| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Seizures | D012640 | 87 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gohel MC et al. | Modulation of venlafaxine hydrochloride release from press coated matrix tablet. | 2008 May-Jun | Indian J Pharm Sci | pmid:20046735 |
| Patel BP et al. | Formulation and evaluation of mouth dissolving tablets of cinnarizine. | 2010 | Indian J Pharm Sci | pmid:21218071 |
| Mazumder B et al. | Flow of Formulation Granules through a Conical Hopper. | 2008 | Indian J Pharm Sci | pmid:21369452 |
| Ranhotra HS and Sharma R | Polyunsaturated fatty acids inhibit mouse hepatic glucocorticoid receptor activation in vitro. | 2004 | Indian J. Biochem. Biophys. | pmid:22900281 |
| Carol D et al. | Synergistic effect of calcium stearate and photo treatment on the rate of biodegradation of low density polyethylene spent saline vials. | 2012 | Indian J. Exp. Biol. | pmid:22822530 |
| Hoppe JE and Haug A | Treatment and prevention of pertussis by antimicrobial agents (Part II). | 1988 May-Jun | Infection | pmid:3042626 |
| Schreiner A and Digranes A | Absorption of erythromycin stearate and enteric-coated erythromycin base after a single oral dose immediately before breakfast. | 1984 Sep-Oct | Infection | pmid:6511088 |
| Liu J et al. | Saturated fatty acids up-regulate COX-2 expression in prostate epithelial cells via toll-like receptor 4/NF-κB signaling. | 2014 | Inflammation | pmid:24221358 |
| Ali I and Steele JE | Evidence that free fatty acids in trophocytes of Periplaneta americana fat body may be regulated by the activity of phospholipase A2 and cyclooxygenase. | 1997 | Insect Biochem. Mol. Biol. | pmid:9404012 |
| Zhao CH et al. | Sex pheromone biosynthesis in the pine caterpillar moth, Dendrolimus punctatus (Lepidoptera: Lasiocampidae): pathways leading to Z5-monoene and 5,7-conjugated diene components. | 2004 | Insect Biochem. Mol. Biol. | pmid:14871622 |
| Foster SP and Anderson KG | Synthetic rates of key stored fatty acids in the biosynthesis of sex pheromone in the moth Heliothis virescens. | 2012 | Insect Biochem. Mol. Biol. | pmid:22982110 |
| Feng H et al. | Pharmacokinetics study of bio-adhesive tablet of Panax notoginseng saponins. | 2011 | Int Arch Med | pmid:21658246 |
| Hurko O et al. | Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. | 2010 | Int J Alzheimers Dis | pmid:20981353 |
| Rajendraprasad N et al. | Titrimetric and spectrophotometric assay of oxcarbazepine in pharmaceuticals using N-bromosuccinimide and bromopyrogallol red. | 2011 | Int J Anal Chem | pmid:21785594 |
| Raza A and Zia-Ul-Haq M | Application of Certain π-Acceptors for the Spectrophotometric Determination of Alendronate Sodium in Pharmaceutical Bulk and Dosage Forms. | 2011 | Int J Anal Chem | pmid:21760789 |
| Abdulrahman SA and Basavaiah K | Sensitive and selective spectrophotometric determination of gabapentin in capsules using two nitrophenols as chromogenic agents. | 2011 | Int J Anal Chem | pmid:21760787 |
| Zenita O and Basavaiah K | Utility of N-bromosuccinimide for the titrimetric and spectrophotometric determination of famotidine in pharmaceutical formulations. | 2011 | Int J Anal Chem | pmid:21760785 |
| Elokely KM et al. | Fluorescence Spectrometric Determination of Drugs Containing α-Methylene Sulfone/Sulfonamide Functional Groups Using N-Methylnicotinamide Chloride as a Fluorogenic Agent. | 2011 | Int J Anal Chem | pmid:21647288 |
| Mahmoud AM et al. | Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate. | 2009 | Int J Anal Chem | pmid:20140080 |
| Mahmoud AM | New sensitive kinetic spectrophotometric methods for determination of omeprazole in dosage forms. | 2009 | Int J Anal Chem | pmid:20140076 |
| Darwish IA et al. | New spectrophotometric and fluorimetric methods for determination of fluoxetine in pharmaceutical formulations. | 2009 | Int J Anal Chem | pmid:20107560 |
| Darwish IA et al. | Simple spectrophotometric method for determination of paroxetine in tablets using 1,2-naphthoquinone-4-sulphonate as a chromogenic reagent. | 2009 | Int J Anal Chem | pmid:20107559 |
| Keita Y et al. | Effect of free fatty acids on the binding kinetics at the benzodiazepine binding site of glycated human serum albumin. | 1993 | Int J Clin Pharmacol Ther Toxicol | pmid:7690351 |
