stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Brain Edema D001929 20 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Di Vaio C et al. Influence of some environmental factors on drupe maturation and olive oil composition. 2013 J. Sci. Food Agric. pmid:22936522
Baek JS and Cho CW 2-Hydroxypropyl-β-cyclodextrin-modified SLN of paclitaxel for overcoming p-glycoprotein function in multidrug-resistant breast cancer cells. 2013 J. Pharm. Pharmacol. pmid:23215690
Hu P et al. Genotoxicity evaluation of stearic acid grafted chitosan oligosaccharide nanomicelles. 2013 Mutat. Res. pmid:23274307
Wu X et al. Alkanethiol-functionalized terahertz metamaterial as label-free, highly-sensitive and specific biosensor. 2013 Biosens Bioelectron pmid:23261700
Gotoh K et al. Evaluation of removal of model particulate and oily soils from poly(ethylene terephthalate) films by microscopic image analysis. 2013 J Oleo Sci pmid:23391530
Fernandes CP et al. Triterpene esters and biological activities from edible fruits of Manilkara subsericea (Mart.) Dubard, Sapotaceae. 2013 Biomed Res Int pmid:23509702
You J et al. Specific tumor delivery of paclitaxel using glycolipid-like polymer micelles containing gold nanospheres. 2013 Biomaterials pmid:23510855
John CT et al. Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate. 2013 Pharm. Res. pmid:23512680
Stank K and Steckel H Physico-chemical characterisation of surface modified particles for inhalation. 2013 Int J Pharm pmid:23518364
Hagen RM et al. Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent. 2013 Anticancer Res. pmid:24123008
Guo H et al. Self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates for delivery of doxorubicin. 2013 Int J Pharm pmid:24140544
Cvetković Z et al. Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin's lymphoma patients. 2013 Med. Oncol. pmid:24085546
Jin Q et al. A novel cationic microbubble coated with stearic acid-modified polyethylenimine to enhance DNA loading and gene delivery by ultrasound. 2013 PLoS ONE pmid:24086748
Eltayeb M et al. Electrosprayed core-shell polymer-lipid nanoparticles for active component delivery. 2013 Nanotechnology pmid:24164775
Li P et al. Effect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro. 2013 Cell. Physiol. Biochem. pmid:24335176
Wahl PR et al. Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion. 2013 Int J Pharm pmid:23911343
Michailidou VN et al. Anisotropic diffusion of concentrated hard-sphere colloids near a hard wall studied by evanescent wave dynamic light scattering. 2013 J Chem Phys pmid:24182077
Hosseini A et al. Direct compression of cushion-layered ethyl cellulose-coated extended release pellets into rapidly disintegrating tablets without changes in the release profile. 2013 Int J Pharm pmid:23892153
Tammaro A et al. Magnesium stearate: an underestimated allergen. 2012 Oct-Dec J. Biol. Regul. Homeost. Agents pmid:23241129
Hentzschel CM et al. Comparison of traditional and novel tableting excipients: physical and compaction properties. 2012 Nov-Dec Pharm Dev Technol pmid:21740091
Khan FN and Dehghan MH Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. 2012 Jan-Mar Sci Pharm pmid:22396916
Pujeri SS et al. Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. 2012 Jan-Mar Sci Pharm pmid:22396908
Aling J and Podczeck F The filling of powdered herbs into two-piece hard capsules using hydrogenated cotton seed oil as lubricant. 2012 Eur J Pharm Sci pmid:22960627
Kottala N et al. Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets. 2012 AAPS PharmSciTech pmid:22965660
Al-Ghamdi AF et al. Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids. 2012 Chem Cent J pmid:22353684
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Walash MI et al. Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma. 2012 Chem Cent J pmid:22333299
Darwish IA et al. Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate. 2012 Chem Cent J pmid:22305461
Sharma A and Chauhan RS In silico identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants. 2012 Comp. Funct. Genomics pmid:22312320
Patel K et al. Duloxetine HCl lipid nanoparticles: preparation, characterization, and dosage form design. 2012 AAPS PharmSciTech pmid:22167415
Zhang J et al. Synthesis of NaYF(4):Yb/Er/Gd up-conversion luminescent nanoparticles and luminescence resonance energy transfer-based protein detection. 2012 Anal. Biochem. pmid:22155069
Pawar AA et al. Influence of precursor solvent properties on matrix crystallinity and drug release rates from nanoparticle aerosol lipid matrices. 2012 Int J Pharm pmid:22469694
Zhu S et al. Lysosomal delivery of a lipophilic gemcitabine prodrug using novel acid-sensitive micelles improved its antitumor activity. 2012 Bioconjug. Chem. pmid:22471294
Wajid NA and Halpern BP Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. 2012 Chem. Senses pmid:22459162
Gröblacher B et al. Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis. 2012 Bioorg. Med. Chem. pmid:22459211
Nakagawa H et al. Evaluation of infrared-reflection absorption spectroscopy measurement and locally weighted partial least-squares for rapid analysis of residual drug substances in cleaning processes. 2012 Anal. Chem. pmid:22449097
Das SC and Stewart PJ Characterising surface energy of pharmaceutical powders by inverse gas chromatography at finite dilution. 2012 J. Pharm. Pharmacol. pmid:22881445
Hu SY et al. [Studies on sustained release solid dispersion of tripterine carried by HPMC-stearic acid]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23311152
Yavuz B et al. An overview on dry eye treatment: approaches for cyclosporin a delivery. 2012 ScientificWorldJournal pmid:22619624
Tuli RA et al. Studies on the effect of the size of polycaprolactone microspheres for the dispersion of salbutamol sulfate from dry powder inhaler formulations. 2012 Pharm. Res. pmid:22584947
Itoh Y and Hasegawa T Polarization dependence of Raman scattering from a thin film involving optical anisotropy theorized for molecular orientation analysis. 2012 J Phys Chem A pmid:22551093
Gellrich V et al. Behavior of perfluorinated compounds in soils during leaching experiments. 2012 Chemosphere pmid:22391048
Muro M et al. Molecular rearrangement in a zinc stearate Langmuir film dependent on a film preparation method studied using polarization-modulation infrared reflection absorption spectroscopy and X-ray absorption fine structure. 2012 J Phys Chem B pmid:22339471
Dawes J et al. An investigation into the impact of magnesium stearate on powder feeding during roller compaction. 2012 Drug Dev Ind Pharm pmid:21810064
Guo C et al. In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. 2012 J Nanosci Nanotechnol pmid:22523972
Shah KU and Khan GM Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. 2012 ScientificWorldJournal pmid:22649325
Polizzotti BD et al. Intrapericardial delivery of gelfoam enables the targeted delivery of Periostin peptide after myocardial infarction by inducing fibrin clot formation. 2012 PLoS ONE pmid:22590609
Song IS et al. Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition. 2012 PLoS ONE pmid:22590580
Ahmed TA et al. Miconazole nitrate oral disintegrating tablets: in vivo performance and stability study. 2012 AAPS PharmSciTech pmid:22585373
Varshosaz J et al. Development and evaluation of a novel pellet-based tablet system for potential colon delivery of budesonide. 2012 J Drug Deliv pmid:22577558