| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Seizures | D012640 | 87 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| PANDE SV et al. | MICRODETERMINATION OF LIPIDS AND SERUM TOTAL FATTY ACIDS. | 1963 | Anal. Biochem. | pmid:14077635 |
| BURNS TW et al. | EFFECT OF INSULIN ON PLASMA FREE FATTY ACIDS OF NORMAL SUBJECTS. | 1963 | J. Lab. Clin. Med. | pmid:14080865 |
| CHAKRAVORTI KP and SADHU DP | STUDIES ON CHEMICAL COMPOSITION OF PROTEIN AND FAT IN THE OVIDUCT OF THE PIGEON, COLUMBA LIVIA GMELIN. | 1963 | Ann Biochem Exp Med | pmid:14082710 |
| STEIN O and STEIN Y | METABOLISM OF FATTY ACIDS IN THE ISOLATED PERFUSED RAT HEART. | 1963 | Biochim. Biophys. Acta | pmid:14085937 |
| LEVY G and GUMTOW RH | EFFECT OF CERTAIN TABLET FORMULATION FACTORS ON DISSOLUTION RATE OF THE ACTIVE INGREDIENT. III. TABLET LUBRICANTS. | 1963 | J Pharm Sci | pmid:14088962 |
| NAKAGAKI M and NISHINO M | [STUDIES ON THE PHYSICOCHEMICAL PROPERTIES OF ALUMINUM SOAPS. III. COMPOSITION OF ALUMINUM STEARATE AND STRUCTURAL VISCOSITY OF BENZENE SOLUTION]. | 1963 | Yakugaku Zasshi | pmid:14094211 |
| NAKAGAKI M and NISHINO M | [STUDIES ON THE PHYSICOCHEMICAL PROPERTIES OF ALUMINUM SOAPS. IV. EFFECT OF THERMAL TREATMENT ON THE STRUCTURE OF THE SOAP]. | 1963 | Yakugaku Zasshi | pmid:14094212 |
| LEAT WM | FATTY ACID COMPOSITION OF THE SERUM LIPIDS OF PIGS GIVEN DIFFERENT AMOUNTS OF LINOLEIC ACID. | 1963 | Biochem. J. | pmid:14097364 |
| HAJRA AK and RADIN NS | IN VIVO CONVERSION OF LABELED FATTY ACIDS TO THE SPHINGOLIPID FATTY ACIDS IN RAT BRAIN. | 1963 | J. Lipid Res. | pmid:14168188 |
| KUNUGI K | Studies on the syntheses of sucrose fatty acid esters. III. Re-esterification of sucrose monostearate. | 1963 | Chem. Pharm. Bull. | pmid:13927388 |
| NAKAGAKI M and NISHINO M | [Studies on the physicochemical properties of aluminum soap. II. Structural viscosity of aluminum stearate in benzene]. | 1963 | Yakugaku Zasshi | pmid:13937343 |
| OSTWALD R | Fat content and fatty acids in some commercial mixes for baked products. | 1963 | J Am Diet Assoc | pmid:13940620 |
| EDWARDS CH et al. | CHROMATOGRAPHY ON COMPOUNDS OF BIOLOGICAL INTEREST OF GLASS FIBER, PARAFFIN-COATED, AND UNTREATED CELLULOSE PAPER. | 1963 | J. Chromatogr. | pmid:14045492 |
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| DAVIDOFF F and KORN ED | Synthesis of unsaturated fatty acids in the cellular slime mold. | 1962 | Biochem. Biophys. Res. Commun. | pmid:14025332 |
| DEYKIN D and GOODMAN DS | The hydrolysis of long-chain fatty acid esters of cholesterol with rat liver enzymes. | 1962 | J. Biol. Chem. | pmid:14027461 |
| TROUT DL and ESTES EH | Factors affecting liver uptake of serum free stearic acid-1-C14. | 1962 | Am. J. Physiol. | pmid:13994303 |
| WALLEN LL et al. | The microbiological production of 10-hydroxystearic acid from oleic acid. | 1962 | Arch. Biochem. Biophys. | pmid:13998583 |
| CREASEY WA | Observations on the activation of stearic acid by rat-liver preparations. | 1962 | Biochim. Biophys. Acta | pmid:14023748 |
| JAMES AT | [Studies on the biosynthesis of 18 carbon mono-and tri-unsaturated fatty acids by gas phase chromatography]. | 1962 | Bull. Soc. Chim. Biol. | pmid:13957228 |
| FOSSA T | [Inhibition of hepatic glucose-6-phosphatase by fatty acids and zinc ions]. | 1962 | Boll. Soc. Ital. Biol. Sper. | pmid:13958874 |
| BARGONI N and SISINI A | [Inhibition and reactivation of the hydrolases of digestion]. | 1962 | Boll. Soc. Ital. Biol. Sper. | pmid:13966663 |
| NIELSEN K and SCHMIDT H | [Should the standard treatment of gonorrhea be changed? Effects of the treatment of gonorrhea in 1960 in ambulant and hospitalized patients]. | 1962 | Manedsskr Prakt Laegegern | pmid:13938514 |
| GUTIERREZ J et al. | Lipid metabolism of rumen ciliates and bacteria. I. Uptake of fatty acids by Isotricha prostoma and Entodinium simplex. | 1962 | Appl Microbiol | pmid:13951437 |
| FOTI L et al. | [In vitro liver biosynthesis of cholesterol from acetate, stearate and linoleate 1-C-14]. | 1961 | Boll. Soc. Ital. Biol. Sper. | pmid:13958917 |
