stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Urticaria D014581 13 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Adenoma D000236 40 associated lipids
Leprosy D007918 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Tremor D014202 15 associated lipids
Lymphadenitis D008199 8 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Ocloo FCK et al. Effects of stearic acid and gamma irradiation, alone and in combination, on pasting properties of high amylose maize starch. 2016 Food Chem pmid:26212935
Jójárt I et al. Study of the compressibility of chewing gum and its applicability as an oral drug delivery system. 2016 Pharm Dev Technol pmid:25673279
Patadia R et al. Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets. 2016 Pharm Dev Technol pmid:25566928
Souza AF et al. Waste Soybean Oil and Corn Steep Liquor as Economic Substrates for Bioemulsifier and Biodiesel Production by Candida lipolytica UCP 0998. 2016 Int J Mol Sci pmid:27669227
Teh SS et al. Incorporation of Palmitic Acid or Stearic Acid into Soybean Oils Using Enzymatic Interesterification. 2016 J Oleo Sci pmid:27477075
Sun Y et al. Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study. 2016 J. Lipid Res. pmid:27371261
Du H et al. Modification of the fatty acid composition in Arabidopsis and maize seeds using a stearoyl-acyl carrier protein desaturase-1 (ZmSAD1) gene. 2016 BMC Plant Biol. pmid:27297560
Sorigué D et al. Microalgae Synthesize Hydrocarbons from Long-Chain Fatty Acids via a Light-Dependent Pathway. 2016 Plant Physiol. pmid:27288359
Jeyanathan J et al. Biohydrogenation of 22:6n-3 by Butyrivibrio proteoclasticus P18. 2016 BMC Microbiol. pmid:27283157
Hashemi Goradel N et al. Improvement of Liver Cell Therapy in Rats by Dietary Stearic Acid. 2016 Iran. Biomed. J. pmid:27090202
Ma Y et al. Silymarin-Loaded Nanoparticles Based on Stearic Acid-Modified Bletilla striata Polysaccharide for Hepatic Targeting. 2016 Molecules pmid:26938513
Šrámek J et al. p38 MAPK Is Activated but Does Not Play a Key Role during Apoptosis Induction by Saturated Fatty Acid in Human Pancreatic β-Cells. 2016 Int J Mol Sci pmid:26861294
Cerf ME and Herrera E High Fat Diet Administration during Specific Periods of Pregnancy Alters Maternal Fatty Acid Profiles in the Near-Term Rat. 2016 Nutrients pmid:26742067
Fretts AM et al. Associations of Plasma Phospholipid SFAs with Total and Cause-Specific Mortality in Older Adults Differ According to SFA Chain Length. 2016 J. Nutr. pmid:26701797
Sergeant S et al. Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans. 2016 Br. J. Nutr. pmid:26615716
Garba L et al. Heterologous Expression of PA8FAD9 and Functional Characterization of a Δ9-Fatty Acid Desaturase from a Cold-Tolerant Pseudomonas sp. A8. 2016 Mol. Biotechnol. pmid:27629791
Mazel V et al. Reevaluation of the diametral compression test for tablets using the flattened disc geometry. 2016 Int J Pharm pmid:27702696
Nie H et al. Impact of Metallic Stearates on Disproportionation of Hydrochloride Salts of Weak Bases in Solid-State Formulations. 2016 Mol. Pharm. pmid:27542728
Passerini N et al. Development of microparticles for oral administration of the non-conventional radical scavenger IAC and testing in an inflammatory rat model. 2016 Int J Pharm pmid:27530293
Karthik S et al. Quillaja saponin: A prospective emulsifier for the preparation of solid lipid nanoparticles. 2016 Colloids Surf B Biointerfaces pmid:27521748
Ghate VM et al. Nanostructured lipid carriers for the topical delivery of tretinoin. 2016 Eur J Pharm Biopharm pmid:27519827
Ohiri RC and Bassey EE Gas Chromatography-Mass Spectrometry Analysis of Constituent Oil from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), from Nigeria. 2016 Int J Med Mushrooms pmid:27481303
Monteyne T et al. Stearic acid and high molecular weight PEO as matrix for the highly water soluble metoprolol tartrate in continuous twin-screw melt granulation. 2016 Int J Pharm pmid:27452420
Ariyasu A et al. Delay effect of magnesium stearate on tablet dissolution in acidic medium. 2016 Int J Pharm pmid:27444551
Schulze C et al. A one-stage cultivation process for lipid- and carbohydrate-rich biomass of Scenedesmus obtusiusculus based on artificial and natural water sources. 2016 Bioresour. Technol. pmid:27394996
