stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Lymphadenitis D008199 8 associated lipids
Lymphoma D008223 18 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Melanoma D008545 69 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Neuroblastoma D009447 66 associated lipids
Occupational Diseases D009784 42 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Canonico PL et al. Arachidonate stimulates prolactin release in vitro: a role for the fatty acid and its metabolites as intracellular regulator(s) in mammotrophs. 1985 Endocrinology pmid:2981065
Politi LE et al. Dexamethasone effect on free fatty acid and diacylglycerol accumulation during experimentally induced vasogenic brain edema. 1985 Neurochem Pathol pmid:3831846
Johansson ME Investigations of the mixing time dependence of the lubricating properties of granular and powdered magnesium stearate. 1985 Acta Pharm. Suec. pmid:3832785
Goto S et al. [Effect of magnesium stearate in preparation of eudragit RS-microcapsules containing drugs]. 1985 Yakugaku Zasshi pmid:3835255
Apostolov K et al. Reduction in the stearic to oleic acid ratio in leukaemic cells--a possible chemical marker of malignancy. 1985 Blut pmid:3859340
Boiron F et al. A comparison of substrate-dependent fatty acyl-CoA synthetase activities and ATP hydrolysis in membrane pellets from normal and trembler mouse sciatic nerves. 1985 Neurochem. Int. pmid:20492990
Rendu F et al. Platelet membrane molecular organization: relationship with membrane bound calcium. 1985 Biochem. Biophys. Res. Commun. pmid:2983699
Habenicht AJ et al. Cell cycle-dependent changes in arachidonic acid and glycerol metabolism in Swiss 3T3 cells stimulated by platelet-derived growth factor. 1985 J. Biol. Chem. pmid:3918038
Noble RC and Shand JH Unsaturated fatty acid compositional changes and desaturation during the embryonic development of the chicken (Gallus domesticus). 1985 Lipids pmid:3925271
Wood CB et al. Increase of oleic acid in erythrocytes associated with malignancies. 1985 Br Med J (Clin Res Ed) pmid:3926106
George M and Chepenik KP Phospholipase A activities in embryonic palate mesenchyme cells in vitro. 1985 Biochim. Biophys. Acta pmid:3927980
Galey CI et al. Modulation of phospholipid metabolism in murine keratinocytes by tumor promoter, 12-O-tetradecanoylphorbol-13-acetate. 1985 J. Invest. Dermatol. pmid:3930615
Jones PJ et al. Whole body oxidation of dietary fatty acids: implications for energy utilization. 1985 Am. J. Clin. Nutr. pmid:3933323
Kaplan E and Ansari K High-performance liquid chromatography as a tool for identification of linolenic acid hydroperoxide prepared with soybean lipoxygenase. 1985 J. Chromatogr. pmid:3937844
Maiti H and Haye KR Does detection of chlamydial antibodies by microimmunofluorescence help in managing chlamydial lower genital tract infection in women? 1985 Genitourin Med pmid:3891584
Griffiths G et al. The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. 1985 Biochem. J. pmid:4052051
Stubbs C et al. Determination of erythromycin in serum and urine by high-performance liquid chromatography with ultraviolet detection. 1985 J Pharm Sci pmid:4078714
Baker RR and Loh ZD The subcellular distribution of free fatty acids released during post-decapitative ischemia in rat cerebral cortex. 1985 Can. J. Biochem. Cell Biol. pmid:4084856
Hegde RP et al. Studies of powder flow using a recording powder flowmeter and measurement of the dynamic angle of repose. 1985 J Pharm Sci pmid:3981409
Tse AG et al. A glycophospholipid tail at the carboxyl terminus of the Thy-1 glycoprotein of neurons and thymocytes. 1985 Science pmid:2865810
Crutchley DJ Hydroxyeicosatetraenoic acids and other unsaturated fatty acids inhibit endotoxin-induced thromboplastin activity in human monocytes. 1985 Biochem. Biophys. Res. Commun. pmid:2865954
Johansson ME Influence of the granulation technique and starting material properties on the lubricating effect of granular magnesium stearate. 1985 J. Pharm. Pharmacol. pmid:2867134
Staniforth JN Relationship between particle packing and the physical stability of powder mixes. 1985 J. Pharm. Pharmacol. pmid:2867136
