stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Anderson R et al. Studies on the effects of ingestion of a single 500 mg oral dose of erythromycin stearate on leucocyte motility and transformation and on release in vitro of prostaglandin E2 by stimulated leucocytes. 1984 J. Antimicrob. Chemother. pmid:6592163
Colombo I and Carli F Comparative evaluation of structure and micromeritics properties of magnesium stearate. 1984 Farmaco Prat pmid:6510514
Romanowski B and Grace M Non-gonococcal urethritis: a comparison of therapy with minicycline, tetracycline and erthromycin. 1984 Can Fam Physician pmid:21278971
Pediconi MF and Rodríguez de Turco EB Free fatty acid content and release kinetics as manifestations of cerebral lateralization in mouse brain. 1984 J. Neurochem. pmid:6726237
Aylsworth CF et al. Promotion of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis by high dietary fat in the rat: possible role of intercellular communication. 1984 J. Natl. Cancer Inst. pmid:6422115
Kido H et al. Inhibition of chymase activity by long chain fatty acids. 1984 Arch. Biochem. Biophys. pmid:6424574
Feix JB et al. An electron-electron double-resonance study of interactions between [14N]- and [15N]stearic acid spin-label pairs: lateral diffusion and vertical fluctuations in dimyristoylphosphatidylcholine. 1984 Biochemistry pmid:6329270
Bhakoo KK et al. Regional studies of changes in brain fatty acids following experimental ischaemia and reperfusion in the gerbil. 1984 J. Neurochem. pmid:6236282
Abumrad NA et al. Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. 1984 J. Biol. Chem. pmid:6746632
Junginger H [The ratio of free and fixed interlamellar water as quality criteria for O/W creams]. 1984 Pharmazie pmid:6504995
Kennett FF et al. Inhibition of myocardial rotenone-insensitive NADH cytochrome c reductase by amphiphilic compounds. 1984 Am. J. Physiol. pmid:6507637
Wirthensohn G et al. Phospholipid metabolism in rat kidney cortical tubules. I. Effect of renal substrates. 1984 Biochim. Biophys. Acta pmid:6477951
Shechter Y and Henis YI Cis-unsaturated fatty acids induce both lipogenesis and calcium binding in adipocytes. 1984 Biochim. Biophys. Acta pmid:6477975
Bogdanov AA et al. Immobilization of alpha-chymotrypsin on sucrose stearate--palmitate containing liposomes. 1984 FEBS Lett. pmid:6479332
Junginger HE Colloidal structures of O/W creams. 1984 Pharm Weekbl Sci pmid:6483570
Mogelson S and Lange LG Nonoxidative ethanol metabolism in rabbit myocardium: purification to homogeneity of fatty acyl ethyl ester synthase. 1984 Biochemistry pmid:6487591
Boakes AJ et al. Treatment of uncomplicated gonorrhoea in women with a combination of rifampicin and erythromycin. 1984 Br J Vener Dis pmid:6487986
Fernandes AC et al. Enhancement of human polymorphonuclear leucocyte motility by erythromycin in vitro and in vivo. 1984 S. Afr. Med. J. pmid:6463793
Yoshida S and Takeshita M Arachidoyl- and arachidonoyl-CoA elongation mechanism in swine cerebral microsomes. 1984 Biochim. Biophys. Acta pmid:6466693
Waldman SA et al. Acyl composition and phospholipase activities in plasma membranes isolated from rat embryos. 1984 Int. J. Biochem. pmid:6468725
Slevin ML et al. The pharmacokinetics of subcutaneous bolus cytosine arabinoside in an arachis oil plus aluminium distearate suspension. 1984 Invest New Drugs pmid:6511233
Vandermeerschen-Doizé F and Paquay R Effects of continuous long-term intravenous infusion of long-chain fatty acids on feeding behaviour and blood components of adult sheep. 1984 Appetite pmid:6517567
Hunter JM and Sommerville RG Erythromycin stearate in treating chlamydial infection of the cervix. 1984 Br J Vener Dis pmid:6518350
Farkas T Adaptation of fatty acid composition to temperature--a study on carp (Cyprinus carpio L.) liver slices. 1984 Comp. Biochem. Physiol., B pmid:6518757
