stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Zackler J et al. A mass screening program for the detection of gonorrhea. 1972 Am. J. Obstet. Gynecol. pmid:4623083
Wahle KW and Garton GA Desaturation of stearate by sheep tissue microsomal preparations. 1972 Biochem. J. pmid:4643297
Lesslauer W and Blasie JK Direct determination of the structure of barium stearate multilayers by x-ray diffraction. 1972 Biophys. J. pmid:5057749
Price CJ and Rowe CE Stimulation of the production of unesterified fatty acids in nerve endings of guinea-pig brain in vitro by noradrenaline and 5-hydroxytryptamine. 1972 Biochem. J. pmid:5075269
Patil GS et al. Effect of ionization and cation selectivity on the expansion of stearic acid monolayers. 1972 J. Lipid Res. pmid:5075503
Kannangara CG and Stumpf PK Fat Metabolism in Higher Plants: XLVII. The Effect of Nitrite and Other Anions on the Formation of Unsaturated Fatty Acids by Isolated Chloroplasts. 1972 Plant Physiol. pmid:16657990
Miyake Y et al. [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. 1972 Yakugaku Zasshi pmid:4675495
Kabara JJ et al. Fatty acids and derivatives as antimicrobial agents. 1972 Antimicrob. Agents Chemother. pmid:4670656
McLeay AC and Beveridge J Clinical trial of erythromycin stearate suspension. 1971 Med. J. Aust. pmid:4929585
Schmidt P et al. [Acute inhalation toxicity of cadmium stearate]. 1971 Z Gesamte Hyg pmid:5123074
Caille MP et al. [Acute forms of lead poisoning by lead stearate]. 1971 Arch Mal Prof pmid:5123552
Bell SM A comparison of absorption after oral administration of erythromycin estolate and erythromycin stearate. 1971 Med. J. Aust. pmid:5134726
Givan CV and Stumpf PK Fat Metabolism in Higher Plants: XLV. Some Factors Regulating Fatty Acid Synthesis by Isolated Spinach Chloroplasts. 1971 Plant Physiol. pmid:16657651
Smith DD Clinical trial of erythromycin stearate suspension. 1971 Med. J. Aust. pmid:5577264
Carlisle HN and Saslaw S Therapy of staphylococcal infections in monkeys. VI. Comparison of clindamycin, erythromycin, and methicillin. 1971 Appl Microbiol pmid:4994902
Nossel HL et al. Inhibition of collagen-induced platelet aggregation by normal plasma. 1971 J. Clin. Invest. pmid:4107268
SHABANOVA IA MYOCARDIAL FATTY ACIDS IN NORMAL RABBITS AND RABBITS WITH EXPERIMENTAL MYOCARDITIS. 1965 Mar-Apr Fed Proc Transl Suppl pmid:14304768
TINOCO J et al. LIVER LIPIDS OF CHOLINE-DEFICIENT RATS. 1965 Biochem. J. pmid:14345885
BOUCROT P and CLEMENT J [METABOLIC TRANSFORMATIONS SUSTAINED BY PALMITIC AND STEARIC ACIDS DURING THEIR DIGESTION AND ABSORPTION]. 1965 Arch Sci Physiol (Paris) pmid:14348516
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KAPILOFF P et al. A COMPARISON OF THE DISPOSITION OF INTRAVENOUSLY-INJECTED, ALBUMIN-BOUND STEARIC ACID-1-C14 AND PALMITIC ACID-1-C14 IN THE RAT. 1965 Proc. Soc. Exp. Biol. Med. pmid:14264563
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TOMPKINS MJ and DAYTON S RELATIONSHIP OF WHOLE BLOOD CLOTTING TIME TO PHYSIOLOGICAL VARIATIONS IN CIRCULATING SATURATED FREE FATTY ACIDS. 1965 Proc. Soc. Exp. Biol. Med. pmid:14328950
