stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Brain Edema D001929 20 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Birth Weight D001724 23 associated lipids
Breast Neoplasms D001943 24 associated lipids
Cattle Diseases D002418 24 associated lipids
Insulinoma D007340 28 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Dermatitis D003872 30 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Garcia Zevallos M and Farkas T Manipulation of plasma membrane physical state affects desaturase activity in rat lymphocytes. 1989 Arch. Biochem. Biophys. pmid:2786374
Wada M et al. Mechanism of biosynthesis of unsaturated fatty acids in Pseudomonas sp. strain E-3, a psychrotrophic bacterium. 1989 J. Bacteriol. pmid:2753856
Friedman E et al. Fecal diglycerides as selective endogenous mitogens for premalignant and malignant human colonic epithelial cells. 1989 Cancer Res. pmid:2910475
Shires SE et al. Effects of linoleic acid and mitogenic stimulation on the fatty acid composition of human lymphocytes. 1989 Biochim. Biophys. Acta pmid:2493807
Severin SE et al. Synapsin I from human brain. Phosphorylation by Ca2+, phospholipid-dependent protein kinase. 1989 FEBS Lett. pmid:2513229
Adeyeye A et al. Studies on the antigenic S-type lipopolysaccharides of Brucella abortus strains 7 and Mustapha. 1989 Int. J. Biol. Macromol. pmid:2518732
Simpson JT et al. Identification of major lipids from the scent gland secretions of Dumeril's ground boa (Acrantophis dumerili Jan) by gas chromatography-mass spectrometry. 1988 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:3245880
Hoppe JE and Haug A Treatment and prevention of pertussis by antimicrobial agents (Part II). 1988 May-Jun Infection pmid:3042626
Hoeg JM et al. Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation. 1988 J. Lipid Res. pmid:2846736
Avila P et al. Which salt of erythromycin is most hepatotoxic? 1988 Lancet pmid:2896928
Jones RE and Plymate SR Evidence for the regulation of fatty acid utilization in human sperm by docosahexaenoic acid. 1988 Biol. Reprod. pmid:2905175
Van Rafelghem MJ and Andersen ME The effects of perfluorodecanoic acid on hepatic stearoyl-coenzyme A desaturase and mixed function oxidase activities in rats. 1988 Fundam Appl Toxicol pmid:2906022
Baichwal AR and Augsburger LL Variations in the friction coefficients of tablet lubricants and relationship to their physicochemical properties. 1988 J. Pharm. Pharmacol. pmid:2907013
Longmuir KJ and Rossi ME Fatty acid chain-shortening activity in the pulmonary type II cell. 1988 Biochim. Biophys. Acta pmid:3289622
Schmid KM and Patterson GW Effects of cyclopropenoid fatty acids on fungal growth and lipid composition. 1988 Lipids pmid:3131612
Chu SH and Walker WA Development of the gastrointestinal mucosal barrier: changes in phospholipid head groups and fatty acid composition of intestinal microvillus membranes from newborn and adult rats. 1988 Pediatr. Res. pmid:3131728
Kaya K and Kusumi T Isolation and structural characterization of a diacyltaurolipid in cells of Tetrahymena mimbres. 1988 Biochim. Biophys. Acta pmid:3132980
Aho P and Männistö PT Effects of two erythromycins, doxycycline and phenoxymethylpenicillin on human leucocyte chemotaxis in vitro. 1988 J. Antimicrob. Chemother. pmid:3134323
Kraus G et al. [The modification of different element levels in human blood by occupational cadmium exposure]. 1988 Zentralbl Bakteriol Mikrobiol Hyg B pmid:3138836
Abbott AA et al. A prospective randomized trial on efficacy of antibiotic prophylaxis in asymptomatic teeth with pulpal necrosis and associated periapical pathosis. 1988 Oral Surg. Oral Med. Oral Pathol. pmid:3144686
Takenaka T et al. Effects of arachidonic acid and the other long-chain fatty acids on the membrane currents in the squid giant axon. 1988 J. Membr. Biol. pmid:3147335
Bach R et al. Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine. 1988 Biochemistry pmid:3166978
Ertel KD and Carstensen JT Chemical, physical, and lubricant properties of magnesium stearate. 1988 J Pharm Sci pmid:3171951
