stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Urticaria D014581 13 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Adenoma D000236 40 associated lipids
Leprosy D007918 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Tremor D014202 15 associated lipids
Lymphadenitis D008199 8 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Bangudu AB and Pilpel N Effects of composition, moisture and stearic acid on the plasto-elasticity and tableting of paracetamol-microcrystalline cellulose mixtures. 1985 J. Pharm. Pharmacol. pmid:2862234
Yasuda H et al. Biphasic liberation of arachidonic and stearic acids during cerebral ischemia. 1985 J. Neurochem. pmid:2987409
Noy N and Zakim D Fatty acids bound to unilamellar lipid vesicles as substrates for microsomal acyl-CoA ligase. 1985 Biochemistry pmid:2931113
Enk L et al. High-dose depot-medroxyprogesterone acetate--effects on the fatty acid composition of serum lecithin and cholesterol ester. 1985 Gynecol. Oncol. pmid:2933308
Canonico PL et al. Arachidonate stimulates prolactin release in vitro: a role for the fatty acid and its metabolites as intracellular regulator(s) in mammotrophs. 1985 Endocrinology pmid:2981065
Onoda T et al. Antitumor activity of D-mannosamine in vitro: cytotoxic effect produced by mannosamine in combination with free fatty acids on human leukemia T-cell lines. 1985 Jpn. J. Clin. Oncol. pmid:3877190
Shanson DC et al. Erythromycin stearate, 1.5 g, for the oral prophylaxis of streptococcal bacteraemia in patients undergoing dental extraction: efficacy and tolerance. 1985 J. Antimicrob. Chemother. pmid:3882657
Boiron F et al. A comparison of substrate-dependent fatty acyl-CoA synthetase activities and ATP hydrolysis in membrane pellets from normal and trembler mouse sciatic nerves. 1985 Neurochem. Int. pmid:20492990
Jones PJ et al. Whole body oxidation of dietary fatty acids: implications for energy utilization. 1985 Am. J. Clin. Nutr. pmid:3933323
Roughan PG Phosphatidylglycerol and chilling sensitivity in plants. 1985 Plant Physiol. pmid:16664127
Kaplan E and Ansari K High-performance liquid chromatography as a tool for identification of linolenic acid hydroperoxide prepared with soybean lipoxygenase. 1985 J. Chromatogr. pmid:3937844
Maiti H and Haye KR Does detection of chlamydial antibodies by microimmunofluorescence help in managing chlamydial lower genital tract infection in women? 1985 Genitourin Med pmid:3891584
Walker KA and Harwood JL Localization of chloroplastic fatty acid synthesis de novo in the stroma. 1985 Biochem. J. pmid:3994672
Jones PJ et al. Absorption of 13C-labeled stearic, oleic, and linoleic acids in humans: application to breath tests. 1985 J. Lab. Clin. Med. pmid:3998617
Bertrand G et al. [The value of polyglactin 910 combined with a resorbable bone wax for filling periodontal bone defects]. 1985 Actual Odontostomatol (Paris) pmid:2425560
Wadström T et al. Hydrophobized wound dressing in the treatment of experimental Staphylococcus aureus infections in the young pig. 1985 Acta Pathol Microbiol Immunol Scand B pmid:2417448
Wood CB et al. Reduction in the stearic to oleic acid ratio in the circulating red blood cells: a possible tumour marker in solid human neoplasms. 1985 Eur J Surg Oncol pmid:4007173
Harrison GA et al. Resistance in oral streptococci after repeated three-dose erythromycin prophylaxis. 1985 J. Antimicrob. Chemother. pmid:4008379
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Crutchley DJ Hydroxyeicosatetraenoic acids and other unsaturated fatty acids inhibit endotoxin-induced thromboplastin activity in human monocytes. 1985 Biochem. Biophys. Res. Commun. pmid:2865954
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Colombo I and Carli F Comparative evaluation of structure and micromeritics properties of magnesium stearate. 1984 Farmaco Prat pmid:6510514