Schreiner A and Digranes A Absorption of erythromycin stearate and enteric-coated erythromycin base after a single oral dose immediately before breakfast. 1984 Sep-Oct Infection pmid:6511088
Blackett PR et al. Hyperlipidemia in acute lymphoblastic leukemia. 1984 Mar-Apr Ann. Clin. Lab. Sci. pmid:6585175
Hanna GM Nuclear magnetic resonance spectroscopic determination of dicyclomine hydrochloride in tablet, capsule, and injection dosage forms. 1984 Mar-Apr J Assoc Off Anal Chem pmid:6725188
Holub BJ and Celi B Evaluation of the fatty acid selectivity of a phosphatidylinositol-specific cytosolic phospholipase C from pig and human platelets. 1984 Feb-Mar Can. J. Biochem. Cell Biol. pmid:6518412
Ras GJ et al. Chemoprophylaxis with erythromycin stearate or amoxycillin in patients with chronic bronchitis--effects on cellular and humoral immune functions. 1984 Dec 22-29 S. Afr. Med. J. pmid:6515508
Foudin L et al. Ethanol consumption and serum lipid profiles in Sinclair(S-1) miniature swine. 1984 Life Sci. pmid:6700380
Sakaguchi M et al. Effect of dietary unsaturated and saturated fats on azoxymethane-induced colon carcinogenesis in rats. 1984 Cancer Res. pmid:6704963
Kemp P et al. The hydrogenation of some cis- and trans-octadecenoic acids to stearic acid by a rumen Fusocillus sp. 1984 Br. J. Nutr. pmid:6743636
Greenberg DS et al. Fatty acid composition of lizard tissue lipids and the effects of estradiol on serum free fatty acids. 1984 Comp. Biochem. Physiol., B pmid:6744817
Walstad RA and Hellum KB Penetration of erythromycin in respiratory tract infections. 1984 Acta Otolaryngol Suppl pmid:6333775
Shanson DC et al. The pharmacokinetics and tolerance of oral erythromycin stearate compared with erythromycin ethylsuccinate: implications for preventing endocarditis. 1984 J. Antimicrob. Chemother. pmid:6334070
Tjandramaga TB et al. Relative bioavailability of enteric coated pellets, stearate and ethylsuccinate formulations of erythromycin. 1984 Pharmacology pmid:6334320
Aylsworth CF et al. Promotion of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis by high dietary fat in the rat: possible role of intercellular communication. 1984 J. Natl. Cancer Inst. pmid:6422115
Kido H et al. Inhibition of chymase activity by long chain fatty acids. 1984 Arch. Biochem. Biophys. pmid:6424574
Lem NW and Stumpf PK In Vitro Fatty Acid Synthesis and Complex Lipid Metabolism in the Cyanobacterium, Anabaena Variabilis: II. Acyl Transfer and Complex Lipid Formation. 1984 Plant Physiol. pmid:16663690
Francis H et al. Severe vascular spasm due to erythromycin-ergotamine interaction. 1984 Clin. Rheumatol. pmid:6236021
Bhakoo KK et al. Regional studies of changes in brain fatty acids following experimental ischaemia and reperfusion in the gerbil. 1984 J. Neurochem. pmid:6236282
Abumrad NA et al. Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. 1984 J. Biol. Chem. pmid:6746632
Rosén C et al. Acute otitis media in older children and adults treated with penicillin or erythromycin. 1984 Acta Otolaryngol Suppl pmid:6437133
Dixon JF and Hokin LE Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase. 1984 J. Biol. Chem. pmid:6438097
Forsberg NE et al. Roles of acetate and its interactions with glucose and lactate in cow mammary tissue. 1984 J. Dairy Sci. pmid:6438200
Desudchit P et al. Rifampicin-erythromycin combination for the treatment of gonococcal urethritis in men. 1984 Southeast Asian J. Trop. Med. Public Health pmid:6441265
Bridges CD et al. Visual cycle in the mammalian eye. Retinoid-binding proteins and the distribution of 11-cis retinoids. 1984 Vision Res. pmid:6543481
Fenyvest E et al. Cyclodextrin polymer, a new tablet disintegrating agent. 1984 Pharmazie pmid:6494226
Junginger H [The ratio of free and fixed interlamellar water as quality criteria for O/W creams]. 1984 Pharmazie pmid:6504995
Kennett FF et al. Inhibition of myocardial rotenone-insensitive NADH cytochrome c reductase by amphiphilic compounds. 1984 Am. J. Physiol. pmid:6507637
Wirthensohn G et al. Phospholipid metabolism in rat kidney cortical tubules. I. Effect of renal substrates. 1984 Biochim. Biophys. Acta pmid:6477951