Effect of dietary stearic acid on plasma cholesterol level. 1988 N. Engl. J. Med. pmid:3173438
de Groot AC et al. Cosmetic allergy from stearic acid and glyceryl stearate. 1988 Contact Derm. pmid:3180776
Ricevuti G et al. Serum, sputum and bronchial concentrations of erythromycin in chronic bronchitis after single and multiple treatments with either propionate-N-acetylcysteinate or stearate erythromycin. 1988 Chemotherapy pmid:3180905
Morasso MI et al. Effect of mixing on the biopharmaceutical properties of sulfadiazine tablets. 1988 Farmaco Prat pmid:3181415
Korkeala H and Männistö PT Time course of the antibacterial activity of erythromycin stearate and erythromycin acistrate against two Staphylococcus aureus strains in vitro. 1988 J. Antimicrob. Chemother. pmid:3182415
Demediuk P et al. Traumatic brain injury in the rat: effects on lipid metabolism, tissue magnesium, and water content. 1988 J. Neurotrauma pmid:3066912
Nahata MC Selection of an erythromycin for the treatment of pertussis. 1988 Drug Intell Clin Pharm pmid:3069427
Ciszewski A and Lukaszewski Z Electrochemical masking for removal of the titanium matrix effect in DPASV determination of thallium. 1988 Talanta pmid:18964494
Huang G et al. Identification of the thiol ester linked lipids in apolipoprotein B. 1988 Biochemistry pmid:3365394
Periquet B et al. Fatty acid composition and kinetic behaviour of liver retinyl esters in vitamin A sufficient and deficient rats. 1988 Clin. Chim. Acta pmid:3370842
Brodersen R et al. Palmitate binding to serum albumin, measured by rate of dialysis. 1988 Eur. J. Biochem. pmid:3371363
Slinger AJ and Isaac RE Synthesis of apolar ecdysone esters by ovaries of the cockroach Periplaneta americana. 1988 Gen. Comp. Endocrinol. pmid:3371652
Roberts L Beef and chocolate: a partial reprieve. 1988 Science pmid:3375809
Salo OP et al. Efficacy and tolerability of erythromycin acistrate and erythromycin stearate in acute skin infections of patients with atopic eczema. 1988 J. Antimicrob. Chemother. pmid:3391871
Rostila T et al. Erythromycin acistrate and erythromycin stearate in the treatment of non-gonococcal urethritis. 1988 J. Antimicrob. Chemother. pmid:3391873
Männistö PT et al. Fate of single oral doses of erythromycin acistrate, erythromycin stearate and pelleted erythromycin base analysed by mass-spectrometry in plasma of healthy human volunteers. 1988 J. Antimicrob. Chemother. pmid:3391874
Savolainen S et al. Tonsillar penetration of erythromycin and its 2'-acetyl ester in patients with chronic tonsillitis. 1988 J. Antimicrob. Chemother. pmid:3391878
Viluksela M et al. Comparative liver toxicity of various erythromycin derivatives in animals. 1988 J. Antimicrob. Chemother. pmid:3391880
Ogata S et al. Chemical characterization of the membrane-anchoring domain of human placental alkaline phosphatase. 1988 J. Biol. Chem. pmid:3392021
Pitt WG and Cooper SL Albumin adsorption on alkyl chain derivatized polyurethanes: I. The effect of C-18 alkylation. 1988 J. Biomed. Mater. Res. pmid:3397377
Rahman MD et al. Effects of sulfur-containing analogues of stearic acid on growth and fatty acid biosynthesis in the protozoan Crithidia fasciculata. 1988 J. Med. Chem. pmid:3398003
Trinchera M et al. Different metabolic recycling of the lipid components of exogenous sulphatide in human fibroblasts. 1988 Biochem. J. pmid:3415659
Bull AW et al. Structural requirements for stimulation of colonic cell proliferation by oxidized fatty acids. 1988 Cancer Res. pmid:3349456
Sanjurjo P et al. Plasma fatty acid composition during the first week of life following feeding with human milk or formula. 1988 Acta Paediatr Scand pmid:3354331
Graham A et al. Fatty acid specificity for the synthesis of triacylglycerol and phosphatidylcholine and for the secretion of very-low-density lipoproteins and lysophosphatidylcholine by cultures of rat hepatocytes. 1988 Biochem. J. pmid:3355493
Bonanome A and Grundy SM Effect of dietary stearic acid on plasma cholesterol and lipoprotein levels. 1988 N. Engl. J. Med. pmid:3362176
