stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Insulinoma D007340 28 associated lipids
Ischemia D007511 18 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Leprosy D007918 8 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Liver Neoplasms D008113 8 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Pohl J et al. Uptake of long-chain fatty acids in HepG2 cells involves caveolae: analysis of a novel pathway. 2002 J. Lipid Res. pmid:12235170
Li S et al. Effect of formulation variables on the floating properties of gastric floating drug delivery system. 2002 Drug Dev Ind Pharm pmid:12236064
Rahmouni M et al. Influence of physical parameters and lubricants on the compaction properties of granulated and non-granulated cross-linked high amylose starch. 2002 Chem. Pharm. Bull. pmid:12237529
Shimono N et al. Design of controlled release system with multi-layers of powder. 2002 Chem. Pharm. Bull. pmid:12237531
Gu W et al. [Chemical composition of Fordia cauliflora Hemsl]. 1999 Zhongguo Zhong Yao Za Zhi pmid:12242814
Arici M et al. Fatty acids carried on albumin modulate proximal tubular cell fibronectin production: a role for protein kinase C. 2002 Nephrol. Dial. Transplant. pmid:12270980
Tola S Occupational lead exposure in Finland. IV. The polyvinyl chloride plastic industry. 1975 Scand J Work Environ Health pmid:1228897
Vicentino C et al. Long-chain fatty acid uptake and oxidation in the perfused liver of Walker-256 tumour-bearing rats. 2002 Liver pmid:12296968
Ahmed M and Enever RP Influence of magnesium stearate on the dissolution and biological availability of sulphadiazine tablet formulations [proceedings]. 1976 J. Pharm. Pharmacol. pmid:12326
Kopp F et al. Instability of Langmuir-Blodgett layers of barium stearate, cadmium arachidate and tripalmitin, studied by means of electron microscopy and infrared spectroscopy. 1975 Biophys. Struct. Mech. pmid:1234025
Gray AP and Guardina WJ Long-acting narcotic antagonist complexes. 1975 Natl Inst Drug Abuse Res Monogr Ser pmid:1234981
Houmard JA et al. Effect of weight loss on insulin sensitivity and intramuscular long-chain fatty acyl-CoAs in morbidly obese subjects. 2002 Diabetes pmid:12351433
Phadke RS Sedimentation test for procaine benzylpenicillin in oil with aluminium monostearate. III. Substitution of the sedimentation rate for the blood-level duration test of WHO in rabbits. 1975 Aug-Nov Hindustan Antibiot Bull pmid:1236093
Cowles RL et al. Dietary stearic acid alters gallbladder bile acid composition in hamsters fed cereal-based diets. 2002 J. Nutr. pmid:12368404
Sudah OS et al. Mixing of cohesive pharmaceutical formulations in tote (bin) blenders. 2002 Drug Dev Ind Pharm pmid:12378960
Okamoto H et al. Development of polymer film dosage forms of lidocaine for buccal administration: II. Comparison of preparation methods. 2002 J Pharm Sci pmid:12379928
Samoylov AM et al. Peptide biosensor for recognition of cross-species cell surface markers. 2002 Jul-Aug J. Mol. Recognit. pmid:12382237
Jandura P et al. Inverse gas chromatography study on partially esterified paper fiber. 2002 J Chromatogr A pmid:12385400
Mougios V et al. Duration of coffee- and exercise-induced changes in the fatty acid profile of human serum. 2003 J. Appl. Physiol. pmid:12391036
Shanker G et al. Methylmercury enhances arachidonic acid release and cytosolic phospholipase A2 expression in primary cultures of neonatal astrocytes. 2002 Brain Res. Mol. Brain Res. pmid:12393259