stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Graham KC et al. Simple thin-layer chromatographic identification method for erythromycin stearate. 1976 J. Chromatogr. pmid:977688
Matsuda Y et al. Comparative evaluation of tablet lubricants: effect of application method on tablet hardness and ejectability after compression. 1976 J Pharm Sci pmid:978434
Todorow S and Elies W [Oily contrast medium in liquor space following myelography. A clinical-radiological study on extent, velocity and ways of elimination of monoiodine stearate]. 1976 Neurochirurgia (Stuttg) pmid:185538
Marai L et al. Identification of isomeric doxyl stearic acids by gas-liquid chromatography and mass spectrometry. 1976 Chem. Phys. Lipids pmid:186203
Phadke RS Sedimentation test for procaine benzylpenicillin in oil with aluminium monostearate. III. Substitution of the sedimentation rate for the blood-level duration test of WHO in rabbits. 1975 Aug-Nov Hindustan Antibiot Bull pmid:1236093
McGee R and Spector AA Fatty acid biosynthesis in Erlich cells. The mechanism of short term control by exogenous free fatty acids. 1975 J. Biol. Chem. pmid:237919
Choulis NH and Papadopoulos H Factors effecting drug release from inert matrices. Part 1: effects of surfactants on the release of quinine sulfate. 1975 Pharmazie pmid:239411
Kalm O et al. Erythromycin stearate in acute maxillary sinusitis. 1975 Scand. J. Infect. Dis. pmid:241119
Bieri VG and Wallach DF Variations of lipid-protein interactions in erythrocyte ghosts as a function of temperature and pH in physiological and non-physiological ranges. A study using a paramagnetic quenching of protein fluorescence by nitroxide lipid analogues. 1975 Biochim. Biophys. Acta pmid:241415
Seng PN and Debuch H [Studies on the stearic acid dehydrogenase in the liver and brain of rats of various ages (author's transl)]. 1975 Hoppe-Seyler's Z. Physiol. Chem. pmid:241688
Topping DL and Targ ME Time-course of changes in blood glucose and ketone bodies, plasma lipids and liver fatty acid composition in streptozotocin-diabetic male rats. 1975 Horm. Res. pmid:130333
Comai K et al. Analyses of renal medullary lipid droplets from normal, hydronephrotic, and indomethacin treated rabbits. 1975 Lipids pmid:1177669
Thompson GE and Darling KF The hepatic uptake of individual free fatty acids in sheep during noradrenaline infusion. 1975 Res. Vet. Sci. pmid:1144925
York P Application of powder failure testing equipment in assessing effect on glidants on flowability of cohesive pharmaceutical powders. 1975 J Pharm Sci pmid:1151687
Weaire PJ and Kekwick RG The fractionation of the fatty acid synthetase activities of avocado mesocarp plastids. 1975 Biochem. J. pmid:1156381
Janicki RS et al. Comparison of erythromycin ethyl succinate, stearate and estolate treatments of group A streptococcal infections of the upper respiratory tract. 1975 Clin Pediatr (Phila) pmid:1104241
Männistö P et al. Absorption of erythromycin. A cross-over study in healthy volunteers. 1975 Arzneimittelforschung pmid:1106445
Anderson RR et al. Composition of cottontail rabbit milk from stomachs of young and directly from gland. 1975 J. Dairy Sci. pmid:1184805
Gaginella TS et al. Actions of ricinoleic acid and structurally related fatty acids on the gastrointestinal tract. II. Effects on water and electrolyte absorption in vitro. 1975 J. Pharmacol. Exp. Ther. pmid:1185605
Smith RW and Walsh A Composition of liver lipids of the rat during pregnancy and lactation. 1975 Lipids pmid:1186452
Schmidt P et al. [Animal experiments on barium stearate toxicity]. 1975 Z Gesamte Hyg pmid:1189478
Sato M et al. [Clinical studies on OE-7 chiefly in the treatment of acute respiratory infections (author's transl)]. 1975 Jpn J Antibiot pmid:1195513
Harwood JL and James AT Metabolism of trans-3-hexadecenoic acid in broad bean. 1975 Eur. J. Biochem. pmid:1126340
Kuksis A et al. Distribution of newly formed fatty acids among glycerolipids of isolated perfused rat liver. 1975 Can. J. Biochem. pmid:1139394
