| MeSH term | MeSH ID | Detail |
|---|---|---|
| Insulinoma | D007340 | 28 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Hypothalamic Diseases | D007027 | 3 associated lipids |
| Hypopituitarism | D007018 | 7 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| De Girolamo J et al. | Layer-by-layer assembled composite films of side-functionalized poly(3-hexylthiophene) and CdSe nanocrystals: electrochemical, spectroelectrochemical and photovoltaic properties. | 2008 | Phys Chem Chem Phys | pmid:18597017 |
| Ikonen M et al. | Controlled complexation of plasmid DNA with cationic polymers: effect of surfactant on the complexation and stability of the complexes. | 2008 | Colloids Surf B Biointerfaces | pmid:18583110 |
| Shah RB et al. | Stability indicating validated HPLC method for quantification of levothyroxine with eight degradation peaks in the presence of excipients. | 2008 | Int J Pharm | pmid:18524511 |
| Liang L and Fang Y | Photoluminescence of a mixed Langmuir-Blodgett film of C(60) and stearic acid at room temperature. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17499018 |
| Whitby CP et al. | Effect of oil soluble surfactant in emulsions stabilised by clay particles. | 2008 | J Colloid Interface Sci | pmid:18452938 |
| He X et al. | Formulation development and process scale up of a high shear wet granulation formulation containing a poorly wettable drug. | 2008 | J Pharm Sci | pmid:18449937 |
| John Wallace R | Gut microbiology - broad genetic diversity, yet specific metabolic niches. | 2008 | Animal | pmid:22443591 |
| Bermúdez L et al. | A candidate gene survey of quantitative trait loci affecting chemical composition in tomato fruit. | 2008 | J. Exp. Bot. | pmid:18552354 |
| Chen Y et al. | Isolation of 5-hydroxypyrrolidin-2-one and other constituents from the young fronds of Pteridium aquilinum. | 2008 | J Nat Med | pmid:18437503 |
| Riegler J et al. | Blue shift of CdSe/ZnS nanocrystal-labels upon DNA-hybridization. | 2008 | J Nanobiotechnology | pmid:18489732 |
| Simon MN et al. | Persistent activation of Akt or ERK prevents the toxicity induced by saturated and polyunsaturated fatty acids in RINm5F β-cells. | 2008 | Toxicol In Vitro | pmid:18395405 |
| Arida AI and Al-Tabakha MM | Cellactose a co-processed excipient: a comparison study. | 2008 | Pharm Dev Technol | pmid:18379907 |
| Ranji A et al. | Determination of calcium stearate in polyolefin samples by gas chromatographic technique after performing dispersive liquid-liquid microextraction. | 2008 | Anal Sci | pmid:18469468 |
| McHedlov-Petrossyan NO et al. | Fluorescent dye N,N'-dioctadecylrhodamine as a new interfacial acid-base indicator. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17681854 |
| Jones PJ | Dietary agents that target gastrointestinal and hepatic handling of bile acids and cholesterol. | 2008 | J Clin Lipidol | pmid:21291720 |
| Shah RB et al. | Comparative evaluation of flow for pharmaceutical powders and granules. | 2008 | AAPS PharmSciTech | pmid:18446489 |
| Lee YH et al. | Separation and determination of polyethylene glycol fatty acid esters in cosmetics by a reversed-phase HPLC/ELSD. | 2008 | Talanta | pmid:18371826 |
| Darole PS et al. | Formulation and evaluation of microemulsion based delivery system for amphotericin B. | 2008 | AAPS PharmSciTech | pmid:18446472 |
| Flasiński M et al. | Per-6-O-(tert-butyldimethylsilyl)cyclodextrins (TBDMS-CDs) in Langmuir monolayers: the importance of a spreading solvent in the preparation of LB layers suitable for sensor application. | 2008 | J Phys Chem B | pmid:18358030 |
| Liao KS et al. | Superhydrophobic surfaces formed using layer-by-layer self-assembly with aminated multiwall carbon nanotubes. | 2008 | Langmuir | pmid:18324860 |
| Fujimoto Y et al. | Stearic acid potently modulates the activity of cyclooxygenase-1, but not cyclooxygenase-2, in the form of its CoA ester. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18083017 |
| Hentschel A et al. | Beta-carotene-loaded nanostructured lipid carriers. | 2008 | J. Food Sci. | pmid:18298743 |
| Salas JJ et al. | The biochemical characterization of a high-stearic acid sunflower mutant reveals the coordinated regulation of stearoyl-acyl carrier protein desaturases. | 2008 | Plant Physiol. Biochem. | pmid:18023195 |
