stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Brain Edema D001929 20 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Birth Weight D001724 23 associated lipids
Breast Neoplasms D001943 24 associated lipids
Cattle Diseases D002418 24 associated lipids
Insulinoma D007340 28 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Dermatitis D003872 30 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Gängler P et al. In vitro effect of fluoride oral hygiene tablets on artificial caries lesion formation and remineralization in human enamel. 2009 BMC Oral Health pmid:19799785
Stahl J et al. The effect of formulation vehicles on the in vitro percutaneous permeation of ibuprofen. 2011 BMC Pharmacol. pmid:22168832
Larsson KE et al. LysoPC acyltransferase/PC transacylase activities in plant plasma membrane and plasma membrane-associated endoplasmic reticulum. 2007 BMC Plant Biol. pmid:18045483
Mayer KM and Shanklin J Identification of amino acid residues involved in substrate specificity of plant acyl-ACP thioesterases using a bioinformatics-guided approach. 2007 BMC Plant Biol. pmid:17201914
Du H et al. Modification of the fatty acid composition in Arabidopsis and maize seeds using a stearoyl-acyl carrier protein desaturase-1 (ZmSAD1) gene. 2016 BMC Plant Biol. pmid:27297560
Gillman JD et al. Deletions of the SACPD-C locus elevate seed stearic acid levels but also result in fatty acid and morphological alterations in nitrogen fixing nodules. 2014 BMC Plant Biol. pmid:24886084
Singh R et al. Mapping quantitative trait loci (QTLs) for fatty acid composition in an interspecific cross of oil palm. 2009 BMC Plant Biol. pmid:19706196
Li D et al. Ruminal microbe of biohydrogenation of trans-vaccenic acid to stearic acid in vitro. 2012 BMC Res Notes pmid:22336099
Lavigne JP et al. Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections. 2011 BMC Res Notes pmid:22126300
Harding SV et al. Desaturation index versus isotopically measured de novo lipogenesis as an indicator of acute systemic lipogenesis. 2015 BMC Res Notes pmid:25879456
Fang X et al. Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. 2010 BMC Syst Biol pmid:21092312
Kusano M et al. Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana. 2007 BMC Syst Biol pmid:18028551
Ip K et al. Analysis of complex metabolic behavior through pathway decomposition. 2011 BMC Syst Biol pmid:21639889
Huthmacher C et al. Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. 2010 BMC Syst Biol pmid:20807400
Stanley JC VAT and fat. Taxing single nutrient is dangerous. 2000 BMJ pmid:10877557
Springolo V [Bioavailability of formulations containing erythromycin base or stearate in soft enteric gelatin capsules]. 1978 Boll Chim Farm pmid:743360
Pedrazzi V et al. Tensile bond strength of a polymeric intra-buccal bioadhesive: the mucin role. 2001 Nov-Dec Boll Chim Farm pmid:11822242
Caponnetto A et al. [Correlations between unsaturated fatty acids and medium C-chain triglycerides]. 1986 Boll. Soc. Ital. Biol. Sper. pmid:3718739
FOSSA T [Inhibition of hepatic glucose-6-phosphatase by fatty acids and zinc ions]. 1962 Boll. Soc. Ital. Biol. Sper. pmid:13958874
FOTI L et al. [In vitro liver biosynthesis of cholesterol from acetate, stearate and linoleate 1-C-14]. 1961 Boll. Soc. Ital. Biol. Sper. pmid:13958917
BARGONI N and SISINI A [Inhibition and reactivation of the hydrolases of digestion]. 1962 Boll. Soc. Ital. Biol. Sper. pmid:13966663
Uzunović A and Vranić E Effect of magnesium stearate concentration on dissolution properties of ranitidine hydrochloride coated tablets. 2007 Bosn J Basic Med Sci pmid:17848158
Rutland J et al. The influence of food on the bioavailability of new formulations of erythromycin stearate and base. 1979 Br J Clin Pharmacol pmid:508509
