors: characterization and ability to bind the pEGFP-plasmid. 2007 Eur J Pharm Biopharm pmid:17368876
Xu B and Yan B Photophysical properties of novel lanthanide (Tb3+, Dy3+, Eu3+) complexes with long chain para-carboxyphenol ester p-L-benzoate (L=dodecanoyloxy, myristoyloxy, palmitoyloxy and stearoyloxy). 2007 Spectrochim Acta A Mol Biomol Spectrosc pmid:16815090
Harrison V et al. Magnesium supplementation and perinatal hypoxia: outcome of a parallel group randomised trial in pregnancy. 2007 BJOG pmid:17578470
Shimizu K et al. Characterization of tableting using the OSDRC system. 2007 Pharm. Res. pmid:17554609
Berry SE et al. The solid fat content of stearic acid-rich fats determines their postprandial effects. 2007 Am. J. Clin. Nutr. pmid:17556683
Gorjão R et al. Regulation of interleukin-2 signaling by fatty acids in human lymphocytes. 2007 J. Lipid Res. pmid:17592174
Anjos JL et al. Effects of 1,8-cineole on the dynamics of lipids and proteins of stratum corneum. 2007 Int J Pharm pmid:17600646
Yang Y et al. Regulation of FAT/CD36 mRNA gene expression by long chain fatty acids in the differentiated 3T3-L1 cells. 2007 Pediatr. Surg. Int. pmid:17516074
Young PM et al. Effect of moisture on the compressibility and compactibility of sodium starch glycolate. 2007 Pharm Dev Technol pmid:17510894
Wei GH et al. Rhizobialide: a new stearolactone produced by Mesorhizobium sp. CCNWGX022, a rhizobial endophyte from Glycyrrhiza uralensis. 2007 Chem. Biodivers. pmid:17510984
Ando M et al. Development and evaluation of a novel dry-coated tablet technology for pellets as a substitute for the conventional encapsulation technology. 2007 Int J Pharm pmid:17223295
Bacher C et al. Improving the compaction properties of roller compacted calcium carbonate. 2007 Int J Pharm pmid:17582712
Dubrovin EV et al. Self-assembly effect during the adsorption of polynucleotides on stearic acid langmuir-blodgett monolayer. 2007 Biomacromolecules pmid:17583947
Wu H et al. Process analytical technology (PAT): effects of instrumental and compositional variables on terahertz spectral data quality to characterize pharmaceutical materials and tablets. 2007 Int J Pharm pmid:17590292
Jaimini M et al. Formulation and evaluation of famotidine floating tablets. 2007 Curr Drug Deliv pmid:17269917
Lee J Nanoscopic friction behavior of pharmaceutical materials. 2007 Int J Pharm pmid:17442509
Yuan H et al. Studies on oral absorption of stearic acid SLN by a novel fluorometric method. 2007 Colloids Surf B Biointerfaces pmid:17446050