| Habib NA et al. | Increased erythrocyte stearic acid desaturation in rats with chemically induced colorectal carcinomas. | 1987 | Int J Colorectal Dis | pmid:3598325 |
| Lodén M and Wessman C | Mascaras may cause irritant contact dermatitis. | 2002 | Int J Cosmet Sci | pmid:18498521 |
| Eccleston GM | The influence of fatty alcohols on the structure and stability of creams prepared with polyethylene glycol 1000 monostearate/fatty alcohols. | 1982 | Int J Cosmet Sci | pmid:19469959 |
| Pennick G et al. | Superior effect of isostearyl isostearate on improvement in stratum corneum water permeability barrier function as examined by the plastic occlusion stress test. | 2010 | Int J Cosmet Sci | pmid:20642769 |
| Gabirot M et al. | Differences in Chemical Sexual Signals May Promote Reproductive Isolation and Cryptic Speciation between Iberian Wall Lizard Populations. | 2012 | Int J Evol Biol | pmid:22288019 |
| Intorre F et al. | Fatty acid content of serum lipid fractions and blood lipids in normolipidaemic volunteers fed two types of cheese having different fat compositions: a pilot study. | 2013 | Int J Food Sci Nutr | pmid:22849318 |
| Intorre F et al. | Differential effect of cheese fatty acid composition on blood lipid profile and redox status in normolipidemic volunteers: a pilot study. | 2011 | Int J Food Sci Nutr | pmid:21591986 |
| Csallany AS et al. | Effect of high stearic acid containing fat on markers for in vivo lipid peroxidation. | 2005 | Int J Food Sci Nutr | pmid:16638661 |
| López-Cervantes J et al. | Effect of solvents and methods of stirring in extraction of lycopene, oleoresin and fatty acids from over-ripe tomato. | 2014 | Int J Food Sci Nutr | pmid:24111501 |
| Rastogi S et al. | Effect of treatment for Chlamydia trachomatis during pregnancy. | 2003 | Int J Gynaecol Obstet | pmid:12566185 |
| Ohiri RC and Bassey EE | Gas Chromatography-Mass Spectrometry Analysis of Constituent Oil from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), from Nigeria. | 2016 | Int J Med Mushrooms | pmid:27481303 |
| Celleno L et al. | A Dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women. | 2007 | Int J Med Sci | pmid:17299581 |
| Kwon Y et al. | Arabidopsis serine decarboxylase mutants implicate the roles of ethanolamine in plant growth and development. | 2012 | Int J Mol Sci | pmid:22489147 |
| Tong M et al. | The effect of Zn-Al-hydrotalcites composited with calcium stearate and β-diketone on the thermal stability of PVC. | 2011 | Int J Mol Sci | pmid:21673921 |
| Souza AF et al. | Waste Soybean Oil and Corn Steep Liquor as Economic Substrates for Bioemulsifier and Biodiesel Production by Candida lipolytica UCP 0998. | 2016 | Int J Mol Sci | pmid:27669227 |
| Šrámek J et al. | p38 MAPK Is Activated but Does Not Play a Key Role during Apoptosis Induction by Saturated Fatty Acid in Human Pancreatic β-Cells. | 2016 | Int J Mol Sci | pmid:26861294 |
| Kajiro H et al. | Flexible two-dimensional square-grid coordination polymers: structures and functions. | 2010 | Int J Mol Sci | pmid:21152303 |
| Kanjanavas P et al. | Purification and characterization of organic solvent and detergent tolerant lipase from thermotolerant Bacillus sp. RN2. | 2010 | Int J Mol Sci | pmid:21152301 |
| Li N et al. | Function of SREBP1 in the milk fat synthesis of dairy cow mammary epithelial cells. | 2014 | Int J Mol Sci | pmid:25250914 |
| Camacho-Chab JC et al. | Emulsifying activity and stability of a non-toxic bioemulsifier synthesized by Microbacterium sp. MC3B-10. | 2013 | Int J Mol Sci | pmid:24065097 |
| Cheng YY et al. | A novel cold-adapted lipase from Sorangium cellulosum strain So0157-2: gene cloning, expression, and enzymatic characterization. | 2011 | Int J Mol Sci | pmid:22072918 |
| Eili M et al. | Degradability enhancement of poly(lactic acid) by stearate-Zn(3)Al LDH nanolayers. | 2012 | Int J Mol Sci | pmid:22942682 |
| Marvey BB | Extrudate versus powder silica alumina as support for Re₂O₇ catalyst in the metathesis of seed oil-derivatives - a comparison. | 2009 | Int J Mol Sci | pmid:19333442 |
| Ling XY et al. | Supramolecular layer-by-layer assembly of 3D multicomponent nanostructures via multivalent molecular recognition. | 2008 | Int J Mol Sci | pmid:19325764 |
