| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Seizures | D012640 | 87 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Stubbs C et al. | Determination of erythromycin in serum and urine by high-performance liquid chromatography with ultraviolet detection. | 1985 | J Pharm Sci | pmid:4078714 |
| Baker RR and Loh ZD | The subcellular distribution of free fatty acids released during post-decapitative ischemia in rat cerebral cortex. | 1985 | Can. J. Biochem. Cell Biol. | pmid:4084856 |
| Galpin JR and Allen JC | The influence of micelle formation on lipoxygenase kinetics. | 1977 | Biochim. Biophys. Acta | pmid:409436 |
| Nossel HL et al. | Inhibition of collagen-induced platelet aggregation by normal plasma. | 1971 | J. Clin. Invest. | pmid:4107268 |
| Butcher AE and Jones TM | Some physical characteristics of magnesium stearate. | 1972 | J. Pharm. Pharmacol. | pmid:4144914 |
| Welling PG et al. | Plasma levels following single and repeated doses of erythromycin estolate and erythromycin stearate. | 1979 | J Pharm Sci | pmid:423080 |
| Lerk CF et al. | Effect of microcrystalline cellulose on liquid penetration in and disintegration of directly compressed tablets. | 1979 | J Pharm Sci | pmid:423092 |
| Kaur R and Grant DJ | Solid dispersions of drugs in polyoxyethylene 40 stearate: dissolution rates and physico-chemical interactions [proceedings]. | 1979 | J. Pharm. Pharmacol. | pmid:42723 |
| Eccleston GM | The structure and stability of O/W emulsions stabilised by polyethylene glycol 1000 monostearate/fatty alcohols [proceedings]. | 1979 | J. Pharm. Pharmacol. | pmid:42725 |
| Moody G et al. | Lubricity measurements of magnesium stearate [proceedings]. | 1979 | J. Pharm. Pharmacol. | pmid:42749 |
| Doran TA et al. | Amniotic fluid lecithin/sphingomyelin ratio, palmitic acid, palmitic acid/stearic acid ratio, total cortisol, creatinine, and percentage of lipid-positive cells in assessment of fetal maturity and fetal pulmonary maturity: a comparison. | 1979 | Am. J. Obstet. Gynecol. | pmid:433991 |
| Nielsen GD et al. | [Aspiration of talcum or powder containing zinc stearate by children]. | 1979 | Ugeskr. Laeg. | pmid:442270 |
| Kasuya M et al. | Toxic effect of cadmium stearate on rat cerebellum in culture. | 1974 | Bull Environ Contam Toxicol | pmid:4474041 |
| Bond JM et al. | The second international reference preparation of procaine benzylpenicillin in oil with aluminium monostearate. | 1973 | Bull. World Health Organ. | pmid:4541152 |
| Ryan DC et al. | Estolate and stearate forms of erythromycin in the treatment of acute beta haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4568626 |
| Bhatia RP and Lordi NG | Conductivity and hardness changes in aged compacts. | 1979 | J Pharm Sci | pmid:458612 |
| Antimicrobial efficacy of erythromycin stearate. A report from the general Practitioner Research Group. | 1974 | Practitioner | pmid:4591200 | |
| Holub BJ and Piekarski J | The formation of phosphatidylinositol by acylation of 2-acyl-sn-glycero-3-phosphorylinositol in rat liver microsomes. | 1979 | Lipids | pmid:459717 |
| Zackler J et al. | A mass screening program for the detection of gonorrhea. | 1972 | Am. J. Obstet. Gynecol. | pmid:4623083 |
| Wahle KW and Garton GA | Desaturation of stearate by sheep tissue microsomal preparations. | 1972 | Biochem. J. | pmid:4643297 |
| Kabara JJ et al. | Fatty acids and derivatives as antimicrobial agents. | 1972 | Antimicrob. Agents Chemother. | pmid:4670656 |
| Berend N et al. | Plasma and saliva concentrations for a new formulation of erythromycin stearate. | 1979 | Curr Med Res Opin | pmid:467089 |
| Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. | 1972 | Yakugaku Zasshi | pmid:4675495 |
| McLeay A and Cooke P | Estolate and stearate forms of erythromycin in beta-haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4694278 |