Kuksis A et al. Distribution of newly formed palmitate and stearate among molecular species of choline and ethanolamine phosphatides. 1975 Can. J. Biochem. pmid:1139395
Parkes JG and Thompson W Phosphatidylethanolamine in liver mitochondria and endoplasmic reticulum: molecular species distribution and turnover. 1975 Can. J. Biochem. pmid:1139407
Tola S Occupational lead exposure in Finland. IV. The polyvinyl chloride plastic industry. 1975 Scand J Work Environ Health pmid:1228897
Kopp F et al. Instability of Langmuir-Blodgett layers of barium stearate, cadmium arachidate and tripalmitin, studied by means of electron microscopy and infrared spectroscopy. 1975 Biophys. Struct. Mech. pmid:1234025
Gray AP and Guardina WJ Long-acting narcotic antagonist complexes. 1975 Natl Inst Drug Abuse Res Monogr Ser pmid:1234981
Ercoli N [Clinical and experimental study on an anti-inflammatory preparation of topical use. The 10-undecentil-l-ll pseudothiourea (AHR-1911)]. 1975 Med Cutan Ibero Lat Am pmid:1241792
Thies C Development of injectable microcapsules for use in the treatment of narcotic addiction. 1975 Natl Inst Drug Abuse Res Monogr Ser pmid:1241971
Aveldano MI and Bazán NG Rapid production of diacylglycerols enriched in arachidonate and stearate during early brain ischemia. 1975 J. Neurochem. pmid:1206411
Pollet S et al. [Substrates and products of fatty acid elongation in mouse brain microsomes]. 1975 Biochimie pmid:1222143
Wood R Sterospecific analysis of hepatoma, host liver, and normal rat liver triglycerides from animals on chow and fat free diets. 1975 Lipids pmid:167260
Iot T et al. Synthesis of a new phosphatidylserine spin-label and calcium-induced lateral phase separation in phosphatidylserine-phosphatidylcholine membranes. 1975 Biochemistry pmid:167814
Thompson W and MacDonald G Isolation and characterization of cytidine diphosphate diglyceride from beef liver. 1975 J. Biol. Chem. pmid:169258
Morrisett JD et al. Multiple thermotropic phase transitions in Escherichia coli membranes and membrane lipids. A comparison of results obtained by nitroxyl stearate paramagnetic resonance, pyrene excimer fluorescence, and enzyme activity measurements. 1975 J. Biol. Chem. pmid:169264
Asker AF et al. Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 5: Effects of lubricants and flow conditions. 1975 Pharmazie pmid:169527
Antimicrobial efficacy of erythromycin stearate. A report from the general Practitioner Research Group. 1974 Practitioner pmid:4591200
Caldwell HC Dissolution of lithium and magnesium from lithium carbonate capsules containing magnesium stearate. 1974 J Pharm Sci pmid:4830001
Beleslin DB et al. Hyperthermic effect of palmitate sodium, stearate sodium and oleate sodium injected into the cerebral ventricles of conscious cats. 1974 Neuropharmacology pmid:4840846
Kasuya M et al. Toxic effect of cadmium stearate on rat cerebellum in culture. 1974 Bull Environ Contam Toxicol pmid:4474041
Ryan DC et al. Estolate and stearate forms of erythromycin in the treatment of acute beta haemolytic streptococcal pharyngitis. 1973 Med. J. Aust. pmid:4568626
Bond JM et al. The second international reference preparation of procaine benzylpenicillin in oil with aluminium monostearate. 1973 Bull. World Health Organ. pmid:4541152
Arya OP and Bosa CB In search of an ideal single-session penicillin schedule for the treatment of gonorrhoea in Uganda. 1973 Br J Vener Dis pmid:4748409
McLeay A and Cooke P Estolate and stearate forms of erythromycin in beta-haemolytic streptococcal pharyngitis. 1973 Med. J. Aust. pmid:4694278
Norwitz G and Gordon H Determination of lithium stearate in sebacate-based lubricants by atomic absorption. 1973 Talanta pmid:18961363
Miyake Y et al. [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. 1973 Yakugaku Zasshi pmid:4797567
Conte U et al. The effect of magnesium stearate and polytetrafluoroethylene as lubricants in direct compression of acetylsalicylic acid. 1972 Farmaco Prat pmid:5049531
Butcher AE and Jones TM Some physical characteristics of magnesium stearate. 1972 J. Pharm. Pharmacol. pmid:4144914