| Georget DM et al. | A study on maize proteins as a potential new tablet excipient. | 2008 | Eur J Pharm Biopharm | pmid:18294824 |
| Lee DY and Fiehn O | High quality metabolomic data for Chlamydomonas reinhardtii. | 2008 | Plant Methods | pmid:18442406 |
| Sun CC | On the mechanism of reduced tabletability of granules prepared by roller compaction. | 2008 | Int J Pharm | pmid:18024020 |
| Gouda AA and Hassan WS | Spectrophotometric determination of etodolac in pure form and pharmaceutical formulations. | 2008 | Chem Cent J | pmid:18410679 |
| Kim CH et al. | Effects of emulsified octadecanic acids on gas production and cellulolysis by the rumen anaerobic fungus, Piromyces communis M014. | 2008 | Anaerobe | pmid:17996466 |
| Hu FQ et al. | Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin. | 2008 | Eur J Pharm Biopharm | pmid:17997293 |
| Jose R et al. | Dependence of luminescence efficiency of cdse quantum dots on chemical environments. | 2008 | J Nanosci Nanotechnol | pmid:19198279 |
| Ebbesson SO et al. | Consumption of omega-3 fatty acids is not associated with a reduction in carotid atherosclerosis: the Genetics of Coronary Artery Disease in Alaska Natives study. | 2008 | Atherosclerosis | pmid:18054937 |
| Widjaja E and Seah RK | Application of Raman microscopy and band-target entropy minimization to identify minor components in model pharmaceutical tablets. | 2008 | J Pharm Biomed Anal | pmid:17980994 |
| Piao ZZ et al. | Colonic release and reduced intestinal tissue damage of coated tablets containing naproxen inclusion complex. | 2008 | Int J Pharm | pmid:17928177 |
| Jones OA et al. | A metabolomics based approach to assessing the toxicity of the polyaromatic hydrocarbon pyrene to the earthworm Lumbricus rubellus. | 2008 | Chemosphere | pmid:17928029 |
| El-Enany N et al. | Spectrofluorimetric determination of oxamniquine in dosage forms and spiked human plasma through derivatization with 1-dimethylaminonaphthalene-5-sulphonyl chloride. | 2008 | J Fluoresc | pmid:18058206 |
| Rhee YS et al. | Application of instrumental evaluation of color for the pre-formulation and formulation of rabeprazole. | 2008 | Int J Pharm | pmid:17919858 |
| Guchardi R et al. | Influence of fine lactose and magnesium stearate on low dose dry powder inhaler formulations. | 2008 | Int J Pharm | pmid:17689898 |
| Vehring R | Pharmaceutical particle engineering via spray drying. | 2008 | Pharm. Res. | pmid:18040761 |
| Wu H et al. | Process analytical technology (PAT): quantification approaches in terahertz spectroscopy for pharmaceutical application. | 2008 | J Pharm Sci | pmid:17722101 |
| Hamad ML et al. | Functionality of magnesium stearate derived from bovine and vegetable sources: dry granulated tablets. | 2008 | J Pharm Sci | pmid:18351597 |
| Guo J et al. | Phenolic molding compound filled with nonmetals of waste PCBs. | 2008 | Environ. Sci. Technol. | pmid:18284173 |
| Nyblom HK et al. | Glucose-induced de novo synthesis of fatty acyls causes proportional increases in INS-1E cellular lipids. | 2008 | NMR Biomed | pmid:17691080 |
| Werle M | Natural and synthetic polymers as inhibitors of drug efflux pumps. | 2008 | Pharm. Res. | pmid:17896100 |
| Moate PJ et al. | Milk fatty acids II: prediction of the production of individual fatty acids in bovine milk. | 2008 | J. Dairy Sci. | pmid:18292274 |
| Almaya A and Aburub A | Effect of particle size on compaction of materials with different deformation mechanisms with and without lubricants. | 2008 | AAPS PharmSciTech | pmid:18431664 |
| Bushra R et al. | Formulation development and optimization of Ibuprofen tablets by direct compression method. | 2008 | Pak J Pharm Sci | pmid:18390440 |
| Kuno Y et al. | Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol. | 2008 | Eur J Pharm Biopharm | pmid:18396020 |
| Kauffman JF et al. | Near infrared spectroscopy of magnesium stearate hydrates and multivariate calibration of pseudopolymorph composition. | 2008 | J Pharm Sci | pmid:17546666 |
| Moore IM et al. | Methotrexate-induced alterations in beta-oxidation correlate with cognitive abilities in children with acute lymphoblastic leukemia. | 2008 | Biol Res Nurs | pmid:18398226 |
