stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Ghaly ES et al. Controlled release of theophylline from inert matrices: effect of channeling material on release rate. 1993 P R Health Sci J pmid:8140202
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Patil GS and Cornwell DG Surface phase separation and collapse of the stearate anion--alkaline earth cation complex. 1977 J. Lipid Res. pmid:833501
Muriana FJ et al. Lipid and fatty acid composition of hepatopancreatic brush-border membrane vesicles from the prawn Penaeus japonicus. 1993 J. Biochem. pmid:8340355
Monsma CC and Ney DM Interrelationship of stearic acid content and triacylglycerol composition of lard, beef tallow and cocoa butter in rats. 1993 Lipids pmid:8355579
Lurie E et al. N-(2-hydroxybenzyl)-omega-amino carbonic acids and their derivatives as tools for biochemical and biophysical investigations. 1993 Biochem. Mol. Biol. Int. pmid:8358340
Zock PL et al. Effects of stearic acid and trans fatty acids versus linoleic acid on blood pressure in normotensive women and men. 1993 Eur J Clin Nutr pmid:8365385
Cisar LA et al. Interleukin-1 selectively potentiates bradykinin-stimulated arachidonic acid release from human synovial fibroblasts. 1993 Cell. Signal. pmid:8373725
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Wada H et al. In vitro ferredoxin-dependent desaturation of fatty acids in cyanobacterial thylakoid membranes. 1993 J. Bacteriol. pmid:8419301
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Callaghan R et al. Increased accumulation of drugs in a multidrug resistant cell line by alteration of membrane biophysical properties. 1993 Biochim. Biophys. Acta pmid:8435444
Das T et al. Characterization of cardiac fatty-acid-binding protein from human placenta. Comparison with placenta hepatic types. 1993 Eur. J. Biochem. pmid:8436130
Poulos A et al. Fatty acid synthesis from [2-14C]acetate in normal and peroxisome-deficient (Zellweger) fibroblasts. 1993 Lipids pmid:8441343
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Nishihira J et al. Identification of the hydrophobic ligand-binding region in recombinant glutathione S-transferase P and its binding effect on the conformational state of the enzyme. 1993 Arch. Biochem. Biophys. pmid:8470890
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