stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Rosenthal MD and Whitehurst MC Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. 1983 Biochim. Biophys. Acta pmid:6615875
Hwang CC and Danti AG Percutaneous absorption of flufenamic acid in rabbits: effect of dimethyl sulfoxide and various nonionic surface-active agents. 1983 J Pharm Sci pmid:6620136
Hikal AH Dissolution of meprobamate from various tablet formulations. 1983 Pharmazie pmid:6669616
Kohn MC and Garfinkel D Computer simulation of metabolism in palmitate-perfused rat heart. I. Palmitate oxidation. 1983 Ann Biomed Eng pmid:6592996
Duncan MO et al. Treatment of chancroid with erythromycin. A clinical and microbiological appraisal. 1983 Br J Vener Dis pmid:6603249
Upreti GC et al. Membrane lipids of hepatic tissue. I. Neutral lipids from subcellular fractions of liver and hepatoma 7288CTC. 1983 J. Natl. Cancer Inst. pmid:6572743
Erman A et al. Phospholipase A2 inhibitors. Differential inhibition of fatty acid acylation into kidney lipids by mepacrine and p-bromophenacyl bromide. 1983 Biochem. Pharmacol. pmid:6870935
Flood MT et al. Vitamin A utilization in human retinal pigment epithelial cells in vitro. 1983 Invest. Ophthalmol. Vis. Sci. pmid:6885309
Chien JL and Hogan EL Novel pentahexosyl ganglioside of the globo series purified from chicken muscle. 1983 J. Biol. Chem. pmid:6885798
Edwards EK and Edwards EK Allergic reaction to triethanolamine stearate in a sunscreen. 1983 Cutis pmid:6831931
Chapkin RS et al. Characterization of the individual phospholipids and their fatty acids in serum and high-density lipoprotein of the renal patient on long-term maintenance hemodialysis. 1983 J. Lab. Clin. Med. pmid:6833842
Hillmar I et al. Influence of fatty acids on microsomal diacylglycerol acyltransferase activity in primary cultures of hepatocytes. 1983 Hoppe-Seyler's Z. Physiol. Chem. pmid:6840704
Warrell DA et al. Pathophysiology and immunology of the Jarisch-Herxheimer-like reaction in louse-borne relapsing fever: comparison of tetracycline and slow-release penicillin. 1983 J. Infect. Dis. pmid:6842024
Zeisel SH et al. Formation of methylamines from ingested choline and lecithin. 1983 J. Pharmacol. Exp. Ther. pmid:6842395
Foot M et al. Some properties, including the substrate in vivo, of the delta 9-desaturase in Micrococcus cryophilus. 1983 Biochem. J. pmid:6847622
Quinn PA et al. Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas. 1983 Am. J. Obstet. Gynecol. pmid:6849358
Streichman S et al. Unique profile for erythrocyte membrane acetylcholinesterase in hereditary spherocytosis. 1983 Biochim. Biophys. Acta pmid:6849970
Sobel JD et al. Legionella bozemanii. Still another cause of pneumonia. 1983 JAMA pmid:6854903
Stults BM et al. Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease. 1983 South. Med. J. pmid:6857302
Slomiany A et al. Isolation of fatty acids covalently bound to the gastric mucus glycoprotein of normal and cystic fibrosis patients. 1983 Biochem. Biophys. Res. Commun. pmid:6860340
Slomiany A et al. Covalently linked fatty acids in gastric mucus glycoprotein of cystic fibrosis patients. 1983 J. Biol. Chem. pmid:6863300
Khan KA et al. The effect of mixing time of magnesium stearate on the tableting properties of dried microcrystalline cellulose. 1983 Pharm Acta Helv pmid:6867042
Shanson DC et al. High dose oral erythromycin for preventing endocarditis. 1983 Lancet pmid:6130318
Yoshida S et al. Brain free fatty acids, edema, and mortality in gerbils subjected to transient, bilateral ischemia, and effect of barbiturate anesthesia. 1983 J. Neurochem. pmid:6403669
Swendsen CL et al. 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine: a novel source of arachidonic acid in neutrophils stimulated by the calcium ionophore A23187. 1983 Biochem. Biophys. Res. Commun. pmid:6407484