| AGARWAL SC et al. | Blood-level duration limit test of procaine benzylpenicillin in sheep. | 1961 | Bull. World Health Organ. | pmid:13859560 |
| LIN TM et al. | Effect of stearic acid and cholesterol on biosynthesis of sterol by the chicken liver. | 1960 | Am. J. Physiol. | pmid:14417022 |
| SHANES AM and GERSHFELD NL | Interactions of veratrum alkaloids, procaine, and calcium with monolayers of stearic acid and their implications for pharmacological action. | 1960 | J. Gen. Physiol. | pmid:13750673 |
| GERSHFELD NL and SHANES AM | Antagonism of veratrine by calcium ion in monolayers of stearic acid. | 1959 | Science | pmid:13658972 |
| BLOMSTRAND R et al. | Asymmetric incorporation of linoleic acid-1-C14 and stearic acid-1-C14 into human lymph lecithins during fat absorption. | 1959 | Proc. Soc. Exp. Biol. Med. | pmid:13645714 |
| FITZHUGH OG et al. | Chronic oral toxicities of four stearic acid emulsifiers. | 1959 | Toxicol. Appl. Pharmacol. | pmid:13659539 |
| SKIPSKI VP et al. | Identification of 2-hydroxystearic acid in spinal cord phrenosine by chromatographic separation of hydroxy fatty acids. | 1959 | Arch. Biochem. Biophys. | pmid:13661981 |
| HURLEY HJ and SHELLEY WB | The colloidal state as a stimulus for non-allergic epithelioid granulomas: experimental studies in man with pure sodium stearate and palmitate. | 1959 | J. Invest. Dermatol. | pmid:14405513 |
| KELLERSHOHN C and BENICHOUX R | [Comparative study of the drainage through the lymphatic vessels of a radioactive fat, ethyl diiodosterate labeled with I 131, and a radioactive colloidal substance, colloidal gold 198]. | 1958 May-Jun | Minerva Nucl | pmid:13565747 |
| COX AJ and DEEDS F | Dietary production of lipogranuloma in rats. | 1958 Mar-Apr | Am. J. Pathol. | pmid:13520907 |
| LONG CL et al. | Studies on absorption and metabolism of propylene glycol distearate. | 1958 | Arch. Biochem. Biophys. | pmid:13584006 |
| LONG CL et al. | An investigation of the in vivo hydrolysis and absorption of propylene glycol distearate. | 1958 | Arch. Biochem. Biophys. | pmid:13584007 |
| CONIGLIO JG and CATE DL | The distribution and biosynthesis of palmitic and stearic acids in liver, intestine, and carcass of intact normal and fasted rats. | 1958 | J. Biol. Chem. | pmid:13549425 |
| DAWSON RM | The labelling of ram semen in vivo with radioactive phosphate and [carboxy-14C] stearic acid. | 1958 | Biochem. J. | pmid:13522653 |
| HARDING HE | Some enquiries into the toxicology of zinc stearate. | 1958 | Br J Ind Med | pmid:13523087 |
| RUTSTEIN DD et al. | Effects of linolenic and stearic acids on cholesterol-induced lipoid deposition in human aortic cells in tissue-culture. | 1958 | Lancet | pmid:13515277 |
| FABER JS | A note on the assay of zinc stearate. | 1957 | J Am Pharm Assoc Am Pharm Assoc | pmid:13491438 |
| BRZEZINSKI A et al. | Prolonged effect of riboflavin: aluminum monostearate suspensions in man. | 1957 | J Am Pharm Assoc Am Pharm Assoc | pmid:13438726 |
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| GLASCOCK RF and REINIUS LR | Studies on the origin of milk fat. 1. The location of tritium in stearic acid produced by the catalytic addition of tritium to elaidic acid. | 1956 | Biochem. J. | pmid:13315207 |
| TOVE SB et al. | Turnover of palmitic, stearic, and unsaturated fatty acids in rat liver. | 1956 | J. Biol. Chem. | pmid:13278335 |
| MEAD JF et al. | Metabolism of the essential fatty acids. II. The metabolism of stearate, oleate, and linoleate by fat-deficient and normal mice. | 1956 | J. Biol. Chem. | pmid:13278347 |
| BLOMSTRAND R et al. | On the intestinal absorption of 2, 2-dimethylstearic acid fed as free acid or as glyceride. | 1956 | Acta Physiol. Scand. | pmid:13339456 |
| KERN W et al. | [Suggestions for the composition of the general section on ointments and salve bases and emulsifiers in the German Pharmacopeia (DAB 6, Annex). II]. | 1956 | Hautarzt | pmid:13345190 |