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Buttke TM and Cuchens MA Inhibition of lymphocyte proliferation by free fatty acids. II. Toxicity of stearic acid towards phytohaemagglutinin-activated T cells. 1984 Immunology pmid:6333387
Walstad RA and Hellum KB Penetration of erythromycin in respiratory tract infections. 1984 Acta Otolaryngol Suppl pmid:6333775
Shanson DC et al. The pharmacokinetics and tolerance of oral erythromycin stearate compared with erythromycin ethylsuccinate: implications for preventing endocarditis. 1984 J. Antimicrob. Chemother. pmid:6334070
Tjandramaga TB et al. Relative bioavailability of enteric coated pellets, stearate and ethylsuccinate formulations of erythromycin. 1984 Pharmacology pmid:6334320
Aylsworth CF et al. Promotion of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis by high dietary fat in the rat: possible role of intercellular communication. 1984 J. Natl. Cancer Inst. pmid:6422115
Kido H et al. Inhibition of chymase activity by long chain fatty acids. 1984 Arch. Biochem. Biophys. pmid:6424574
Feix JB et al. An electron-electron double-resonance study of interactions between [14N]- and [15N]stearic acid spin-label pairs: lateral diffusion and vertical fluctuations in dimyristoylphosphatidylcholine. 1984 Biochemistry pmid:6329270
Ohki K et al. Effect of alpha-tocopherol on lipid peroxidation and acyl chain mobility of liver microsomes from vitamin E-difficient rat. 1984 J. Nutr. Sci. Vitaminol. pmid:6092586
Lem NW and Stumpf PK In Vitro Fatty Acid Synthesis and Complex Lipid Metabolism in the Cyanobacterium, Anabaena Variabilis: II. Acyl Transfer and Complex Lipid Formation. 1984 Plant Physiol. pmid:16663690
Francis H et al. Severe vascular spasm due to erythromycin-ergotamine interaction. 1984 Clin. Rheumatol. pmid:6236021
Bhakoo KK et al. Regional studies of changes in brain fatty acids following experimental ischaemia and reperfusion in the gerbil. 1984 J. Neurochem. pmid:6236282
Abumrad NA et al. Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. 1984 J. Biol. Chem. pmid:6746632
Zoeller RA and Wood R Effects of cyclopropene fatty acids on the lipid composition of the Morris hepatoma 7288C. 1984 Lipids pmid:6431218
Sivarajan M et al. Regulation of intracellular arachidonate in normal and stressed endothelial cells. 1984 Biochim. Biophys. Acta pmid:6433983
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Dixon JF and Hokin LE Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase. 1984 J. Biol. Chem. pmid:6438097
Forsberg NE et al. Roles of acetate and its interactions with glucose and lactate in cow mammary tissue. 1984 J. Dairy Sci. pmid:6438200
Desudchit P et al. Rifampicin-erythromycin combination for the treatment of gonococcal urethritis in men. 1984 Southeast Asian J. Trop. Med. Public Health pmid:6441265
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Fenyvest E et al. Cyclodextrin polymer, a new tablet disintegrating agent. 1984 Pharmazie pmid:6494226
Junginger H [The ratio of free and fixed interlamellar water as quality criteria for O/W creams]. 1984 Pharmazie pmid:6504995
Kennett FF et al. Inhibition of myocardial rotenone-insensitive NADH cytochrome c reductase by amphiphilic compounds. 1984 Am. J. Physiol. pmid:6507637
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Shechter Y and Henis YI Cis-unsaturated fatty acids induce both lipogenesis and calcium binding in adipocytes. 1984 Biochim. Biophys. Acta pmid:6477975
Bogdanov AA et al. Immobilization of alpha-chymotrypsin on sucrose stearate--palmitate containing liposomes. 1984 FEBS Lett. pmid:6479332
Junginger HE Colloidal structures of O/W creams. 1984 Pharm Weekbl Sci pmid:6483570
Mogelson S and Lange LG Nonoxidative ethanol metabolism in rabbit myocardium: purification to homogeneity of fatty acyl ethyl ester synthase. 1984 Biochemistry pmid:6487591
