stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hypothyroidism D007037 32 associated lipids
Burns D002056 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Acne Vulgaris D000152 35 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Adenoma D000236 40 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Occupational Diseases D009784 42 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Bergquist SO et al. Erythromycin in the treatment of pertussis: a study of bacteriologic and clinical effects. 1987 Pediatr. Infect. Dis. J. pmid:2885802
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West AA et al. The relationship between glycosyltransferase production and membrane fatty acid composition of Streptococcus sanguis NCTC 7865 grown in the presence of protonmotive force inhibitors. 1987 J. Gen. Microbiol. pmid:2966234
Ondrias K et al. Spin label study of the perturbation effect of the local anaesthetics tetracaine and dibucaine on synaptosomes at pharmacological concentrations. 1987 Biochem. Pharmacol. pmid:2825709
Reddy TS and Bazan NG Arachidonic acid, stearic acid, and diacylglycerol accumulation correlates with the loss of phosphatidylinositol 4,5-bisphosphate in cerebrum 2 seconds after electroconvulsive shock: complete reversion of changes 5 minutes after stimulation. 1987 J. Neurosci. Res. pmid:2830409
Ogata S et al. Chemical identification of lipid components in the membranous form of rat liver alkaline phosphatase. 1987 J. Biochem. pmid:2834351
Swendsen CL et al. Human neutrophils incorporate arachidonic acid and saturated fatty acids into separate molecular species of phospholipids. 1987 Biochim. Biophys. Acta pmid:3105590
DeGeorge JJ et al. Acetylcholine stimulates selective liberation and re-esterification of arachidonate and accumulation of inositol phosphates and glycerophosphoinositol in C62B glioma cells. 1987 J. Biol. Chem. pmid:3110145
Morse DR et al. Infectious flare-ups and serious sequelae following endodontic treatment: a prospective randomized trial on efficacy of antibiotic prophylaxis in cases of asymptomatic pulpal-periapical lesions. 1987 Oral Surg. Oral Med. Oral Pathol. pmid:3112672
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Halát G et al. Effects of incomplete ischemia and subsequent recirculation on free palmitate, stearate, oleate and arachidonate levels in lumbar and cervical spinal cord of rabbit. 1987 Gen. Physiol. Biophys. pmid:3117617
Imai A and Gershengorn MC Measurement of lipid turnover in response to thyrotropin-releasing hormone. 1987 Meth. Enzymol. pmid:3037241
Roughan PG et al. Metabolism of exogenous long-chain fatty acids by spinach leaves. 1987 Arch. Biochem. Biophys. pmid:3426240
Habib NA et al. Stearic acid and carcinogenesis. 1987 Br. J. Cancer pmid:3689663
Rhoads DE et al. Metabolism of saturated fatty acids by Paramecium tetraurelia. 1987 J. Lipid Res. pmid:3430068
Kaya K and Nohara K Effect of di-n-octyl phthalate on fatty acid composition of phosphatidylcholine in Tetrahymena. 1987 Chem. Biol. Interact. pmid:3690725
Ong DE et al. Acyl-CoA-independent esterification of retinol bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine. 1987 J. Biol. Chem. pmid:3818619
Berlin E et al. Influence of saturated and unsaturated fats on platelet fatty acids in cholesterol-fed rabbits. 1987 Atherosclerosis pmid:3827974
Carter BL et al. Gastrointestinal side effects with erythromycin preparations. 1987 Drug Intell Clin Pharm pmid:3498618
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Hasin Y et al. Dietary lipid intake and myocardial electrophysiology. 1987 Isr. J. Med. Sci. pmid:3440741
Cutler RR et al. The effect of polyoxyethylene stearate (POES) on the growth of mycobacteria in radiometric 7H12 Middlebrook TB medium. 1987 Tubercle pmid:3448797
