MeSH term | MeSH ID | Detail |
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Body Weight | D001835 | 333 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Lee I and Kadenbach B | Palmitate decreases proton pumping of liver-type cytochrome c oxidase. | 2001 | Eur. J. Biochem. | pmid:11737187 |
Kuppuswamy R et al. | Estimation of capping incidence by indentation fracture tests. | 2001 | AAPS PharmSci | pmid:11741256 |
Otsuka M et al. | Comparative evaluation of tableting compression behaviors by methods of internal and external lubricant addition: inhibition of enzymatic activity of trypsin preparation by using external lubricant addition during the tableting compression process. | 2001 | AAPS PharmSci | pmid:11741271 |
Mackin L et al. | The impact of low levels of amorphous material (<5%) on the blending characteristics of a direct compression formulation. | 2002 | Int J Pharm | pmid:11755273 |
Comai K et al. | Analyses of renal medullary lipid droplets from normal, hydronephrotic, and indomethacin treated rabbits. | 1975 | Lipids | pmid:1177669 |
Jensen RG et al. | Parenteral infusion of a lactating woman with intralipid: changes in milk and plasma fatty acids. | 2001 | Adv. Exp. Med. Biol. | pmid:11787679 |
Yu MD et al. | The effect of formulation on reduced radioiodide thyroid uptake. | 2002 | J. Nucl. Med. | pmid:11801703 |
Pedrazzi V et al. | Tensile bond strength of a polymeric intra-buccal bioadhesive: the mucin role. | 2001 Nov-Dec | Boll Chim Farm | pmid:11822242 |
Papanikolaou S et al. | Kinetic profile of the cellular lipid composition in an oleaginous Yarrowia lipolytica capable of producing a cocoa-butter substitute from industrial fats. | 2001 | Antonie Van Leeuwenhoek | pmid:11827207 |
Bassilian S et al. | Loss of regulation of lipogenesis in the Zucker diabetic rat. II. Changes in stearate and oleate synthesis. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11832351 |