Boakes AJ et al. Treatment of uncomplicated gonorrhoea in women with a combination of rifampicin and erythromycin. 1984 Br J Vener Dis pmid:6487986
Fernandes AC et al. Enhancement of human polymorphonuclear leucocyte motility by erythromycin in vitro and in vivo. 1984 S. Afr. Med. J. pmid:6463793
Yoshida S and Takeshita M Arachidoyl- and arachidonoyl-CoA elongation mechanism in swine cerebral microsomes. 1984 Biochim. Biophys. Acta pmid:6466693
Waldman SA et al. Acyl composition and phospholipase activities in plasma membranes isolated from rat embryos. 1984 Int. J. Biochem. pmid:6468725
Slevin ML et al. The pharmacokinetics of subcutaneous bolus cytosine arabinoside in an arachis oil plus aluminium distearate suspension. 1984 Invest New Drugs pmid:6511233
Vandermeerschen-Doizé F and Paquay R Effects of continuous long-term intravenous infusion of long-chain fatty acids on feeding behaviour and blood components of adult sheep. 1984 Appetite pmid:6517567
Hunter JM and Sommerville RG Erythromycin stearate in treating chlamydial infection of the cervix. 1984 Br J Vener Dis pmid:6518350
Farkas T Adaptation of fatty acid composition to temperature--a study on carp (Cyprinus carpio L.) liver slices. 1984 Comp. Biochem. Physiol., B pmid:6518757
Magill A and Becker AR Spectrophotometric method for quantitation of peroxides in sorbitan monooleate and monostearate. 1984 J Pharm Sci pmid:6520780
Ueda A et al. Experimental study on the pathological changes in lung tissue caused by zinc stearate dust. 1984 Ind Health pmid:6526700
Rosén C et al. Acute otitis media in older children and adults treated with phenoxymethyl penicillin or erythromycin stearate. Bacteriological and immunological aspects. 1983 Sep-Oct Acta Otolaryngol. pmid:6416018
Robson HG et al. Comparison of rosaramicin and erythromycin stearate for treatment of cervical infection with Chlamydia trachomatis. 1983 Jul-Sep Sex Transm Dis pmid:6648747
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Hundrieser KE et al. Distribution of trans-octadecenoic acid in the major glycerolipids of human milk. 1983 J. Pediatr. Gastroenterol. Nutr. pmid:6644446
Hikal AH Dissolution of meprobamate from various tablet formulations. 1983 Pharmazie pmid:6669616
Kohn MC and Garfinkel D Computer simulation of metabolism in palmitate-perfused rat heart. I. Palmitate oxidation. 1983 Ann Biomed Eng pmid:6592996
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Erman A et al. Phospholipase A2 inhibitors. Differential inhibition of fatty acid acylation into kidney lipids by mepacrine and p-bromophenacyl bromide. 1983 Biochem. Pharmacol. pmid:6870935
Flood MT et al. Vitamin A utilization in human retinal pigment epithelial cells in vitro. 1983 Invest. Ophthalmol. Vis. Sci. pmid:6885309
Edwards EK and Edwards EK Allergic reaction to triethanolamine stearate in a sunscreen. 1983 Cutis pmid:6831931
Chapkin RS et al. Characterization of the individual phospholipids and their fatty acids in serum and high-density lipoprotein of the renal patient on long-term maintenance hemodialysis. 1983 J. Lab. Clin. Med. pmid:6833842
Hillmar I et al. Influence of fatty acids on microsomal diacylglycerol acyltransferase activity in primary cultures of hepatocytes. 1983 Hoppe-Seyler's Z. Physiol. Chem. pmid:6840704
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Streichman S et al. Unique profile for erythrocyte membrane acetylcholinesterase in hereditary spherocytosis. 1983 Biochim. Biophys. Acta pmid:6849970
Sobel JD et al. Legionella bozemanii. Still another cause of pneumonia. 1983 JAMA pmid:6854903
Stults BM et al. Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease. 1983 South. Med. J. pmid:6857302
Yoshida S et al. Brain free fatty acids, edema, and mortality in gerbils subjected to transient, bilateral ischemia, and effect of barbiturate anesthesia. 1983 J. Neurochem. pmid:6403669
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