Rosenberg IH and Schaefer EJ Dietary saturated fatty acids and blood cholesterol. 1988 N. Engl. J. Med. pmid:3362180
Cevc G et al. Phosphatidylcholine-fatty acid membranes. I. Effects of protonation, salt concentration, temperature and chain-length on the colloidal and phase properties of mixed vesicles, bilayers and nonlamellar structures. 1988 Biochim. Biophys. Acta pmid:2835979
Zanetti R and Catalá A Lipid binding properties of fatty acid binding protein isolated from mouse liver. 1988 Acta Physiol Pharmacol Latinoam pmid:3201993
Nakayoshi T et al. Comparative study on effects of 14- and 16-membered macrolides on gastrointestinal motility in unanaesthetized dogs. 1988 Drugs Exp Clin Res pmid:3265375
Yeh YY Long chain fatty acid deficits in brain myelin sphingolipids of undernourished rat pups. 1988 Lipids pmid:3226227
Broderick PA Distinguishing in vitro electrochemical signatures for norepinephrine and dopamine. 1988 Neurosci. Lett. pmid:3226613
Ubels JL et al. Vitamin A is stored as fatty acyl esters of retinol in the lacrimal gland. 1988 Curr. Eye Res. pmid:3229120
McNulty CA et al. Inhibitory antimicrobial concentrations against Campylobacter pylori in gastric mucosa. 1988 J. Antimicrob. Chemother. pmid:3209531
Tan S et al. Gas chromatographic determination of calcium stearate in polyethylene food packaging sheets. 1988 J. Chromatogr. pmid:3209663
Sparace SA et al. A preliminary analysis of Fatty Acid synthesis in pea roots. 1988 Plant Physiol. pmid:16666088
Horváth LI et al. Exchange rates at the lipid-protein interface of myelin proteolipid protein studied by spin-label electron spin resonance. 1988 Biochemistry pmid:2450570
Heyman SN et al. Erythromycin-induced dynamic ileus? 1988 J. Clin. Gastroenterol. pmid:3183328
Loscalzo J et al. Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells. 1987 Sep-Oct Arteriosclerosis pmid:3675304
Shani J et al. Efficacy of sustained-release radioprotective drugs in vivo. 1987 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:2966504
Kringsholm B and Christoffersen P The nature and the occurrence of birefringent material in different organs in fatal drug addiction. 1987 May-Jun Forensic Sci. Int. pmid:3036675
Udod VM et al. [Microbial breakdown of stearox-6 and a study of the genetic determination of the nature of the degradative activity]. 1987 May-Jun Mikrobiol. Zh. pmid:3150493
Fatemi SH et al. The glycophospholipid anchor of Thy-1. Biosynthetic labeling experiments with wild-type and class E Thy-1 negative lymphomas. 1987 J. Biol. Chem. pmid:2881925
West AA et al. The relationship between glycosyltransferase production and membrane fatty acid composition of Streptococcus sanguis NCTC 7865 grown in the presence of protonmotive force inhibitors. 1987 J. Gen. Microbiol. pmid:2966234
Ondrias K et al. Spin label study of the perturbation effect of the local anaesthetics tetracaine and dibucaine on synaptosomes at pharmacological concentrations. 1987 Biochem. Pharmacol. pmid:2825709
Reddy TS and Bazan NG Arachidonic acid, stearic acid, and diacylglycerol accumulation correlates with the loss of phosphatidylinositol 4,5-bisphosphate in cerebrum 2 seconds after electroconvulsive shock: complete reversion of changes 5 minutes after stimulation. 1987 J. Neurosci. Res. pmid:2830409
Ogata S et al. Chemical identification of lipid components in the membranous form of rat liver alkaline phosphatase. 1987 J. Biochem. pmid:2834351
Swendsen CL et al. Human neutrophils incorporate arachidonic acid and saturated fatty acids into separate molecular species of phospholipids. 1987 Biochim. Biophys. Acta pmid:3105590
DeGeorge JJ et al. Acetylcholine stimulates selective liberation and re-esterification of arachidonate and accumulation of inositol phosphates and glycerophosphoinositol in C62B glioma cells. 1987 J. Biol. Chem. pmid:3110145
Morse DR et al. Infectious flare-ups and serious sequelae following endodontic treatment: a prospective randomized trial on efficacy of antibiotic prophylaxis in cases of asymptomatic pulpal-periapical lesions. 1987 Oral Surg. Oral Med. Oral Pathol. pmid:3112672