Mužíková J and Kubíčková A A study of compressibility and compactibility of directly compressible tableting materials containing tramadol hydrochloride. 2016 Acta Pharm pmid:27383891
Hu Y et al. Sequential delivery of therapeutic agents using a rationally designed disulfide-linked glycolipid-like nanocarrier. 2016 Oncotarget pmid:27825127
Billès E et al. Cellulose oligomers production and separation for the synthesis of new fully bio-based amphiphilic compounds. 2016 Carbohydr Polym pmid:27577903
Krasnou I et al. Permeability of water and oleic acid in composite films of phase separated polypropylene and cellulose stearate blends. 2016 Carbohydr Polym pmid:27516292
Liu L et al. Decreasing high postprandial stearic acid in impaired fasting glucose by dietary regulation. 2016 Eur J Clin Nutr pmid:26733041
Thilakarathna SH et al. Investigations of in vitro bioaccessibility from interesterified stearic and oleic acid-rich blends. 2016 Food Funct pmid:26961726
Ma F et al. Improvement of β-TCP/PLLA biodegradable material by surface modification with stearic acid. 2016 Mater Sci Eng C Mater Biol Appl pmid:26952440
Zhang C et al. Design and evaluation of an innovative floating and bioadhesive multiparticulate drug delivery system based on hollow structure. 2016 Int J Pharm pmid:26943975
Zhang Y et al. CO2/pH-Controllable Viscoelastic Nanostructured Fluid Based on Stearic Acid Soap and Bola-Type Quaternary Ammonium Salt. 2016 Langmuir pmid:26907546
Wang S et al. Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells. 2016 Biochem. Biophys. Res. Commun. pmid:26879142
Lohan SB et al. Investigation of cutaneous penetration properties of stearic acid loaded to dendritic core-multi-shell (CMS) nanocarriers. 2016 Int J Pharm pmid:26853315
Stahlberg S et al. Probing the Role of Ceramide Headgroup Polarity in Short-Chain Model Skin Barrier Lipid Mixtures by ²H Solid-State NMR Spectroscopy. 2016 Langmuir pmid:26828109
Lavergne SN et al. Potential cutaneous hypersensitivity reaction to an inactive ingredient of thyroid hormone supplements in a dog. 2016 Vet. Dermatol. pmid:26748887
Baig MS et al. Application of Box-Behnken design for preparation of levofloxacin-loaded stearic acid solid lipid nanoparticles for ocular delivery: Optimization, in vitro release, ocular tolerance, and antibacterial activity. 2016 Int. J. Biol. Macromol. pmid:26740466
Adler C et al. Molecularly designed lipid microdomains for solid dispersions using a polymer/inorganic carrier matrix produced by hot-melt extrusion. 2016 Int J Pharm pmid:26721729
Wood MH et al. Comparative Adsorption of Saturated and Unsaturated Fatty Acids at the Iron Oxide/Oil Interface. 2016 Langmuir pmid:26707597
Bothun GD et al. Cooperative effects of fatty acids and n-butanol on lipid membrane phase behavior. 2016 Colloids Surf B Biointerfaces pmid:26700234
Cárdenas V et al. Strategy for design NIR calibration sets based on process spectrum and model space: An innovative approach for process analytical technology. 2015 J Pharm Biomed Anal pmid:26001330
de Sousa FF et al. Low-temperature phase transformation studies in the stearic acid: C form. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25909902
Bootello MA et al. Effect of solvents on the fractionation of high oleic-high stearic sunflower oil. 2015 Food Chem pmid:25442612
Thakral NK et al. Compression-induced crystallization of amorphous indomethacin in tablets: characterization of spatial heterogeneity by two-dimensional X-ray diffractometry. 2015 Mol. Pharm. pmid:25438193
Imran M and Nadeem M Triacylglycerol composition, physico-chemical characteristics and oxidative stability of interesterified canola oil and fully hydrogenated cottonseed oil blends. 2015 Lipids Health Dis pmid:26510410
Conde-Sieira M et al. Hypothalamic fatty acid sensing in Senegalese sole (Solea senegalensis): response to long-chain saturated, monounsaturated, and polyunsaturated (n-3) fatty acids. 2015 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:26468264
Iwao Y [Efficient Pharmaceutical Formulation Designs and Their Development Using Mathematical and Statistical Analysis]. 2015 Yakugaku Zasshi pmid:26423868
Dong X et al. [Analysis of meibum by gas chromatography-mass spectrometry]. 2015 Zhonghua Yan Ke Za Zhi pmid:26693651