stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Lymphadenitis D008199 8 associated lipids
Lymphoma D008223 18 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Melanoma D008545 69 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Neuroblastoma D009447 66 associated lipids
Occupational Diseases D009784 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Marchut E et al. The inhibitory effect of various fatty acids on aerobic glycolysis in Ehrlich ascites tumour cells. 1986 Acta Biochim. Pol. pmid:2940781
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Smith DM and Waite M Phospholipid metabolism in human neutrophil subfractions. 1986 Arch. Biochem. Biophys. pmid:3083776
Singh H and Poulos A A comparative study of stearic and lignoceric acid oxidation by human skin fibroblasts. 1986 Arch. Biochem. Biophys. pmid:3767370
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Esezobo S The effect of some excipients on the physical properties of a paracetamol tablet formulation. 1985 J. Pharm. Pharmacol. pmid:2858567
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Yasuda H et al. Biphasic liberation of arachidonic and stearic acids during cerebral ischemia. 1985 J. Neurochem. pmid:2987409
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Shanson DC et al. Erythromycin stearate, 1.5 g, for the oral prophylaxis of streptococcal bacteraemia in patients undergoing dental extraction: efficacy and tolerance. 1985 J. Antimicrob. Chemother. pmid:3882657
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Bertrand G et al. [The value of polyglactin 910 combined with a resorbable bone wax for filling periodontal bone defects]. 1985 Actual Odontostomatol (Paris) pmid:2425560
Wadström T et al. Hydrophobized wound dressing in the treatment of experimental Staphylococcus aureus infections in the young pig. 1985 Acta Pathol Microbiol Immunol Scand B pmid:2417448
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Harrison GA et al. Resistance in oral streptococci after repeated three-dose erythromycin prophylaxis. 1985 J. Antimicrob. Chemother. pmid:4008379
Roblot L et al. Effect of lubricant level and applied compressional pressure on surface friction of tablets. 1985 J Pharm Sci pmid:4020661
Fujii M et al. Fatty acid compositions of triacylglycerols and phospholipids in hen liver lipid before and after sexual maturity. 1985 Poult. Sci. pmid:4022907
Carranco E et al. Carbamazepine toxicity induced by concurrent erythromycin therapy. 1985 Arch. Neurol. pmid:3977647
Ruwart MJ et al. 16,16-Dimethyl PGE2 and fatty acids protect hepatocytes against CCl4-induced damage. 1985 In Vitro Cell. Dev. Biol. pmid:4030626
Sklan D et al. Digestion and absorption of lipids and bile acids in sheep fed stearic acid, oleic acid, or tristearin. 1985 J. Dairy Sci. pmid:4031186
Bridges CD et al. Vitamin A and interstitial retinol-binding protein in an eye with recessive retinitis pigmentosa. 1985 Invest. Ophthalmol. Vis. Sci. pmid:4039711
Beckurts TE et al. Kinetics of different 123I- and 14C-labelled fatty acids in normal and diabetic rat myocardium in vivo. 1985 Nucl Med Commun pmid:4047532
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Griffiths G et al. The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. 1985 Biochem. J. pmid:4052051