| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Seizures | D012640 | 87 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Canonico PL et al. | Arachidonate stimulates prolactin release in vitro: a role for the fatty acid and its metabolites as intracellular regulator(s) in mammotrophs. | 1985 | Endocrinology | pmid:2981065 |
| Shanson DC et al. | Erythromycin stearate, 1.5 g, for the oral prophylaxis of streptococcal bacteraemia in patients undergoing dental extraction: efficacy and tolerance. | 1985 | J. Antimicrob. Chemother. | pmid:3882657 |
| Politi LE et al. | Dexamethasone effect on free fatty acid and diacylglycerol accumulation during experimentally induced vasogenic brain edema. | 1985 | Neurochem Pathol | pmid:3831846 |
| Johansson ME | Investigations of the mixing time dependence of the lubricating properties of granular and powdered magnesium stearate. | 1985 | Acta Pharm. Suec. | pmid:3832785 |
| Goto S et al. | [Effect of magnesium stearate in preparation of eudragit RS-microcapsules containing drugs]. | 1985 | Yakugaku Zasshi | pmid:3835255 |
| Boiron F et al. | A comparison of substrate-dependent fatty acyl-CoA synthetase activities and ATP hydrolysis in membrane pellets from normal and trembler mouse sciatic nerves. | 1985 | Neurochem. Int. | pmid:20492990 |
| Rendu F et al. | Platelet membrane molecular organization: relationship with membrane bound calcium. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2983699 |
| Roughan PG | Phosphatidylglycerol and chilling sensitivity in plants. | 1985 | Plant Physiol. | pmid:16664127 |
| Roblot L et al. | Effect of lubricant level and applied compressional pressure on surface friction of tablets. | 1985 | J Pharm Sci | pmid:4020661 |
| Fujii M et al. | Fatty acid compositions of triacylglycerols and phospholipids in hen liver lipid before and after sexual maturity. | 1985 | Poult. Sci. | pmid:4022907 |
| Carranco E et al. | Carbamazepine toxicity induced by concurrent erythromycin therapy. | 1985 | Arch. Neurol. | pmid:3977647 |
| Ruwart MJ et al. | 16,16-Dimethyl PGE2 and fatty acids protect hepatocytes against CCl4-induced damage. | 1985 | In Vitro Cell. Dev. Biol. | pmid:4030626 |
| Sklan D et al. | Digestion and absorption of lipids and bile acids in sheep fed stearic acid, oleic acid, or tristearin. | 1985 | J. Dairy Sci. | pmid:4031186 |
| Bridges CD et al. | Vitamin A and interstitial retinol-binding protein in an eye with recessive retinitis pigmentosa. | 1985 | Invest. Ophthalmol. Vis. Sci. | pmid:4039711 |
| Beckurts TE et al. | Kinetics of different 123I- and 14C-labelled fatty acids in normal and diabetic rat myocardium in vivo. | 1985 | Nucl Med Commun | pmid:4047532 |
| Plachy J et al. | In vitro biopharmaceutical test for wetting rate. | 1985 | Acta Pharm Hung | pmid:4050448 |
| Griffiths G et al. | The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. | 1985 | Biochem. J. | pmid:4052051 |
| Stubbs C et al. | Determination of erythromycin in serum and urine by high-performance liquid chromatography with ultraviolet detection. | 1985 | J Pharm Sci | pmid:4078714 |
| Baker RR and Loh ZD | The subcellular distribution of free fatty acids released during post-decapitative ischemia in rat cerebral cortex. | 1985 | Can. J. Biochem. Cell Biol. | pmid:4084856 |
| Tse AG et al. | A glycophospholipid tail at the carboxyl terminus of the Thy-1 glycoprotein of neurons and thymocytes. | 1985 | Science | pmid:2865810 |
| Crutchley DJ | Hydroxyeicosatetraenoic acids and other unsaturated fatty acids inhibit endotoxin-induced thromboplastin activity in human monocytes. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2865954 |
| Johansson ME | Influence of the granulation technique and starting material properties on the lubricating effect of granular magnesium stearate. | 1985 | J. Pharm. Pharmacol. | pmid:2867134 |
| Staniforth JN | Relationship between particle packing and the physical stability of powder mixes. | 1985 | J. Pharm. Pharmacol. | pmid:2867136 |
| Schreiner A and Digranes A | Absorption of erythromycin stearate and enteric-coated erythromycin base after a single oral dose immediately before breakfast. | 1984 Sep-Oct | Infection | pmid:6511088 |
| Blackett PR et al. | Hyperlipidemia in acute lymphoblastic leukemia. | 1984 Mar-Apr | Ann. Clin. Lab. Sci. | pmid:6585175 |