Matsui MS and Jeffrey AM Fatty acid modification of C3H 10T 1/2 fibroblast cells: changes in benzo(a)pyrene metabolism and phorbol ester binding. 1987 Cancer Res. pmid:3471326
Habib NA et al. Desaturation-producing factor present in the tissue, blood, and urine of cancer patients. 1987 Cancer Detect. Prev. pmid:3568009
Wang ST et al. A comparison of fatty acid composition of cholesteryl esters in subjects at various concentrations of serum lipid. 1987 Clin. Biochem. pmid:3568345
Pospísilová B and Kubes J [Stability of erythromycin stearate in coated tablets during the action of gastric juice in vitro]. 1987 Cesk Farm pmid:3581192
Worman CP et al. Saturation index of blood cell membrane fatty acids before and after IFN treatment in hairy cell leukemia. 1987 Leukemia pmid:3669764
Caglayan S et al. Is medical therapy effective for regional lymphadenitis following BCG vaccination? 1987 Am. J. Dis. Child. pmid:3673975
Venho VM et al. The value of comparative bioavailability studies of marketed drugs in drug control. An example with erythromycin stearate. 1987 Methods Find Exp Clin Pharmacol pmid:3683018
Bridges CD et al. Rhodopsin, vitamin A, and interstitial retinol-binding protein in the rd chicken. 1987 Invest. Ophthalmol. Vis. Sci. pmid:3557867
Hope MJ and Cullis PR Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. 1987 J. Biol. Chem. pmid:3558410
Husebye ES and Flatmark T Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. 1987 Biochim. Biophys. Acta pmid:3607074
Cavalleri A and Minoia C Lead level of whole blood and plasma in workers exposed to lead stearate. 1987 Scand J Work Environ Health pmid:3616550
Seimiya T et al. Effects of composition and molecular packing on ionic properties of lipid monolayer having both cationic and anionic head groups. 1987 Chem. Phys. Lipids pmid:3621383
Salminen S and Salminen E Urinary excretion of orally administered oxalic acid in MYRJ 45-treated NMRI mice. 1987 Toxicol. Lett. pmid:3590233
Dinman BD Aluminum in the lung: the pyropowder conundrum. 1987 J Occup Med pmid:3316541
Hattori T et al. Membrane phospholipid composition and membrane fluidity of human brain tumour: a spin label study. 1987 Neurol. Res. pmid:2883605
Søreide O et al. Inadequacy of oleic acid in erythrocytes as a marker of malignancies. 1987 Br Med J (Clin Res Ed) pmid:3103770
McCormack WM et al. Effect on birth weight of erythromycin treatment of pregnant women. 1987 Obstet Gynecol pmid:3543767
Kringsholm B and Christoffersen P The nature and the occurrence of birefringent material in different organs in fatal drug addiction. 1987 May-Jun Forensic Sci. Int. pmid:3036675
Udod VM et al. [Microbial breakdown of stearox-6 and a study of the genetic determination of the nature of the degradative activity]. 1987 May-Jun Mikrobiol. Zh. pmid:3150493
Shani J et al. Efficacy of sustained-release radioprotective drugs in vivo. 1987 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:2966504
Loscalzo J et al. Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells. 1987 Sep-Oct Arteriosclerosis pmid:3675304
Takenaka T et al. Effects of arachidonic acid and the other long-chain fatty acids on the membrane currents in the squid giant axon. 1988 J. Membr. Biol. pmid:3147335
Sanjurjo P et al. Plasma fatty acid composition during the first week of life following feeding with human milk or formula. 1988 Acta Paediatr Scand pmid:3354331
Graham A et al. Fatty acid specificity for the synthesis of triacylglycerol and phosphatidylcholine and for the secretion of very-low-density lipoproteins and lysophosphatidylcholine by cultures of rat hepatocytes. 1988 Biochem. J. pmid:3355493
Bonanome A and Grundy SM Effect of dietary stearic acid on plasma cholesterol and lipoprotein levels. 1988 N. Engl. J. Med. pmid:3362176
Sparace SA et al. A preliminary analysis of Fatty Acid synthesis in pea roots. 1988 Plant Physiol. pmid:16666088