| Bacher C et al. | Compressibility and compactibility of granules produced by wet and dry granulation. | 2008 | Int J Pharm | pmid:18407441 |
| Teixeira AC et al. | Phase behaviour of binary mixtures involving tristearin, stearyl stearate and stearic acid: thermodynamic study and BAM observation at the air-water interface and AFM analysis of LB films. | 2008 | Chem. Phys. Lipids | pmid:18407835 |
| Gmucová K et al. | Orientation ordering of nanoparticle Ag/Co cores controlled by electric and magnetic fields. | 2008 | Chemphyschem | pmid:18386264 |
| Crowe FL et al. | Fatty acid composition of plasma phospholipids and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition. | 2008 | Am. J. Clin. Nutr. | pmid:18996872 |
| Isaev NP and Dzuba SA | Fast stochastic librations and slow rotations of spin labeled stearic acids in a model phospholipid bilayer at cryogenic temperatures. | 2008 | J Phys Chem B | pmid:18826269 |
| Koseki T et al. | Development of novel fast-disintegrating tablets by direct compression using sucrose stearic acid ester as a disintegration-accelerating agent. | 2008 | Chem. Pharm. Bull. | pmid:18827375 |
| Navarro-Tarazaga ML et al. | Fatty acid effect on hydroxypropyl methylcellulose-beeswax edible film properties and postharvest quality of coated 'Ortanique' mandarins. | 2008 | J. Agric. Food Chem. | pmid:18950188 |
| Dillon R et al. | Development of a novel LC/MS method to quantitate cellular stearoyl-CoA desaturase activity. | 2008 | Anal. Chim. Acta | pmid:18790132 |
| Abbasi M et al. | Further investigation of lipid-substituted poly(L-Lysine) polymers for transfection of human skin fibroblasts. | 2008 | Biomacromolecules | pmid:18498191 |
| Pi K et al. | [Study on liposoluble constituents of Teucrium labiosum]. | 2008 | Zhong Yao Cai | pmid:18973016 |
| Hernández ML et al. | The utilization and desaturation of oleate and linoleate during glycerolipid biosynthesis in olive (Olea europaea L.) callus cultures. | 2008 | J. Exp. Bot. | pmid:18515829 |
| Fang YP et al. | Physicochemical and safety evaluation of 5-aminolevulinic acid in novel liposomes as carrier for skin delivery. | 2008 | J Liposome Res | pmid:18348070 |
| Lasserre R et al. | Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation. | 2008 | Nat. Chem. Biol. | pmid:18641634 |
| Zhang JX et al. | Sex- and gonad-affecting scent compounds and 3 male pheromones in the rat. | 2008 | Chem. Senses | pmid:18515819 |
| Lockridge JB et al. | Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. | 2008 | J. Lipid Res. | pmid:18387886 |
| Sadhu HG et al. | Poisoning of workers working in small lead-based units. | 2008 | Indian J Occup Environ Med | pmid:20040974 |
| Kirtsreesakul V et al. | Microbiology and antimicrobial susceptibility patterns of commensal flora in the middle nasal meatus. | 2008 | Ann. Otol. Rhinol. Laryngol. | pmid:19140538 |
| Ellison CD et al. | Measuring the distribution of density and tabletting force in pharmaceutical tablets by chemical imaging. | 2008 | J Pharm Biomed Anal | pmid:18539424 |
| Fernández EG et al. | Rapid development and optimization of tablet manufacturing using statistical tools. | 2008 | AAPS PharmSciTech | pmid:18459048 |
| Chang CK et al. | Roller compaction, granulation and capsule product dissolution of drug formulations containing a lactose or mannitol filler, starch, and talc. | 2008 | AAPS PharmSciTech | pmid:18459052 |
| Zeng Q et al. | Highly luminescent CdSe/ZnSe core-shell quantum dots of one-pot preparation in octadecene. | 2008 | J Nanosci Nanotechnol | pmid:18468151 |
| Kordyukova LV et al. | S acylation of the hemagglutinin of influenza viruses: mass spectrometry reveals site-specific attachment of stearic acid to a transmembrane cysteine. | 2008 | J. Virol. | pmid:18596092 |
| Asadi A et al. | Interaction of bovine serum albumin with some novel PEG-containing diblock copolymers. | 2008 | Int. J. Biol. Macromol. | pmid:18602419 |
| Richardson AD et al. | Central carbon metabolism in the progression of mammary carcinoma. | 2008 | Breast Cancer Res. Treat. | pmid:17879159 |
| Smirnov AI | Post-processing of EPR spectra by convolution filtering: calculation of a harmonics' series and automatic separation of fast-motion components from spin-label EPR spectra. | 2008 | J. Magn. Reson. | pmid:17967556 |
