stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Avila P et al. Which salt of erythromycin is most hepatotoxic? 1988 Lancet pmid:2896928
Jones RE and Plymate SR Evidence for the regulation of fatty acid utilization in human sperm by docosahexaenoic acid. 1988 Biol. Reprod. pmid:2905175
Periquet B et al. Fatty acid composition and kinetic behaviour of liver retinyl esters in vitamin A sufficient and deficient rats. 1988 Clin. Chim. Acta pmid:3370842
Brodersen R et al. Palmitate binding to serum albumin, measured by rate of dialysis. 1988 Eur. J. Biochem. pmid:3371363
Slinger AJ and Isaac RE Synthesis of apolar ecdysone esters by ovaries of the cockroach Periplaneta americana. 1988 Gen. Comp. Endocrinol. pmid:3371652
Roberts L Beef and chocolate: a partial reprieve. 1988 Science pmid:3375809
Salo OP et al. Efficacy and tolerability of erythromycin acistrate and erythromycin stearate in acute skin infections of patients with atopic eczema. 1988 J. Antimicrob. Chemother. pmid:3391871
Rostila T et al. Erythromycin acistrate and erythromycin stearate in the treatment of non-gonococcal urethritis. 1988 J. Antimicrob. Chemother. pmid:3391873
Männistö PT et al. Fate of single oral doses of erythromycin acistrate, erythromycin stearate and pelleted erythromycin base analysed by mass-spectrometry in plasma of healthy human volunteers. 1988 J. Antimicrob. Chemother. pmid:3391874
Savolainen S et al. Tonsillar penetration of erythromycin and its 2'-acetyl ester in patients with chronic tonsillitis. 1988 J. Antimicrob. Chemother. pmid:3391878
Horváth LI et al. Exchange rates at the lipid-protein interface of myelin proteolipid protein studied by spin-label electron spin resonance. 1988 Biochemistry pmid:2450570
Loscalzo J et al. Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells. 1987 Sep-Oct Arteriosclerosis pmid:3675304
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Kringsholm B and Christoffersen P The nature and the occurrence of birefringent material in different organs in fatal drug addiction. 1987 May-Jun Forensic Sci. Int. pmid:3036675
Udod VM et al. [Microbial breakdown of stearox-6 and a study of the genetic determination of the nature of the degradative activity]. 1987 May-Jun Mikrobiol. Zh. pmid:3150493
Fatemi SH et al. The glycophospholipid anchor of Thy-1. Biosynthetic labeling experiments with wild-type and class E Thy-1 negative lymphomas. 1987 J. Biol. Chem. pmid:2881925
Nakanishi H et al. Comparative studies on additive effects of sodium dodecylbenzensulfonate and sodium stearate on uptake of chemicals by willow shiner (Gnathopogon caerulescens). 1987 Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. pmid:2882933
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Swendsen CL et al. Human neutrophils incorporate arachidonic acid and saturated fatty acids into separate molecular species of phospholipids. 1987 Biochim. Biophys. Acta pmid:3105590
DeGeorge JJ et al. Acetylcholine stimulates selective liberation and re-esterification of arachidonate and accumulation of inositol phosphates and glycerophosphoinositol in C62B glioma cells. 1987 J. Biol. Chem. pmid:3110145
Morse DR et al. Infectious flare-ups and serious sequelae following endodontic treatment: a prospective randomized trial on efficacy of antibiotic prophylaxis in cases of asymptomatic pulpal-periapical lesions. 1987 Oral Surg. Oral Med. Oral Pathol. pmid:3112672
Crost S et al. Hormonal effects on mitochondrial respiration: potential role of endogenous lipolytic activities. 1987 Arch. Biochem. Biophys. pmid:3113334
Halát G et al. Effects of incomplete ischemia and subsequent recirculation on free palmitate, stearate, oleate and arachidonate levels in lumbar and cervical spinal cord of rabbit. 1987 Gen. Physiol. Biophys. pmid:3117617
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Taylor AJ et al. An alternative explanation for the changes in erythrocyte fatty acids observed in diabetes mellitus. 1987 Clin. Chem. pmid:3119255
Shanson DC Antibiotic prophylaxis of infective endocarditis in the United Kingdom and Europe. 1987 J. Antimicrob. Chemother. pmid:3119557
Feix JB et al. Interactions of 14N:15N stearic acid spin-label pairs: effects of host lipid alkyl chain length and unsaturation. 1987 Biochemistry pmid:2820479
Rhoads DE et al. Metabolism of saturated fatty acids by Paramecium tetraurelia. 1987 J. Lipid Res. pmid:3430068
Tonnet ML and Green AG Characterization of the seed and leaf lipids of high and low linolenic acid flax genotypes. 1987 Arch. Biochem. Biophys. pmid:3813554
Ong DE et al. Acyl-CoA-independent esterification of retinol bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine. 1987 J. Biol. Chem. pmid:3818619
Albertini G et al. Studies of structural modifications induced by gamma-irradiation in distearoylphosphatidylcholine liposomes. 1987 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:3496306
Carter BL et al. Gastrointestinal side effects with erythromycin preparations. 1987 Drug Intell Clin Pharm pmid:3498618
Seifert R et al. Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. 1987 Biochem. Biophys. Res. Commun. pmid:3426598
Bos CE et al. Native starch in tablet formulations: properties on compaction. 1987 Pharm Weekbl Sci pmid:3432037
Bridges CD et al. Rhodopsin, vitamin A, and interstitial retinol-binding protein in the rd chicken. 1987 Invest. Ophthalmol. Vis. Sci. pmid:3557867
Hope MJ and Cullis PR Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. 1987 J. Biol. Chem. pmid:3558410
Husebye ES and Flatmark T Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. 1987 Biochim. Biophys. Acta pmid:3607074
Cavalleri A and Minoia C Lead level of whole blood and plasma in workers exposed to lead stearate. 1987 Scand J Work Environ Health pmid:3616550
Seimiya T et al. Effects of composition and molecular packing on ionic properties of lipid monolayer having both cationic and anionic head groups. 1987 Chem. Phys. Lipids pmid:3621383
Salminen S and Salminen E Urinary excretion of orally administered oxalic acid in MYRJ 45-treated NMRI mice. 1987 Toxicol. Lett. pmid:3590233
Masuzawa Y et al. Distribution of dietary trans-octadecenoate among acyl-CoA and other lipid fractions of rat liver and heart. 1987 Biochim. Biophys. Acta pmid:3593750
Kolesnick RN and Paley AE 1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action. 1987 J. Biol. Chem. pmid:3597411
Habib NA et al. Increased erythrocyte stearic acid desaturation in rats with chemically induced colorectal carcinomas. 1987 Int J Colorectal Dis pmid:3598325
Pyörälä S Effect of some vehicles used in intramammary mastitis preparations on inflammation indicators in milk. 1987 J. Vet. Pharmacol. Ther. pmid:3656512
Emken EA et al. Metabolism in humans of cis-12,trans-15-octadecadienoic acid relative to palmitic, stearic, oleic and linoleic acids. 1987 Lipids pmid:3306237
Dinman BD Aluminum in the lung: the pyropowder conundrum. 1987 J Occup Med pmid:3316541
McCormack WM et al. Effect on birth weight of erythromycin treatment of pregnant women. 1987 Obstet Gynecol pmid:3543767