stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Urticaria D014581 13 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Adenoma D000236 40 associated lipids
Leprosy D007918 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Tremor D014202 15 associated lipids
Lymphadenitis D008199 8 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Higashi N and Senoo H Distribution of vitamin A-storing lipid droplets in hepatic stellate cells in liver lobules--a comparative study. 2003 Anat Rec A Discov Mol Cell Evol Biol pmid:12552640
Tavilani H et al. Decreased polyunsaturated and increased saturated fatty acid concentration in spermatozoa from asthenozoospermic males as compared with normozoospermic males. 2006 Andrologia pmid:16961570
Díaz R et al. Identification of fatty acids in canine seminal plasma. 2014 Andrologia pmid:23398451
Fameau AL et al. Smart foams: switching reversibly between ultrastable and unstable foams. 2011 Angew. Chem. Int. Ed. Engl. pmid:21780260
McNamara S et al. Effect of offering rumen-protected fat supplements on fertility and performance in spring-calving Holstein-Friesian cows. 2003 Anim. Reprod. Sci. pmid:12853178
Vanholder T et al. Effect of non-esterified fatty acids on bovine granulosa cell steroidogenesis and proliferation in vitro. 2005 Anim. Reprod. Sci. pmid:15885439
Vanholder T et al. Effect of non-esterified fatty acids on bovine theca cell steroidogenesis and proliferation in vitro. 2006 Anim. Reprod. Sci. pmid:15978752
Okada K et al. Effect of fatty acids added to the milk replacer on white scour and excretion of fatty acids in Holstein calves. 2009 Anim. Sci. J. pmid:20163618
John Wallace R Gut microbiology - broad genetic diversity, yet specific metabolic niches. 2008 Animal pmid:22443591
CHAKRAVORTI KP and SADHU DP STUDIES ON CHEMICAL COMPOSITION OF PROTEIN AND FAT IN THE OVIDUCT OF THE PIGEON, COLUMBA LIVIA GMELIN. 1963 Ann Biochem Exp Med pmid:14082710
Kohn MC and Garfinkel D Computer simulation of metabolism in palmitate-perfused rat heart. I. Palmitate oxidation. 1983 Ann Biomed Eng pmid:6592996
LAMBIOTTE M [USE OF RADIOACTIVE CHOLESTEROL IN THE STUDY OF THE INFLUENCE OF DIETARY LIPIDS ON CHOLESTEROL METABOLISM]. 1963 Ann Nutr Aliment pmid:14048747
Brouwer DH et al. Size selective dustiness and exposure; simulated workplace comparisons. 2006 Ann Occup Hyg pmid:16524926
Benziane H et al. [Formulation and stability of hospital preparation of 3,4-diaminopyridine capsules]. 2003 Ann Pharm Fr pmid:14639194
Sattar SP et al. Inert medication ingredients causing nonadherence due to religious beliefs. 2004 Ann Pharmacother pmid:14766995
KIVITS M [Frambesia therapy with oil procaine-penicillin with aluminium stearate]. 1951 Ann Soc Belg Med Trop (1920) pmid:14838448
Warhurst DC et al. The blood schizontocidal action of erythromycin against Plasmodium knowlesi infections in Macaca mulatta. 1983 Ann Trop Med Parasitol pmid:6625724
Warhurst DC et al. The chemotherapy of rodent malaria, XXIV. The blood schizontocidal action of erythromycin upon Plasmodium berghei. 1976 Ann Trop Med Parasitol pmid:788656
Królikowska-Prasał I and Zakrzewska-Grzycka T Histochemical studies of the liver in acute and chronic lead stearate poisoning. 1981 Ann Univ Mariae Curie Sklodowska Med pmid:7052786
Taylor AJ Erythrocyte membrane fatty acid composition in hypercholesterolaemia. 1994 Ann. Clin. Biochem. pmid:7979101