stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Pohl EE et al. Changes of intrinsic membrane potentials induced by flip-flop of long-chain fatty acids. 2000 Biochemistry pmid:10677234
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Saito A et al. Effects of capsaicin on biliary free fatty acids in rats. 2000 Int J Vitam Nutr Res pmid:10683757
Chang RK and Hussain MA Consolidation behavior of an experimental, cross-linked polyalkyl ammonium polymer. 2000 Drug Dev Ind Pharm pmid:10697761
Willie BM et al. Elemental and morphological identification of third-body particulate and calcium stearate inclusions in polyethylene components. 2000 J. Biomed. Mater. Res. pmid:10713559
Jenkins TC Feeding oleamide to lactating Jersey cows 1. Effects on lactation performance and milk fatty acid composition. 2000 J. Dairy Sci. pmid:10714869
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Shiromani PK and Clair J Statistical comparison of high-shear versus low-shear granulation using a common formulation. 2000 Drug Dev Ind Pharm pmid:10738654
el-Mahdi IM and Deasy PB Tableting of coated ketoprofen pellets. 2000 Mar-Apr J Microencapsul pmid:10738689
Muller D et al. Niosomes as carriers of radiopaque contrast agents for X-ray imaging. 2000 Mar-Apr J Microencapsul pmid:10738698
Florin-Christensen J et al. Phosphatidylcholine formation is the predominant lipid biosynthetic event in the hemoparasite Babesia bovis. 2000 Mol. Biochem. Parasitol. pmid:10743618
Plötz BM et al. Characterization of a novel lipid A containing D-galacturonic acid that replaces phosphate residues. The structure of the lipid a of the lipopolysaccharide from the hyperthermophilic bacterium Aquifex pyrophilus. 2000 J. Biol. Chem. pmid:10753930
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Swaminathan V and Kildsig DO The effect of particle morphology on the physical stability of pharmaceutical powder mixtures: the effect of surface roughness of the carrier on the stability of ordered mixtures. 2000 Drug Dev Ind Pharm pmid:10769777
Schmider W et al. Transport of heptafluorostearate across model membranes. Membrane transport of long-chain fatty acid anions I. 2000 J. Lipid Res. pmid:10787438
Wissing S et al. An investigation into the use of stepwise isothermal high sensitivity DSC as a means of detecting drug-excipient incompatibility. 2000 Int J Pharm pmid:10802407
Min Y et al. Pregnancy reduces arachidonic and docosahexaenoic in plasma triacylglycerols of Korean women. 2000 Int J Vitam Nutr Res pmid:10804459
Pignatello R et al. In vitro release kinetics of Tolmetin from tabletted Eudragit microparticles. 2000 May-Jun J Microencapsul pmid:10819424
Tsuda K et al. Role of insulin in the regulation of membrane fluidity of erythrocytes in essential hypertension: an electron paramagnetic resonance investigation. 2000 Am. J. Hypertens. pmid:10821339
Aguilella VM et al. Double layer potential and degree of dissociation in charged lipid monolayers. 2000 Chem. Phys. Lipids pmid:10823470
Messier AM and Bizzozero OA Conserved fatty acid composition of proteolipid protein during brain development and in myelin subfractions. 2000 Neurochem. Res. pmid:10823577
Bessesen DH et al. Trafficking of dietary oleic, linolenic, and stearic acids in fasted or fed lean rats. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10827016
Ehinger AM and Kietzmann M Tissue distribution of oxacillin and ampicillin in the isolated perfused bovine udder. 2000 J Vet Med A Physiol Pathol Clin Med pmid:10842465
Richieri GV et al. Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions. 2000 Biochemistry pmid:10852718
Zhang Q et al. Studies on the cyclosporin A loaded stearic acid nanoparticles. 2000 Int J Pharm pmid:10867245
Stanley JC VAT and fat. Taxing single nutrient is dangerous. 2000 BMJ pmid:10877557