| Liu C et al. | In situ intestinal absorption of cyclosporine A solid dispersion in rats. | 2008 | Drug Dev Ind Pharm | pmid:18568913 |
| Lumor SE et al. | Optimization of solid fat content and crystal properties of a trans-free structured lipid by blending with palm midfraction. | 2008 | J. Agric. Food Chem. | pmid:18781758 |
| Moon CD et al. | Reclassification of Clostridium proteoclasticum as Butyrivibrio proteoclasticus comb. nov., a butyrate-producing ruminal bacterium. | 2008 | Int. J. Syst. Evol. Microbiol. | pmid:18768601 |
| Terés S et al. | Oleic acid content is responsible for the reduction in blood pressure induced by olive oil. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18772370 |
| Weber D et al. | Quantification of lubricant activity of magnesium stearate by atomic force microscopy. | 2008 | Drug Dev Ind Pharm | pmid:18777241 |
| Simonsick WJ and Petkovska VI | Detailed structural elucidation of polyesters and acrylates using Fourier transform mass spectrometry. | 2008 | Anal Bioanal Chem | pmid:18719895 |
| Almeida IF et al. | Moisturizing effect of oleogel/hydrogel mixtures. | 2008 | Pharm Dev Technol | pmid:18720247 |
| Badillo N and Ghaly ES | In vitro evaluation of theophylline matrices using xyloglucan. | 2008 | Pharm Dev Technol | pmid:18720251 |
| Ling XY et al. | Supramolecular layer-by-layer assembly of 3D multicomponent nanostructures via multivalent molecular recognition. | 2008 | Int J Mol Sci | pmid:19325764 |
| Tolson J et al. | A green humidifier chamber. | 2008 | Eur. Respir. J. | pmid:18669801 |
| Bigucci F et al. | Chitosan salts coated with stearic acid as colon-specific delivery systems for vancomycin. | 2008 | Drug Deliv | pmid:18763159 |
| Ye YQ et al. | Core-modified chitosan-based polymeric micelles for controlled release of doxorubicin. | 2008 | Int J Pharm | pmid:18096336 |
| Aleong JM et al. | Ice recrystallization inhibition in ice cream by propylene glycol monostearate. | 2008 | J. Food Sci. | pmid:19021802 |
| Johansson TP and Leach GW | A low temperature phase transition in Langmuir-Blodgett films. | 2008 | J Phys Chem B | pmid:18855435 |
| Mazumder B et al. | Flow of Formulation Granules through a Conical Hopper. | 2008 | Indian J Pharm Sci | pmid:21369452 |
| Shah DA et al. | Stability Indicating RP-HPLC Estimation of Atorvastatin Calcium and Amlodipine Besylate in Pharmaceutical Formulations. | 2008 | Indian J Pharm Sci | pmid:21369436 |
| Zhang XX et al. | Effects of breast cancer resistance protein inhibitors and pharmaceutical excipients on decreasing gastrointestinal toxicity of camptothecin analogs. | 2008 | Acta Pharmacol. Sin. | pmid:18954535 |
| Teixeira AC et al. | Microdomains in mixed monolayers of oleanolic and stearic acids: thermodynamic study and BAM observation at the air-water interface and AFM and FTIR analysis of LB monolayers. | 2007 Sep-Oct | Chem. Phys. Lipids | pmid:17583687 |
| Naidu KA et al. | P53 enhances ascorbyl stearate-induced G2/M arrest of human ovarian cancer cells. | 2007 Nov-Dec | Anticancer Res. | pmid:18225552 |
| Lumor SE et al. | Synthesis and characterization of canola oil-stearic acid-based trans-free structured lipids for possible margarine application. | 2007 | J. Agric. Food Chem. | pmid:18052237 |
| Barman S and Vasudevan S | Mixed saturated-unsaturated alkyl-chain assemblies: solid solutions of zinc stearate and zinc oleate. | 2007 | J Phys Chem B | pmid:17441755 |
| Chung DJ et al. | Black cohosh and St. John's wort (GYNO-Plus) for climacteric symptoms. | 2007 | Yonsei Med. J. | pmid:17461529 |
| Crunkhorn S et al. | Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. | 2007 | J. Biol. Chem. | pmid:17416903 |
| Grice DE et al. | Transcriptional profiling of C57 and DBA strains of mice in the absence and presence of morphine. | 2007 | BMC Genomics | pmid:17367521 |
| Pagliassotti MJ et al. | Insulin protects liver cells from saturated fatty acid-induced apoptosis via inhibition of c-Jun NH2 terminal kinase activity. | 2007 | Endocrinology | pmid:17431009 |
| Bacher C et al. | Improving the compaction properties of roller compacted calcium carbonate. | 2007 | Int J Pharm | pmid:17582712 |