Josefsson K et al. Dose-related pharmacokinetics after oral administration of a new formulation of erythromycin base. 1982 Br J Clin Pharmacol pmid:7082537
Mather LE et al. Absorption and bioavailability of oral erythromycin. 1981 Br J Clin Pharmacol pmid:7306427
ZUCKERMAN AJ and MACDONAID L THE ROLE OF DIETARY CARBOHYDRATES AND INFECTION ON LIVER LIPID AND COLLAGEN. 1964 Br J Exp Pathol pmid:14245158
HOAK JC STRUCTURE OF THROMBI PRODUCED BY INJECTIONS OF FATTY ACIDS. 1964 Br J Exp Pathol pmid:14119273
CORRIN B ALUMINIUM PNEUMOCONIOSIS. I. IN VITRO COMPARISON OF STAMPED ALUMINIUM POWDERS CONTAINING DIFFERENT LUBRICATING AGENTS AND A GRANULAR ALUMINIUM POWDER. 1963 Br J Ind Med pmid:14072616
CORRIN B ALUMINIUM PNEUMOCONIOSIS. II. EFFECT ON THE RAT LUNG OF INTRATRACHEAL INJECTIONS OF STAMPED ALUMINIUM POWDERS CONTAINING DIFFERENT LUBRICATING AGENTS AND OF A GRANULAR ALUMINIUM POWDER. 1963 Br J Ind Med pmid:14072617
HARDING HE Some enquiries into the toxicology of zinc stearate. 1958 Br J Ind Med pmid:13523087
Persad RA et al. Erythrocyte stearic to oleic acid ratio in prostatic carcinoma. 1990 Br J Urol pmid:2337746
Duncan MO et al. Treatment of chancroid with erythromycin. A clinical and microbiological appraisal. 1983 Br J Vener Dis pmid:6603249
Arya OP and Bosa CB In search of an ideal single-session penicillin schedule for the treatment of gonorrhoea in Uganda. 1973 Br J Vener Dis pmid:4748409
Iliopoulou A et al. Fluorimetric and microbiological assays of erythromycin concentrations in plasma and vaginal washings. 1981 Br J Vener Dis pmid:7272705
Polnikorn N et al. Penicillin concentrations in cerebrospinal fluid after different treatment regimens for syphilis. 1980 Br J Vener Dis pmid:7448578
Boakes AJ et al. Treatment of uncomplicated gonorrhoea in women with a combination of rifampicin and erythromycin. 1984 Br J Vener Dis pmid:6487986
Hunter JM and Sommerville RG Erythromycin stearate in treating chlamydial infection of the cervix. 1984 Br J Vener Dis pmid:6518350
WAYNE EJ et al. The use of procaine penicillin with aluminium monostearate in adults. 1949 Br Med J pmid:15407914
EMERY JL and ROSE LM The use in children of procaine penicillin with aluminium monostearate. 1949 Br Med J pmid:18145953
Inman WH and Rawson NS Erythromycin estolate and jaundice. 1983 Br Med J (Clin Res Ed) pmid:6407653
Søreide O et al. Inadequacy of oleic acid in erythrocytes as a marker of malignancies. 1987 Br Med J (Clin Res Ed) pmid:3103770
Wood CB et al. Increase of oleic acid in erythrocytes associated with malignancies. 1985 Br Med J (Clin Res Ed) pmid:3926106
Nkondjock A et al. Specific fatty acid intake and the risk of pancreatic cancer in Canada. 2005 Br. J. Cancer pmid:15685231
Lee WN et al. Metabolic sensitivity of pancreatic tumour cell apoptosis to glycogen phosphorylase inhibitor treatment. 2004 Br. J. Cancer pmid:15599384
Hussey HJ and Tisdale MJ Mechanism of the anti-tumour effect of 2,3,5-trimethyl-6-(3-pyridylmethyl) 1,4-benzoquinone (CV-6504). 1997 Br. J. Cancer pmid:9062405
Wall L et al. A phase I and pharmacological study of the matrix metalloproteinase inhibitor BB-3644 in patients with solid tumours. 2004 Br. J. Cancer pmid:14970856
Sauer LA and Dauchy RT Uptake of plasma lipids by tissue-isolated hepatomas 7288CTC and 7777 in vivo. 1992 Br. J. Cancer pmid:1503901
BOYLAND E et al. FURTHER EXPERIMENTS ON IMPLANTATION OF MATERIALS INTO THE URINARY BLADDER OF MICE. 1964 Br. J. Cancer pmid:14219552
Chaudry A et al. Essential fatty acid distribution in the plasma and tissue phospholipids of patients with benign and malignant prostatic disease. 1991 Br. J. Cancer pmid:1764380
BONSER GM et al. A further study of bladder implantation in the mouse as a means of detecting carcinogenic activity: use of crushed paraffin wax or stearic acid as the vehicle. 1963 Br. J. Cancer pmid:13968883