Inman WH and Rawson NS Erythromycin estolate and jaundice. 1983 Br Med J (Clin Res Ed) pmid:6407653
Carli F and Colombo I Influence of porosity on the contact angle of non-wet solids. 1983 J. Pharm. Pharmacol. pmid:6135790
Gabriel SM and Simpkins JW Effects of a sustained-release naloxone pellet on luteinizing hormone secretion in female rats. 1983 Neuroendocrinology pmid:6139759
Agrawal HC et al. In vivo incorporation of [3H]palmitic acid into PO protein, the major intrinsic protein of rat sciatic nerve myelin. 1983 J. Biol. Chem. pmid:6189827
Neufeld EJ et al. High affinity esterification of eicosanoid precursor fatty acids by platelets. 1983 J. Clin. Invest. pmid:6308046
Oriel JD et al. Treatment of gonococcal urethritis in men with a rifampicin-erythromycin combination. 1982 Oct-Dec Sex Transm Dis pmid:6821502
della Ventura A and della Ventura D [Clinical experiments with erythromycin stearate in surgery of the oral cavity]. 1982 May-Jun Odontostomatol Implantoprotesi pmid:6984149
May DC et al. The effects of erythromycin on theophylline elimination in normal males. 1982 Feb-Mar J Clin Pharmacol pmid:7068935
Wei TC Quantitative determination of chemical composition of gallstones by infrared absorption spectrophotometry. 1982 Taiwan Yi Xue Hui Za Zhi pmid:6954245
Slomiany BL et al. Lipid composition of the matrix of human submandibular salivary gland stones. 1982 Arch. Oral Biol. pmid:6958224
Tinsley IJ et al. Tissue fatty acid changes and tumor incidence in C3H mice ingesting cottonseed oil. 1982 Lipids pmid:6896358
Goto M et al. Evidence for a correlation between swimming velocity and membrane fluidity of Tetrahymena cells. 1982 Biochim. Biophys. Acta pmid:6818990
Moore KH et al. beta-Hydroxy fatty acid production by ischemic rabbit heart. 1982 J. Clin. Invest. pmid:6799549
Hong SL and Deykin D Activation of phospholipases A2 and C in pig aortic endothelial cells synthesizing prostacyclin. 1982 J. Biol. Chem. pmid:6806265
Bridges CD et al. Vitamin A in human eyes: amount, distribution, and composition. 1982 Invest. Ophthalmol. Vis. Sci. pmid:7076416
Lehmann J and McGill M Biochemical and ultrastructural alterations in platelets, reticulocytes, and lymphocytes from rats fed vitamin E-deficient diets. 1982 J. Lipid Res. pmid:7077144
Josefsson K et al. Dose-related pharmacokinetics after oral administration of a new formulation of erythromycin base. 1982 Br J Clin Pharmacol pmid:7082537
NadtochiÄ­ VV and BrodskiÄ­ RA [Absorption study of 3H-stearic acid in the rat small intestine using electron microscopic autoradiography]. 1982 Tsitologiia pmid:7135486
Chen SC et al. Calorimetric evidence for phase transitions in spin-label lipid bilayers. 1982 Biochemistry pmid:7138849
Mroso PV et al. Solid-state stability of aspirin in the presence of excipients: kinetic interpretation, modeling, and prediction. 1982 J Pharm Sci pmid:7143203
Katz AM and Messineo FC Fatty acid effects on membranes: possible role in the pathogenesis of ischemic myocardial damage. 1982 J. Mol. Cell. Cardiol. pmid:7143451
Lerk CF et al. Interaction of tablet disintegrants and magnesium stearate during mixing. II. Effect on dissolution rate. 1982 Pharm Acta Helv pmid:7146030
Warner T and Zar JH Fatty acid composition of brown fat and brain fat of the little brown bat, Myotis lucifugus, during hibernation. 1982 Comp. Biochem. Physiol., B pmid:7151405
Iliopoulou A et al. Should erythromycin dose be altered in haemodialysis patients? 1982 Eur. J. Clin. Pharmacol. pmid:7151848
Bazan NG et al. High content of 22:6 (docosahexaenoate) and active [2-3H]glycerol metabolism of phosphatidic acid from photoreceptor membranes. 1982 Biochim. Biophys. Acta pmid:6215065