| Lan DM et al. | A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. | 2011 | Int J Mol Sci | pmid:21747717 |
| Salem HF | Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats. | 2010 | Int J Nanomedicine | pmid:21187946 |
| Wang K et al. | Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. | 2011 | Int J Nanomedicine | pmid:22238509 |
| Grassi G et al. | Propaedeutic study for the delivery of nucleic acid-based molecules from PLGA microparticles and stearic acid nanoparticles. | 2006 | Int J Nanomedicine | pmid:17722283 |
| Du YZ et al. | Receptor-mediated gene delivery by folic acid-modified stearic acid-grafted chitosan micelles. | 2011 | Int J Nanomedicine | pmid:21845046 |
| Xie YT et al. | Brain-targeting study of stearic acid-grafted chitosan micelle drug-delivery system. | 2012 | Int J Nanomedicine | pmid:22802685 |
| Shen LJ and Wu FL | Nanomedicines in renal transplant rejection--focus on sirolimus. | 2007 | Int J Nanomedicine | pmid:17722509 |
| You JO et al. | Incorporation of quantum dots on virus in polycationic solution. | 2006 | Int J Nanomedicine | pmid:17722262 |
| Zhang ZH et al. | Solid lipid nanoparticles modified with stearic acid-octaarginine for oral administration of insulin. | 2012 | Int J Nanomedicine | pmid:22848162 |
| Lin YK et al. | Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery. | 2010 | Int J Nanomedicine | pmid:20309398 |
| Almeida CP et al. | Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake. | 2010 | Int J Nanomedicine | pmid:20957219 |
| Almer G et al. | Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques. | 2011 | Int J Nanomedicine | pmid:21753879 |
| Li FQ et al. | A novel spray-dried nanoparticles-in-microparticles system for formulating scopolamine hydrobromide into orally disintegrating tablets. | 2011 | Int J Nanomedicine | pmid:21720502 |
| Salem H et al. | Nanosized rods agglomerates as a new approach for formulation of a dry powder inhaler. | 2011 | Int J Nanomedicine | pmid:21383856 |
| Yuan H et al. | Preparation and evaluation of SiO2-deposited stearic acid-g-chitosan nanoparticles for doxorubicin delivery. | 2012 | Int J Nanomedicine | pmid:23055724 |
| Rehman M et al. | Solid and liquid lipid-based binary solid lipid nanoparticles of diacerein: in vitro evaluation of sustained release, simultaneous loading of gold nanoparticles, and potential thermoresponsive behavior. | 2015 | Int J Nanomedicine | pmid:25897224 |
| Chen FY et al. | TNYL peptide functional chitosan-g-stearate conjugate micelles for tumor specific targeting. | 2014 | Int J Nanomedicine | pmid:25298734 |
| Chen Y et al. | Stepwise encapsulation and controlled two-stage release system for cis-Diamminediiodoplatinum. | 2014 | Int J Nanomedicine | pmid:25061294 |
| Yao JJ et al. | Efficient gene delivery system mediated by cis-aconitate-modified chitosan-g-stearic acid micelles. | 2014 | Int J Nanomedicine | pmid:24971010 |
| Vadakkan MV et al. | Dry powder cationic lipopolymeric nanomicelle inhalation for targeted delivery of antitubercular drug to alveolar macrophage. | 2013 | Int J Nanomedicine | pmid:23990716 |
| Xu Y et al. | Carbon-covered magnetic nanomaterials and their application for the thermolysis of cancer cells. | 2010 | Int J Nanomedicine | pmid:20463932 |
| Yuan M et al. | Effect of A-317491 delivered by glycolipid-like polymer micelles on endometriosis pain. | 2017 | Int J Nanomedicine | pmid:29184406 |
| Farboud ES et al. | Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies. | 2011 | Int J Nanomedicine | pmid:21674018 |
| Abdulrazik M et al. | Formulation for slow release of oral radiation-protection drugs. | 1984 | Int J Nucl Med Biol | pmid:6610665 |
| Vögler O et al. | Structure-effect relation of C18 long-chain fatty acids in the reduction of body weight in rats. | 2008 | Int J Obes (Lond) | pmid:18059405 |
| McGimpsey JG et al. | Comparison of serum erythromycin concentration following administration of 100 mg erythromycin ethyl succinate intramuscularly and 500 mg erythromycin stearate orally. | 1981 | Int J Oral Surg | pmid:6807878 |
| Zhou QT et al. | Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties. | 2011 | Int J Pharm | pmid:21527321 |