Magill A and Becker AR Spectrophotometric method for quantitation of peroxides in sorbitan monooleate and monostearate. 1984 J Pharm Sci pmid:6520780
Ueda A et al. Experimental study on the pathological changes in lung tissue caused by zinc stearate dust. 1984 Ind Health pmid:6526700
Rosén C et al. Acute otitis media in older children and adults treated with phenoxymethyl penicillin or erythromycin stearate. Bacteriological and immunological aspects. 1983 Sep-Oct Acta Otolaryngol. pmid:6416018
Robson HG et al. Comparison of rosaramicin and erythromycin stearate for treatment of cervical infection with Chlamydia trachomatis. 1983 Jul-Sep Sex Transm Dis pmid:6648747
Hashisaki P et al. Erythromycin failure in the treatment of syphilis in a pregnant woman. 1983 Jan-Mar Sex Transm Dis pmid:6601848
Rosenthal MD and Whitehurst MC Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. 1983 Biochim. Biophys. Acta pmid:6615875
Hwang CC and Danti AG Percutaneous absorption of flufenamic acid in rabbits: effect of dimethyl sulfoxide and various nonionic surface-active agents. 1983 J Pharm Sci pmid:6620136
Philip J and Daly RE Test for selection of erythromycin stearate bulk drug for tablet preparation. 1983 J Pharm Sci pmid:6620167
Shih JC and Ohsawa R Differential effect of cholesterol on two types of 5-hydroxytryptamine binding sites. 1983 Neurochem. Res. pmid:6621769
van Kamp HV et al. Improvement by super disintegrants of the properties of tablets containing lactose, prepared by wet granulation. 1983 Pharm Weekbl Sci pmid:6622211
Warhurst DC et al. The blood schizontocidal action of erythromycin against Plasmodium knowlesi infections in Macaca mulatta. 1983 Ann Trop Med Parasitol pmid:6625724
Saatov TS et al. [Content, intensity of exchange, and metabolic interaction of phospholipids and glycolipids in various tissues in experimental diabetes]. 1983 Biokhimiia pmid:6671113
Kushi Y et al. Comparative study of acidic glycosphingolipids by field desorption and secondary ion mass spectrometry. 1983 J. Biochem. pmid:6671968
Green B et al. Qualitative and quantitative changes in milk fat during lactation in the tammar wallaby (Macropus eugenii). 1983 Aust. J. Biol. Sci. pmid:6675645
Tulenko TN and Rabinowitz JL Metabolism of C14 mevalonate by adult and fetal arteries. 1983 Artery pmid:6677248
AkbuÄŸa J et al. Studies on flufenamic acid capsules and tablets. 1983 Pharmazie pmid:6634915
Pethick DW et al. The metabolism of circulating non-esterified fatty acids by the whole animal, hind-limb muscle and uterus of pregnant ewes. 1983 Br. J. Nutr. pmid:6821682
Shanson DC et al. High dose oral erythromycin for preventing endocarditis. 1983 Lancet pmid:6130318
de Haan P and Kalsbeek GL Humoral immune response to some benzylpenicillin preparations. 1983 Allergy pmid:6412583
Anderton P et al. Measles-virus-persistent infection in BGM cells. Modification of the incorporation of [3H]arachidonic acid and [14C]stearic acid into lipids. 1983 Biochem. J. pmid:6414459
Süss W [Production of delayed-release formulations based on hydrophilic matrix forms using polyvinyl alcohol]. 1983 Pharmazie pmid:6415679
Bascoul J et al. Preparation of autoxidized cholesterol mixtures from [4-14C] cholesterol and cholesteryl fatty acid esters. 1983 J. Steroid Biochem. pmid:6423895
Kemp P and Lander DJ The hydrogenation of gamma-linolenic acid by pure cultures of two rumen bacteria. 1983 Biochem. J. pmid:6318740
Walsh CE et al. Mechanism of arachidonic acid release in human polymorphonuclear leukocytes. 1983 Biochim. Biophys. Acta pmid:6402027
Bleeker J Tolerance and efficacy of erythromycin stearate tablets versus enteric-coated erythromycin base capsules in the treatment of patients with acne vulgaris. 1983 J. Int. Med. Res. pmid:6219902
Neufeld EJ et al. High affinity esterification of eicosanoid precursor fatty acids by platelets. 1983 J. Clin. Invest. pmid:6308046