stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Bergquist SO et al. Erythromycin in the treatment of pertussis: a study of bacteriologic and clinical effects. 1987 Pediatr. Infect. Dis. J. pmid:2885802
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West AA et al. The relationship between glycosyltransferase production and membrane fatty acid composition of Streptococcus sanguis NCTC 7865 grown in the presence of protonmotive force inhibitors. 1987 J. Gen. Microbiol. pmid:2966234
Imai A and Gershengorn MC Measurement of lipid turnover in response to thyrotropin-releasing hormone. 1987 Meth. Enzymol. pmid:3037241
Roughan PG et al. Metabolism of exogenous long-chain fatty acids by spinach leaves. 1987 Arch. Biochem. Biophys. pmid:3426240
Habib NA et al. Stearic acid and carcinogenesis. 1987 Br. J. Cancer pmid:3689663
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Habib NA et al. Desaturation-producing factor present in the tissue, blood, and urine of cancer patients. 1987 Cancer Detect. Prev. pmid:3568009
Wang ST et al. A comparison of fatty acid composition of cholesteryl esters in subjects at various concentrations of serum lipid. 1987 Clin. Biochem. pmid:3568345
Pospísilová B and Kubes J [Stability of erythromycin stearate in coated tablets during the action of gastric juice in vitro]. 1987 Cesk Farm pmid:3581192
Worman CP et al. Saturation index of blood cell membrane fatty acids before and after IFN treatment in hairy cell leukemia. 1987 Leukemia pmid:3669764
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Bridges CD et al. Rhodopsin, vitamin A, and interstitial retinol-binding protein in the rd chicken. 1987 Invest. Ophthalmol. Vis. Sci. pmid:3557867
Hope MJ and Cullis PR Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. 1987 J. Biol. Chem. pmid:3558410
Husebye ES and Flatmark T Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. 1987 Biochim. Biophys. Acta pmid:3607074
Cavalleri A and Minoia C Lead level of whole blood and plasma in workers exposed to lead stearate. 1987 Scand J Work Environ Health pmid:3616550
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Crosby T et al. Identification of ecdysone 22-long-chain fatty acyl esters in newly laid eggs of the cattle tick Boophilus microplus. 1986 Biochem. J. pmid:3030275
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Muralidharan FN and Muralidharan VB Phytanoyl-CoA ligase activity in rat liver. 1986 Biochem. Int. pmid:3753503
Ball MD et al. Acyl coenzyme A:retinol acyltransferase activity and the vitamin A content of polar bear (Ursus maritimus) liver. 1986 Comp. Biochem. Physiol., B pmid:3757481
van den Reek MM et al. Use of published analyses of food items to determine dietary trans octadecenoic acid. 1986 J Am Diet Assoc pmid:3760430
Sugimoto Y et al. A 2H NMR study on alteration of the membrane organization of mouse B16 melanoma cells treated with 12-O-tetradecanoylphorbol-13-acetate. 1986 J. Biochem. pmid:3818567
Thompson W and Belina H Rapid accumulation of diacyl lipid in rat liver microsomes by selective acylation of 2-acyl-sn-glycero-3-phosphorylserine. 1986 Biochim. Biophys. Acta pmid:3707975
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Beaumelle BD and Vial HJ Modification of the fatty acid composition of individual phospholipids and neutral lipids after infection of the simian erythrocyte by Plasmodium knowlesi. 1986 Biochim. Biophys. Acta pmid:3719005
Pajor L et al. Microsomal desaturation of stearic acid in relation to lymphocyte activation. 1986 Arch. Biochem. Biophys. pmid:3485399
Ras GJ and Anderson R An in-vitro study of oral therapeutic doses of co-trimoxazole and erythromycin stearate on abnormal polymorphonuclear leucocyte migration. 1986 J. Antimicrob. Chemother. pmid:3486178
Peura P et al. The effect of ethanol on the release of free fatty acids from the brain in vivo; a study with push-pull cannula. 1986 Arch. Toxicol. Suppl. pmid:3468932
Chalupa W et al. Ruminal fermentation in vivo as influenced by long-chain fatty acids. 1986 J. Dairy Sci. pmid:3722545
Villa P et al. Effects of a new fluorinated macrolide (P-0501A) and other erythromycins on drug metabolizing enzymes in rat liver. 1986 J. Antibiot. pmid:3084433
Okabe H et al. Effects of anti-convulsants on fatty acid metabolism in human serum. 1986 Tohoku J. Exp. Med. pmid:3705068
Siegel I et al. Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. 1986 Fertil. Steril. pmid:2868925
Johansson ME and Nicklasson M Investigation of the film formation of magnesium stearate by applying a flow-through dissolution technique. 1986 J. Pharm. Pharmacol. pmid:2869127
Tabachnick M and Korcek L Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. 1986 Biochim. Biophys. Acta pmid:2869786