| Badal Tejedor M et al. | Tablet mechanics depend on nano and micro scale adhesion, lubrication and structure. | 2015 | Int J Pharm | pmid:25841569 |
| Wissing S et al. | An investigation into the use of stepwise isothermal high sensitivity DSC as a means of detecting drug-excipient incompatibility. | 2000 | Int J Pharm | pmid:10802407 |
| Raith K et al. | Towards a molecular characterization of pharmaceutical excipients: mass spectrometric studies of ethoxylated surfactants. | 2006 | Int J Pharm | pmid:16730931 |
| Tay T et al. | Magnesium stearate increases salbutamol sulphate dispersion: what is the mechanism? | 2010 | Int J Pharm | pmid:19748561 |
| Fujii M et al. | Preparation, characterization, and tableting of a solid dispersion of indomethacin with crospovidone. | 2005 | Int J Pharm | pmid:15778052 |
| Saeedi Vahdat A et al. | Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets. | 2013 | Int J Pharm | pmid:23820132 |
| Zhang Q et al. | Studies on the cyclosporin A loaded stearic acid nanoparticles. | 2000 | Int J Pharm | pmid:10867245 |
| Li L et al. | Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film. | 2013 | Int J Pharm | pmid:23624081 |
| Neutsch L et al. | UPEC biomimickry at the urothelial barrier: lectin-functionalized PLGA microparticles for improved intravesical chemotherapy. | 2013 | Int J Pharm | pmid:23628404 |
| Nakagawa H et al. | Real-time monitoring of lubrication properties of magnesium stearate using NIR spectrometer and thermal effusivity sensor. | 2013 | Int J Pharm | pmid:23174413 |
| McDaid FM et al. | Further investigations into the use of high sensitivity differential scanning calorimetry as a means of predicting drug-excipient interactions. | 2003 | Int J Pharm | pmid:12550799 |
| Rege PR et al. | Spray-dried chitinosans. Part II: in vitro drug release from tablets made from spray-dried chitinosans. | 2003 | Int J Pharm | pmid:12550780 |
| Eliasen H et al. | Growth mechanisms in melt agglomeration with a low viscosity binder. | 1999 | Int J Pharm | pmid:10486433 |
| Planinsek O et al. | Surface analysis of powder binary mixtures with ATR FTIR spectroscopy. | 2006 | Int J Pharm | pmid:16730933 |
| Wahl PR et al. | Continuous monitoring of API content, API distribution and crushing strength after tableting via near-infrared chemical imaging. | 2017 | Int J Pharm | pmid:27923700 |
| Maretti E et al. | Inhaled Solid Lipid Microparticles to target alveolar macrophages for tuberculosis. | 2014 | Int J Pharm | pmid:24374224 |
| Samanta AK et al. | Energy-based analysis of cone milling process for the comminution of roller compacted flakes. | 2014 | Int J Pharm | pmid:24374608 |
| Xue J et al. | A novel and organic solvent-free preparation of solid lipid nanoparticles using natural biopolymers as emulsifier and stabilizer. | 2017 | Int J Pharm | pmid:28802794 |
| Lapham DP and Lapham JL | Gas adsorption on commercial magnesium stearate: Effects of degassing conditions on nitrogen BET surface area and isotherm characteristics. | 2017 | Int J Pharm | pmid:28779986 |
| Nagy B et al. | In-line Raman spectroscopic monitoring and feedback control of a continuous twin-screw pharmaceutical powder blending and tableting process. | 2017 | Int J Pharm | pmid:28723408 |
| Miguélez-Morán AM et al. | The effect of lubrication on density distributions of roller compacted ribbons. | 2008 | Int J Pharm | pmid:18602976 |
| Schrank S et al. | Pore blocking: An innovative formulation strategy for the design of alcohol resistant multi-particulate dosage forms. | 2016 | Int J Pharm | pmid:27282540 |
| Andrès C et al. | On the difficulty of assessing the specific surface area of magnesium stearate. | 2001 | Int J Pharm | pmid:11337159 |
| Fukui E et al. | Effect of magnesium stearate or calcium stearate as additives on dissolution profiles of diltiazem hydrochloride from press-coated tablets with hydroxypropylmethylcellulose acetate succinate in the outer shell. | 2001 | Int J Pharm | pmid:11274815 |
| Anjos JL et al. | Effects of 1,8-cineole on the dynamics of lipids and proteins of stratum corneum. | 2007 | Int J Pharm | pmid:17600646 |
| Guillon A et al. | Pulmonary delivery of dry powders to rats: tolerability limits of an intra-tracheal administration model. | 2012 | Int J Pharm | pmid:22609125 |