stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Pujeri SS et al. Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. 2012 Jan-Mar Sci Pharm pmid:22396908
Kalm O et al. Erythromycin stearate in acute maxillary sinusitis. 1975 Scand. J. Infect. Dis. pmid:241119
Heimdahl A and Nord CE Influence of erythromycin on the normal human flora and colonization of the oral cavity, throat and colon. 1982 Scand. J. Infect. Dis. pmid:7071527
Eriksson M et al. Absorption of erythromycin from pediatric suspension in infants and children. 1981 Scand. J. Infect. Dis. pmid:7313575
Kaukoranta-Tolvanen SS et al. Effect of erythromycin acistrate and erythromycin stearate on human colonic microflora. 1989 Scand. J. Infect. Dis. pmid:2617212
Woldseth B et al. Monounsaturated trans fatty acids, elaidic acid and trans-vaccenic acid, metabolism and incorporation in phospholipid molecular species in hepatocytes. 1998 Scand. J. Clin. Lab. Invest. pmid:10088200
FARSTAD M DETERMINATION OF FATTY ACIDS IN CEREBROSPINAL FLUID. II. QUALITATIVE AND QUANTITATIVE STUDIES BY A COMBINATION OF ALKALI TITRATION AND GAS CHROMATOGRAPHY. 1964 Scand. J. Clin. Lab. Invest. pmid:14161847
Tola S Occupational lead exposure in Finland. IV. The polyvinyl chloride plastic industry. 1975 Scand J Work Environ Health pmid:1228897
Cavalleri A and Minoia C Lead level of whole blood and plasma in workers exposed to lead stearate. 1987 Scand J Work Environ Health pmid:3616550
Fernandes AC et al. Enhancement of human polymorphonuclear leucocyte motility by erythromycin in vitro and in vivo. 1984 S. Afr. Med. J. pmid:6463793
Ras GJ et al. Chemoprophylaxis with erythromycin stearate or amoxycillin in patients with chronic bronchitis--effects on cellular and humoral immune functions. 1984 Dec 22-29 S. Afr. Med. J. pmid:6515508
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Tönges L et al. Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons. 2006 RNA pmid:16699166
CALI G et al. [GAS CHROMATOGRAPHY RESEARCH ON THE FATTY ACIDS OF HUMAN ADIPOSE TISSUE]. 1963 Ric Sci 2 Ser Pt 2 Rend B pmid:14123061
Robles Valderrama E et al. [Application of gas chromatography in the identification of Enterobacter cloacae, Enterobacter aerogenes, and Enterobacter agglomerans]. 1999 Jan-Mar Rev. Latinoam. Microbiol. pmid:10932747
Uribe WR Yaws in Colombia. 1985 May-Jun Rev. Infect. Dis. pmid:4012172
Willcox RR Mass treatment campaigns against the endemic treponematoses. 1985 May-Jun Rev. Infect. Dis. pmid:4012173
Brown ST Therapy for nonvenereal treponematoses: review of the efficacy of penicillin and consideration of alternatives. 1985 May-Jun Rev. Infect. Dis. pmid:4012176
Zerbini E et al. [Characterization of fatty acids and mycolic acid degradation products in mycobacterial species of major incidence in Argentina]. 1997 Oct-Dec Rev. Argent. Microbiol. pmid:9472140
Daubresse JC [Atherosclerosis and nutrition]. 2000 Rev Med Brux pmid:11068494
BIOZZI G et al. [Stimulation and depression of the phagocytic function of the reticuloendothelial system by lipid emulsions. Relation to some immunological phenomena]. 1963 Rev Fr Etud Clin Biol pmid:13968394
Thompson GE and Darling KF The hepatic uptake of individual free fatty acids in sheep during noradrenaline infusion. 1975 Res. Vet. Sci. pmid:1144925
Grabowski A et al. Characterization of long-chain fatty-acid-degrading syntrophic associations from a biodegraded oil reservoir. 2005 Res. Microbiol. pmid:15939576
Wosilait WD and Ryan MP The effects of oleic acid, tolbutamide, and oxyphenbutazone on the binding of warfarin by human serum albumin. 1979 Res. Commun. Chem. Pathol. Pharmacol. pmid:504792
Kim JY et al. Lipid and fatty acid analysis of fresh and frozen-thawed immature and in vitro matured bovine oocytes. 2001 Reproduction pmid:11425337