Crost S et al. Hormonal effects on mitochondrial respiration: potential role of endogenous lipolytic activities. 1987 Arch. Biochem. Biophys. pmid:3113334
Halát G et al. Effects of incomplete ischemia and subsequent recirculation on free palmitate, stearate, oleate and arachidonate levels in lumbar and cervical spinal cord of rabbit. 1987 Gen. Physiol. Biophys. pmid:3117617
Hohl C and Rösen P Arachidonic acid metabolism in isolated rat heart myocytes. 1987 Prog. Clin. Biol. Res. pmid:3118380
Taylor AJ et al. An alternative explanation for the changes in erythrocyte fatty acids observed in diabetes mellitus. 1987 Clin. Chem. pmid:3119255
Shanson DC Antibiotic prophylaxis of infective endocarditis in the United Kingdom and Europe. 1987 J. Antimicrob. Chemother. pmid:3119557
Feix JB et al. Interactions of 14N:15N stearic acid spin-label pairs: effects of host lipid alkyl chain length and unsaturation. 1987 Biochemistry pmid:2820479
Roughan PG et al. Metabolism of exogenous long-chain fatty acids by spinach leaves. 1987 Arch. Biochem. Biophys. pmid:3426240
Tonnet ML and Green AG Characterization of the seed and leaf lipids of high and low linolenic acid flax genotypes. 1987 Arch. Biochem. Biophys. pmid:3813554
Ong DE et al. Acyl-CoA-independent esterification of retinol bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine. 1987 J. Biol. Chem. pmid:3818619
Berlin E et al. Influence of saturated and unsaturated fats on platelet fatty acids in cholesterol-fed rabbits. 1987 Atherosclerosis pmid:3827974
Albertini G et al. Studies of structural modifications induced by gamma-irradiation in distearoylphosphatidylcholine liposomes. 1987 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:3496306
Carter BL et al. Gastrointestinal side effects with erythromycin preparations. 1987 Drug Intell Clin Pharm pmid:3498618
Seifert R et al. Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. 1987 Biochem. Biophys. Res. Commun. pmid:3426598
Bos CE et al. Native starch in tablet formulations: properties on compaction. 1987 Pharm Weekbl Sci pmid:3432037
Nadai M et al. [Correlation between in vitro dissolution characteristics of macrolide antibiotic tablets and bioavailability in man]. 1987 Yakugaku Zasshi pmid:3437396
Hasin Y et al. Dietary lipid intake and myocardial electrophysiology. 1987 Isr. J. Med. Sci. pmid:3440741
Cutler RR et al. The effect of polyoxyethylene stearate (POES) on the growth of mycobacteria in radiometric 7H12 Middlebrook TB medium. 1987 Tubercle pmid:3448797
Matsui MS and Jeffrey AM Fatty acid modification of C3H 10T 1/2 fibroblast cells: changes in benzo(a)pyrene metabolism and phorbol ester binding. 1987 Cancer Res. pmid:3471326
Masuzawa Y et al. Distribution of dietary trans-octadecenoate among acyl-CoA and other lipid fractions of rat liver and heart. 1987 Biochim. Biophys. Acta pmid:3593750
Kolesnick RN and Paley AE 1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action. 1987 J. Biol. Chem. pmid:3597411
Habib NA et al. Increased erythrocyte stearic acid desaturation in rats with chemically induced colorectal carcinomas. 1987 Int J Colorectal Dis pmid:3598325
Pyörälä S Effect of some vehicles used in intramammary mastitis preparations on inflammation indicators in milk. 1987 J. Vet. Pharmacol. Ther. pmid:3656512
Emken EA et al. Metabolism in humans of cis-12,trans-15-octadecadienoic acid relative to palmitic, stearic, oleic and linoleic acids. 1987 Lipids pmid:3306237
Dinman BD Aluminum in the lung: the pyropowder conundrum. 1987 J Occup Med pmid:3316541
Hattori T et al. Membrane phospholipid composition and membrane fluidity of human brain tumour: a spin label study. 1987 Neurol. Res. pmid:2883605
Søreide O et al. Inadequacy of oleic acid in erythrocytes as a marker of malignancies. 1987 Br Med J (Clin Res Ed) pmid:3103770
McCormack WM et al. Effect on birth weight of erythromycin treatment of pregnant women. 1987 Obstet Gynecol pmid:3543767