NEWLAND J et al. PHOSPHORUS METABOLISM IN VIRAL-INDUCED NEOPLASIA. II. IN VIVO AND IN VITRO STUDIES OF THE MILK AND MAMMARY GLAND LIPIDES OF STRAINS OF MICE SUSCEPTIBLE TO THE MAMMARY TUMOR VIRUS. 1965 Can. J. Biochem. pmid:14329900
NOBLE RC and MOORE JH FURTHER STUDIES ON THE LIPID METABOLISM OF THE NORMAL AND VITAMIN B-12 DEFICIENT CHICK EMBRYO. 1965 Biochem. J. pmid:14333549
WINTER CA and FLATAKER L NOCICEPTIVE THRESHOLDS AS AFFECTED BY PARENTERAL ADMINISTRATION OF IRRITANTS AND OF VARIOUS ANTINOCICEPTIVE DRUGS. 1965 J. Pharmacol. Exp. Ther. pmid:14334273
DICOSTANZO G and CLEMENT J ["IN VIVO" INCORPORATION OF TRITIATED OLEIC, STEARIC AND PALMITIC ACIDS INTO LIPIDS OF RAT INTESTINAL LUMEN AND MUCOSA. IMPORTANCE OF SUPPLY OF ENDOGENOUS FATTY ACIDS]. 1965 Bull. Soc. Chim. Biol. pmid:14334811
SRIDHARA S and BHAT JV FURTHER INVESTIGATIONS OF THE INCORPORATION OF (1-14C)ACETATE INTO THE LIPIDS OF THE SILKWORM BOMBYX MORI L. 1965 Biochem. J. pmid:14340061
BOUCROT P and CLEMENT J [SUPPLY OF ENDOGENOUS FATTY ACIDS IN RAT LYMPH FOLLOWING ADMINISTRATION OF A MEAL CONTAINING MIXED C14-STEARIC: H3-OLEIC TRIGLYCERIDES]. 1965 C. R. Hebd. Seances Acad. Sci. pmid:14341956
ANSTALL HB and TRUJILLO JM DETERMINATION OF FREE FATTY ACIDS IN PLASMA BY A COLORIMETRIC PROCEDURE: AN APPRAISAL OF THE METHOD AND COMPARISON WITH OTHER TECHNICS. 1965 Clin. Chem. pmid:14319230
SHAFRIR E et al. PARTITION OF FATTY ACIDS OF 20-24 CARBON ATOMS BETWEEN SERUM ALBUMIN AND LIPOPROTEINS. 1965 Biochim. Biophys. Acta pmid:14320230
GOERANSSON G THE METABOLISM OF FATTY ACIDS IN THE RAT. IV. STEARIC ACID. 1965 Acta Physiol. Scand. pmid:14321752
BRZIN B COMPARATIVE STUDIES ON ANAEROBIC CORYNEBACTERIA AND ACTINOMYCETES. 1965 Acta Pathol Microbiol Scand pmid:14322324
NORKIN SA et al. EFFECT OF ALBUMIN AND FATTY ACIDS ON CELLULAR GROWTH IN VITRO. 1965 Arch Pathol pmid:14322948
VADEHRA DV and HARMON LG ACTION OF LIPASES OF STAPHYLOCOCCUS AUREUS ON MILK FAT. 1965 Appl Microbiol pmid:14325270
ELOVSON J CHAIN-SHORTENING OF STEARIC ACID IN THE INTACT RAT. 1965 Biochim. Biophys. Acta pmid:14290835
BOYD EN et al. IRRELATION OF KETO STEARIC ACIDS TO FATTY ACID METABOLISM IN THE RUMINANT MAMMARY GLAND. 1965 J. Dairy Sci. pmid:14292229
MCCARTHY RD et al. THE CONVERSION OF STEARIC ACID TO OLEIC IN FRESHLY SECRETED MILK. 1965 Biochim. Biophys. Acta pmid:14292868
SCHROEPFER GJ ENZYMATIC STEREOSPECIFICITY IN THE CONVERSION OF OLEIC ACID TO 10-HYDROXYSTERARIC ACID. 1965 J. Am. Chem. Soc. pmid:14293763
SNYDER F and WRIGHT R EFFECT OF LOCALIZED IRRADIATION ON THE METABOLISM OF BONE-MARROW LIPIDS. 1965 Radiat. Res. pmid:14295131
AMENTA JS and DOMINGUEZ AM FATTY ACID FLUX AND TRIGLYCERIDE SECRETION IN THE HYDRAZINE-INDUCED FATTY LIVER. 1965 Exp. Mol. Pathol. pmid:14300114
SAGGESE EJ et al. URETHANE FOAMS FROM ANIMAL FATS. I. OXYETHYLATED 9, 10-DIHYDROXYSTEARIC ACID. 1965 J Am Oil Chem Soc pmid:14300211
GLENDE EA and CORNATZER WE FATTY ACID COMPOSITION OF RAT LIVER LIPIDS DURING CHOLINE DEFICIENCY. 1965 J. Nutr. pmid:14302120