Robson H et al. An investigation into the release of cefuroxime axetil from taste-masked stearic acid microspheres. III. The use of DSC and HSDSC as means of characterising the interaction of the microspheres with buffered media. 2000 Int J Pharm pmid:10878327
Schweigert FJ and Bok V Vitamin A in blood plasma and urine of dogs is affected by the dietary level of vitamin A. 2000 Int J Vitam Nutr Res pmid:10883401
Le Hénaff M and Fontenelle C Chemical analysis of processing of spiralin, the major lipoprotein of Spiroplasma melliferum. 2000 May-Jun Arch. Microbiol. pmid:10896212
Bogataj M et al. The influence of magnesium stearate on the characteristics of mucoadhesive microspheres. 2000 Jul-Aug J Microencapsul pmid:10898089
Enjalbert F et al. Effects of duodenal infusions of palmitic, stearic, or oleic acids on milk composition and physical properties of butter. 2000 J. Dairy Sci. pmid:10908048
Russo LI and Ghaly ES Drug release from Carbomer 934 matrices. 2000 P R Health Sci J pmid:10909708
Vashchuk VV and Vashchuk VV [The use of the catalase P-47 preparation for treating long-term nonhealing wounds and trophic ulcers]. 1993 Klin Khir pmid:10912018
Lee WN et al. Loss of regulation of lipogenesis in the Zucker diabetic (ZDF) rat. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10913044
Siaan M et al. Influence of Avicel PH-301 on the compressibility of alpha-methyldopa and phenobarbitone in direct compression. 2000 Drug Dev Ind Pharm pmid:10914328
Robles Valderrama E et al. [Application of gas chromatography in the identification of Enterobacter cloacae, Enterobacter aerogenes, and Enterobacter agglomerans]. 1999 Jan-Mar Rev. Latinoam. Microbiol. pmid:10932747
Wardrop J et al. Determination of erythromycin and related substances in enteric-coated tablet formulations by reversed-phase liquid chromatography. 2000 J Pharm Sci pmid:10944374
Khalil MH et al. Topical application of docosanol- or stearic acid-containing creams reduces severity of phenol burn wounds in mice. 2000 Contact Derm. pmid:10945745
Kim YC et al. Differential regulation of the stearoyl-CoA desaturase genes by thiazolidinediones in 3T3-L1 adipocytes. 2000 J. Lipid Res. pmid:10946019
Ishioka T et al. Infrared and XAFS study on structure and transition behavior of zinc stearate. 2000 Spectrochim Acta A Mol Biomol Spectrosc pmid:10952134
Muzík M and Muzíková J [Effect of magnesium stearate on internal failure of Avicel PH 101 tablets]. 2000 Ceska Slov Farm pmid:10953461
Hennig B et al. Fatty acid-mediated activation of vascular endothelial cells. 2000 Metab. Clin. Exp. pmid:10954018
Hatipoglu ON and Tasan Y A comparative efficacy and safety study of clarithromycin, roxithromycin and erythromycin stearate in mild pneumonia. 2000 Yonsei Med. J. pmid:10957888
Hattori Y et al. Role of phospholipase A2 in cholesterol gallstone formation is associated with biliary phospholipid species selection at the site of hepatic excretion: indirect evidence. 2000 Dig. Dis. Sci. pmid:10961723
Broderick PA et al. Monoamine neurotransmitters in resected hippocampal subparcellations from neocortical and mesial temporal lobe epilepsy patients: in situ microvoltammetric studies. 2000 Brain Res. pmid:10996135
Willie BM et al. Possible explanation for the white band artifact seen in clinically retrieved polyethylene tibial components. 2000 J. Biomed. Mater. Res. pmid:11007625
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Mossab A et al. Utilization of soybean oil and tallow in young turkeys compared with young chickens. 2000 Poult. Sci. pmid:11020079
Engler MM et al. Dietary docosahexaenoic acid affects stearic acid desaturation in spontaneously hypertensive rats. 2000 Lipids pmid:11026622
Miersch O and Wasternack C Octadecanoid and jasmonate signaling in tomato (Lycopersicon esculentum Mill.) leaves: endogenous jasmonates do not induce jasmonate biosynthesis. 2000 Biol. Chem. pmid:11030429