| Hanna GM | Nuclear magnetic resonance spectroscopic determination of dicyclomine hydrochloride in tablet, capsule, and injection dosage forms. | 1984 Mar-Apr | J Assoc Off Anal Chem | pmid:6725188 |
| Holub BJ and Celi B | Evaluation of the fatty acid selectivity of a phosphatidylinositol-specific cytosolic phospholipase C from pig and human platelets. | 1984 Feb-Mar | Can. J. Biochem. Cell Biol. | pmid:6518412 |
| Ras GJ et al. | Chemoprophylaxis with erythromycin stearate or amoxycillin in patients with chronic bronchitis--effects on cellular and humoral immune functions. | 1984 Dec 22-29 | S. Afr. Med. J. | pmid:6515508 |
| Anderson R et al. | Studies on the effects of ingestion of a single 500 mg oral dose of erythromycin stearate on leucocyte motility and transformation and on release in vitro of prostaglandin E2 by stimulated leucocytes. | 1984 | J. Antimicrob. Chemother. | pmid:6592163 |
| Colombo I and Carli F | Comparative evaluation of structure and micromeritics properties of magnesium stearate. | 1984 | Farmaco Prat | pmid:6510514 |
| Romanowski B and Grace M | Non-gonococcal urethritis: a comparison of therapy with minicycline, tetracycline and erthromycin. | 1984 | Can Fam Physician | pmid:21278971 |
| Pediconi MF and RodrÃguez de Turco EB | Free fatty acid content and release kinetics as manifestations of cerebral lateralization in mouse brain. | 1984 | J. Neurochem. | pmid:6726237 |
| Aylsworth CF et al. | Promotion of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis by high dietary fat in the rat: possible role of intercellular communication. | 1984 | J. Natl. Cancer Inst. | pmid:6422115 |
| Kido H et al. | Inhibition of chymase activity by long chain fatty acids. | 1984 | Arch. Biochem. Biophys. | pmid:6424574 |
| Feix JB et al. | An electron-electron double-resonance study of interactions between [14N]- and [15N]stearic acid spin-label pairs: lateral diffusion and vertical fluctuations in dimyristoylphosphatidylcholine. | 1984 | Biochemistry | pmid:6329270 |
| Francis H et al. | Severe vascular spasm due to erythromycin-ergotamine interaction. | 1984 | Clin. Rheumatol. | pmid:6236021 |
| Bhakoo KK et al. | Regional studies of changes in brain fatty acids following experimental ischaemia and reperfusion in the gerbil. | 1984 | J. Neurochem. | pmid:6236282 |
| Junginger H | [The ratio of free and fixed interlamellar water as quality criteria for O/W creams]. | 1984 | Pharmazie | pmid:6504995 |
| Kennett FF et al. | Inhibition of myocardial rotenone-insensitive NADH cytochrome c reductase by amphiphilic compounds. | 1984 | Am. J. Physiol. | pmid:6507637 |
| Wirthensohn G et al. | Phospholipid metabolism in rat kidney cortical tubules. I. Effect of renal substrates. | 1984 | Biochim. Biophys. Acta | pmid:6477951 |
| Shechter Y and Henis YI | Cis-unsaturated fatty acids induce both lipogenesis and calcium binding in adipocytes. | 1984 | Biochim. Biophys. Acta | pmid:6477975 |
| Bogdanov AA et al. | Immobilization of alpha-chymotrypsin on sucrose stearate--palmitate containing liposomes. | 1984 | FEBS Lett. | pmid:6479332 |
| Junginger HE | Colloidal structures of O/W creams. | 1984 | Pharm Weekbl Sci | pmid:6483570 |
| Mogelson S and Lange LG | Nonoxidative ethanol metabolism in rabbit myocardium: purification to homogeneity of fatty acyl ethyl ester synthase. | 1984 | Biochemistry | pmid:6487591 |
| Boakes AJ et al. | Treatment of uncomplicated gonorrhoea in women with a combination of rifampicin and erythromycin. | 1984 | Br J Vener Dis | pmid:6487986 |
| Fernandes AC et al. | Enhancement of human polymorphonuclear leucocyte motility by erythromycin in vitro and in vivo. | 1984 | S. Afr. Med. J. | pmid:6463793 |
| Yoshida S and Takeshita M | Arachidoyl- and arachidonoyl-CoA elongation mechanism in swine cerebral microsomes. | 1984 | Biochim. Biophys. Acta | pmid:6466693 |
| Waldman SA et al. | Acyl composition and phospholipase activities in plasma membranes isolated from rat embryos. | 1984 | Int. J. Biochem. | pmid:6468725 |
| Slevin ML et al. | The pharmacokinetics of subcutaneous bolus cytosine arabinoside in an arachis oil plus aluminium distearate suspension. | 1984 | Invest New Drugs | pmid:6511233 |
| Vandermeerschen-Doizé F and Paquay R | Effects of continuous long-term intravenous infusion of long-chain fatty acids on feeding behaviour and blood components of adult sheep. | 1984 | Appetite | pmid:6517567 |