Bender K et al. Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. 2010 Reproduction pmid:20385782
Van Hoeck V et al. Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights. 2013 Reproduction pmid:23108110
Waterhouse KE et al. Within and between breed differences in freezing tolerance and plasma membrane fatty acid composition of boar sperm. 2006 Reproduction pmid:16672353
Leroy JL et al. Non-esterified fatty acids in follicular fluid of dairy cows and their effect on developmental capacity of bovine oocytes in vitro. 2005 Reproduction pmid:16183866
Van Hoeck V et al. Interaction between differential gene expression profile and phenotype in bovine blastocysts originating from oocytes exposed to elevated non-esterified fatty acid concentrations. 2015 Reprod. Fertil. Dev. pmid:24360349
Shehab-El-Deen MA et al. Cryotolerance of bovine blastocysts is affected by oocyte maturation in media containing palmitic or stearic acid. 2009 Reprod. Domest. Anim. pmid:18992093
Renaville B et al. Plasma and follicular fluid fatty acid profiles in dairy cows. 2010 Reprod. Domest. Anim. pmid:19055554
Craig OE et al. Distinguishing wild ruminant lipids by gas chromatography/combustion/isotope ratio mass spectrometry. 2012 Rapid Commun. Mass Spectrom. pmid:22956328
Liu Y et al. Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. 2011 Rapid Commun. Mass Spectrom. pmid:22006384
Xue R et al. A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18767022
Loutelier-Bourhis C et al. Mechanistic study of maleic anhydride grafting onto fatty double bonds using mass spectrometry. 2012 Rapid Commun. Mass Spectrom. pmid:22555920
MIRAS CJ et al. LIPID BIOSYNTHESIS BY HUMAN BONE MARROW CELL CULTURES AND GAMMA RADIATION. 1964 Radiat. Res. pmid:14201876
Yamamoto O Radiation-induced crosslinks between carboxylic acids and compounds of biological interest. 1986 Radiat. Res. pmid:3952268
SNYDER F and WRIGHT R EFFECT OF LOCALIZED IRRADIATION ON THE METABOLISM OF BONE-MARROW LIPIDS. 1965 Radiat. Res. pmid:14295131
Chitapanarux I et al. Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. 2010 Radiat Oncol pmid:20444243
McNamara RK et al. Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder. 2008 Psychiatry Res pmid:18715653
Murphy DJ The extracellular pollen coat in members of the Brassicaceae: composition, biosynthesis, and functions in pollination. 2006 Protoplasma pmid:16937052
Evoli S et al. Molecular simulations of β-lactoglobulin complexed with fatty acids reveal the structural basis of ligand affinity to internal and possible external binding sites. 2014 Proteins pmid:24916607
Cheng HC et al. Lipid binding in rice nonspecific lipid transfer protein-1 complexes from Oryza sativa. 2004 Protein Sci. pmid:15295114
Watanabe L et al. Initiating structural studies of Lys49-PLA2 homologues complexed with an anionic detergent, a fatty acid and a natural lipid. 2003 Protein Pept. Lett. pmid:14561144
Fujimoto Y et al. Stearic acid potently modulates the activity of cyclooxygenase-1, but not cyclooxygenase-2, in the form of its CoA ester. 2008 Prostaglandins Leukot. Essent. Fatty Acids pmid:18083017
Cunnane SC Metabolism of polyunsaturated fatty acids and ketogenesis: an emerging connection. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:14769482
Alava MA et al. Fatty acid desaturation: effect of alphafetoprotein on alpha-linolenic acid conversion by fetal rat hepatocytes. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10359023
Barber E et al. Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:24012207
Sakuma S et al. The effects of fatty acyl CoA esters on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11161586