stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Rosén C et al. Acute otitis media in older children and adults treated with penicillin or erythromycin. 1984 Acta Otolaryngol Suppl pmid:6437133
Dixon JF and Hokin LE Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase. 1984 J. Biol. Chem. pmid:6438097
Forsberg NE et al. Roles of acetate and its interactions with glucose and lactate in cow mammary tissue. 1984 J. Dairy Sci. pmid:6438200
Desudchit P et al. Rifampicin-erythromycin combination for the treatment of gonococcal urethritis in men. 1984 Southeast Asian J. Trop. Med. Public Health pmid:6441265
Bleeker J et al. Effect of systemic erythromycin stearate on the inflammatory lesions and skin surface fatty acids in acne vulgaris. 1981 Dermatologica pmid:6454598
Fernandes AC et al. Enhancement of human polymorphonuclear leucocyte motility by erythromycin in vitro and in vivo. 1984 S. Afr. Med. J. pmid:6463793
Yoshida S and Takeshita M Arachidoyl- and arachidonoyl-CoA elongation mechanism in swine cerebral microsomes. 1984 Biochim. Biophys. Acta pmid:6466693
Waldman SA et al. Acyl composition and phospholipase activities in plasma membranes isolated from rat embryos. 1984 Int. J. Biochem. pmid:6468725
Wirthensohn G et al. Phospholipid metabolism in rat kidney cortical tubules. I. Effect of renal substrates. 1984 Biochim. Biophys. Acta pmid:6477951
Shechter Y and Henis YI Cis-unsaturated fatty acids induce both lipogenesis and calcium binding in adipocytes. 1984 Biochim. Biophys. Acta pmid:6477975
Bogdanov AA et al. Immobilization of alpha-chymotrypsin on sucrose stearate--palmitate containing liposomes. 1984 FEBS Lett. pmid:6479332
Junginger HE Colloidal structures of O/W creams. 1984 Pharm Weekbl Sci pmid:6483570
Mogelson S and Lange LG Nonoxidative ethanol metabolism in rabbit myocardium: purification to homogeneity of fatty acyl ethyl ester synthase. 1984 Biochemistry pmid:6487591
Boakes AJ et al. Treatment of uncomplicated gonorrhoea in women with a combination of rifampicin and erythromycin. 1984 Br J Vener Dis pmid:6487986
Fenyvest E et al. Cyclodextrin polymer, a new tablet disintegrating agent. 1984 Pharmazie pmid:6494226
Junginger H [The ratio of free and fixed interlamellar water as quality criteria for O/W creams]. 1984 Pharmazie pmid:6504995
Kennett FF et al. Inhibition of myocardial rotenone-insensitive NADH cytochrome c reductase by amphiphilic compounds. 1984 Am. J. Physiol. pmid:6507637
Colombo I and Carli F Comparative evaluation of structure and micromeritics properties of magnesium stearate. 1984 Farmaco Prat pmid:6510514
Schreiner A and Digranes A Absorption of erythromycin stearate and enteric-coated erythromycin base after a single oral dose immediately before breakfast. 1984 Sep-Oct Infection pmid:6511088
Slevin ML et al. The pharmacokinetics of subcutaneous bolus cytosine arabinoside in an arachis oil plus aluminium distearate suspension. 1984 Invest New Drugs pmid:6511233
Ras GJ et al. Chemoprophylaxis with erythromycin stearate or amoxycillin in patients with chronic bronchitis--effects on cellular and humoral immune functions. 1984 Dec 22-29 S. Afr. Med. J. pmid:6515508
Vandermeerschen-Doizé F and Paquay R Effects of continuous long-term intravenous infusion of long-chain fatty acids on feeding behaviour and blood components of adult sheep. 1984 Appetite pmid:6517567
Hunter JM and Sommerville RG Erythromycin stearate in treating chlamydial infection of the cervix. 1984 Br J Vener Dis pmid:6518350
Holub BJ and Celi B Evaluation of the fatty acid selectivity of a phosphatidylinositol-specific cytosolic phospholipase C from pig and human platelets. 1984 Feb-Mar Can. J. Biochem. Cell Biol. pmid:6518412
Farkas T Adaptation of fatty acid composition to temperature--a study on carp (Cyprinus carpio L.) liver slices. 1984 Comp. Biochem. Physiol., B pmid:6518757