| Arya OP and Bosa CB | In search of an ideal single-session penicillin schedule for the treatment of gonorrhoea in Uganda. | 1973 | Br J Vener Dis | pmid:4748409 |
| Riordan JR et al. | Plasma membrane lipids of human diploid fibroblasts from normal individuals and patients with cystic fibrosis. | 1979 | Biochim. Biophys. Acta | pmid:476136 |
| Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. | 1973 | Yakugaku Zasshi | pmid:4797567 |
| Caldwell HC | Dissolution of lithium and magnesium from lithium carbonate capsules containing magnesium stearate. | 1974 | J Pharm Sci | pmid:4830001 |
| Beleslin DB et al. | Hyperthermic effect of palmitate sodium, stearate sodium and oleate sodium injected into the cerebral ventricles of conscious cats. | 1974 | Neuropharmacology | pmid:4840846 |
| McLeay AC and Beveridge J | Clinical trial of erythromycin stearate suspension. | 1971 | Med. J. Aust. | pmid:4929585 |
| Carlisle HN and Saslaw S | Therapy of staphylococcal infections in monkeys. VI. Comparison of clindamycin, erythromycin, and methicillin. | 1971 | Appl Microbiol | pmid:4994902 |
| Malmborg AS | Effect of food on absorption of erythromycin. A study of two derivatives, the stearate and the base. | 1979 | J. Antimicrob. Chemother. | pmid:500517 |
| Wosilait WD and Ryan MP | The effects of oleic acid, tolbutamide, and oxyphenbutazone on the binding of warfarin by human serum albumin. | 1979 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:504792 |
| Conte U et al. | The effect of magnesium stearate and polytetrafluoroethylene as lubricants in direct compression of acetylsalicylic acid. | 1972 | Farmaco Prat | pmid:5049531 |
| Lesslauer W and Blasie JK | Direct determination of the structure of barium stearate multilayers by x-ray diffraction. | 1972 | Biophys. J. | pmid:5057749 |
| Price CJ and Rowe CE | Stimulation of the production of unesterified fatty acids in nerve endings of guinea-pig brain in vitro by noradrenaline and 5-hydroxytryptamine. | 1972 | Biochem. J. | pmid:5075269 |
| Patil GS et al. | Effect of ionization and cation selectivity on the expansion of stearic acid monolayers. | 1972 | J. Lipid Res. | pmid:5075503 |
| Rutland J et al. | The influence of food on the bioavailability of new formulations of erythromycin stearate and base. | 1979 | Br J Clin Pharmacol | pmid:508509 |
| Schmidt P et al. | [Acute inhalation toxicity of cadmium stearate]. | 1971 | Z Gesamte Hyg | pmid:5123074 |
| Caille MP et al. | [Acute forms of lead poisoning by lead stearate]. | 1971 | Arch Mal Prof | pmid:5123552 |
| Pinzauti S and La Porta E | Assay of a cetylpyridinium-dequalinium chlorides combination in compressed lozenges: uptake of quaternary ammonium salts by magnesium stearate. | 1979 Sep-Oct | J Pharm Belg | pmid:512830 |
| Yakatan GJ et al. | Single-dose fasting bioequivalence assessment of erythromycin stearate tablets in man. | 1979 | J Pharmacokinet Biopharm | pmid:512842 |
| Bell SM | A comparison of absorption after oral administration of erythromycin estolate and erythromycin stearate. | 1971 | Med. J. Aust. | pmid:5134726 |
| Molloy PL and Eisenstadt JM | Erythromycin resistance in mouse L cells. | 1979 | Somatic Cell Genet. | pmid:531731 |
| Smith DD | Clinical trial of erythromycin stearate suspension. | 1971 | Med. J. Aust. | pmid:5577264 |
| Boggiano BG and Gleeson M | Gastric acid inactivation of erythromycin stearate in solid dosage forms. | 1976 | J Pharm Sci | pmid:5588 |
| Burns CP et al. | Fatty acid utilization by L1210 murine leukemia cells. | 1977 | Cancer Res. | pmid:558821 |
| Yang YT et al. | Dietary lipid metabolism in lactating dairy cows. | 1978 | J. Dairy Sci. | pmid:568635 |
| Nicoletti R et al. | [Palmitic acid-stearic acid ratio with reference to the fatty tissue properties in the human species]. | 1979 May-Jun | Arch Kriminol | pmid:573992 |
| Bolton P and Harwood JL | Fatty acid biosynthesis by a particulate preparation from germinating pea. | 1977 | Biochem. J. | pmid:579600 |