Magill A and Becker AR Spectrophotometric method for quantitation of peroxides in sorbitan monooleate and monostearate. 1984 J Pharm Sci pmid:6520780
Ueda A et al. Experimental study on the pathological changes in lung tissue caused by zinc stearate dust. 1984 Ind Health pmid:6526700
Bridges CD et al. Visual cycle in the mammalian eye. Retinoid-binding proteins and the distribution of 11-cis retinoids. 1984 Vision Res. pmid:6543481
Upreti GC et al. Membrane lipids of hepatic tissue. I. Neutral lipids from subcellular fractions of liver and hepatoma 7288CTC. 1983 J. Natl. Cancer Inst. pmid:6572743
Blackett PR et al. Hyperlipidemia in acute lymphoblastic leukemia. 1984 Mar-Apr Ann. Clin. Lab. Sci. pmid:6585175
Anderson R et al. Studies on the effects of ingestion of a single 500 mg oral dose of erythromycin stearate on leucocyte motility and transformation and on release in vitro of prostaglandin E2 by stimulated leucocytes. 1984 J. Antimicrob. Chemother. pmid:6592163
Kohn MC and Garfinkel D Computer simulation of metabolism in palmitate-perfused rat heart. I. Palmitate oxidation. 1983 Ann Biomed Eng pmid:6592996
Hashisaki P et al. Erythromycin failure in the treatment of syphilis in a pregnant woman. 1983 Jan-Mar Sex Transm Dis pmid:6601848
Duncan MO et al. Treatment of chancroid with erythromycin. A clinical and microbiological appraisal. 1983 Br J Vener Dis pmid:6603249
Welling PG et al. Bioavailability of erythromycin stearate: influence of food and fluid volume. 1978 J Pharm Sci pmid:660450
Abdulrazik M et al. Formulation for slow release of oral radiation-protection drugs. 1984 Int J Nucl Med Biol pmid:6610665
Rosenthal MD and Whitehurst MC Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. 1983 Biochim. Biophys. Acta pmid:6615875
Hwang CC and Danti AG Percutaneous absorption of flufenamic acid in rabbits: effect of dimethyl sulfoxide and various nonionic surface-active agents. 1983 J Pharm Sci pmid:6620136
Philip J and Daly RE Test for selection of erythromycin stearate bulk drug for tablet preparation. 1983 J Pharm Sci pmid:6620167
Shih JC and Ohsawa R Differential effect of cholesterol on two types of 5-hydroxytryptamine binding sites. 1983 Neurochem. Res. pmid:6621769
van Kamp HV et al. Improvement by super disintegrants of the properties of tablets containing lactose, prepared by wet granulation. 1983 Pharm Weekbl Sci pmid:6622211
Warhurst DC et al. The blood schizontocidal action of erythromycin against Plasmodium knowlesi infections in Macaca mulatta. 1983 Ann Trop Med Parasitol pmid:6625724
AkbuÄŸa J et al. Studies on flufenamic acid capsules and tablets. 1983 Pharmazie pmid:6634915
NadtochiÄ­ VV and BrodskiÄ­ RA [Absorption routes of stearic acid and leucine in the small intestine of the rat after gamma irradiation]. 1983 Arkh Anat Gistol Embriol pmid:6639383
Hundrieser KE et al. Distribution of trans-octadecenoic acid in the major glycerolipids of human milk. 1983 J. Pediatr. Gastroenterol. Nutr. pmid:6644446
Robson HG et al. Comparison of rosaramicin and erythromycin stearate for treatment of cervical infection with Chlamydia trachomatis. 1983 Jul-Sep Sex Transm Dis pmid:6648747
Abramov LA et al. Acute respiratory distress caused by erythromycin hypersensitivity. 1978 Arch. Intern. Med. pmid:666483
Hikal AH Dissolution of meprobamate from various tablet formulations. 1983 Pharmazie pmid:6669616
Saatov TS et al. [Content, intensity of exchange, and metabolic interaction of phospholipids and glycolipids in various tissues in experimental diabetes]. 1983 Biokhimiia pmid:6671113
Kushi Y et al. Comparative study of acidic glycosphingolipids by field desorption and secondary ion mass spectrometry. 1983 J. Biochem. pmid:6671968