stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Urticaria D014581 13 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Adenoma D000236 40 associated lipids
Leprosy D007918 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Tremor D014202 15 associated lipids
Lymphadenitis D008199 8 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
WIRTH JC and ANAND SR THE FATTY ACIDS OF TRICHOPHYTON RUBRUM. 1964 Can. J. Microbiol. pmid:14124857
BERGELSON LD et al. COMPLETE STRUCTURAL ANALYSIS OF FATTY ACID MIXTURES BY THIN-LAYER CHROMATOGRAPHY. 1964 J. Chromatogr. pmid:14205937
HAMMONDS TW and SHONE G THE SEPARATION OF FATTY ACID METHYL ESTERS (INCLUDING "CRITICAL PAIRS") BY THIN-LAYER PARTITION CHROMATOGRAPHY. 1964 J. Chromatogr. pmid:14205938
PILZ H and JATZKEWITZ H [DETERMINATION OF C18- AND C24-SPHINGOMYELIN BY THIN-LAYER CHROMATOGRAPHY IN NORMAL AND PATHOLOGICAL BRAINS, INCLUDING A CASE OF NIEMANN-PICK DISEASE]. 1964 J. Neurochem. pmid:14206462
ELLEFSON RD and MASON HL EFFECTS OF DEFICIENCY AND EXCESS OF THYROID HORMONE ON THE DISTRIBUTION OF FATTY ACIDS IN LIPIDS OF THE RAT. 1964 Endocrinology pmid:14206987
BERGMANN ED et al. THIN-LAYER CHROMATOGRAPHY OF BETA-SITOSTERYL ESTERS. 1964 J. Chromatogr. pmid:14207024
WILLEBRANDS AF MYOCARDIAL EXTRACTION OF INDIVIDUAL NON-ESTERIFIED FATTY ACIDS, ESTERIFIED FATTY ACIDS AND ACETOACETATE IN THE FASTING HUMAN. 1964 Clin. Chim. Acta pmid:14230940
SKIPSKI VP and MOREHOUSE MG THE INCORPORATION OF INGESTED GLYCEROL-C14 INTO THE LIPIDS ON THE RAT. 1964 Arch. Biochem. Biophys. pmid:14234504
HOLLOWAY PW and WAKIL SJ SYNTHESIS OF FATTY ACIDS IN ANIMAL TISSUES. II. THE OCCURRENCE AND BIOSYNTHESIS OF CIS-VACCENIC ACID. 1964 J. Biol. Chem. pmid:14235526
DAVIDOFF F and KORN ED THE CONVERSION OF LONG CHAIN SATURATED FATTY ACIDS TO THEIR ALPHA, BETA-UNSATURATED, BETA, GAMMA-UNSATURATED, AND BETA-HYDROXY DERIVATIVES BY ENZYMES FROM THE CELLULAR SLIME MOLD, DICTYOSTELIUM DISCOIDEUM. 1964 J. Biol. Chem. pmid:14235527
VROMAN L and LUKOSEVICIUS A ELLIPSOMETER RECORDINGS OF CHANGES IN OPTICAL THICKNESS OF ADSORBED FILMS ASSOCIATED WITH SURFACE ACTIVATION OF BLOOD CLOTTING. 1964 Nature pmid:14236308
PORTMAN OW and SUGANO M FACTORS INFLUENCING THE LEVEL AND FATTY ACID SPECIFICITY OF THE CHOLESTEROL ESTERIFICATION ACTIVITY IN HUMAN PLASMA. 1964 Arch. Biochem. Biophys. pmid:14236639
TIETZ A et al. A NEW PTERIDINE-REQUIRING ENZYME SYSTEM FOR THE OXIDATION OF GLYCERYL ETHERS. 1964 J. Biol. Chem. pmid:14247652
OVERATH P and STUMPF PK FAT METABOLISM IN HIGHER PLANTS. 23. PROPERTIES OF A SOLUBLE FATTY ACID SYNTHETASE FROM AVOCADO MESOCARP. 1964 J. Biol. Chem. pmid:14247655
TOVE SB TOXICITY OF SATURATED FAT. 1964 J. Nutr. pmid:14227501
CLAYTON RB et al. THE INTESTINAL ABSORPTION OF CHOLESTEROL, ITS ESTERS AND SOME RELATED STEROLS AND ANALOGUES IN THE ROAC, EURYCOTIS FLORIDANA. 1964 Comp. Biochem. Physiol. pmid:14167530
FULCO AJ and BLOCH K COFACTOR REQUIREMENTS FOR THE FORMATION OF DELTA-9-UNSATURATED FATTY ACIDS IN MYCOBACTERIUM PHLEI. 1964 J. Biol. Chem. pmid:14167617
HOAK JC STRUCTURE OF THROMBI PRODUCED BY INJECTIONS OF FATTY ACIDS. 1964 Br J Exp Pathol pmid:14119273
ENGELMANN D et al. [CONCERNING THE RESORPTION AND METABOLISM OF SOME 1-14C-LABELLED FREE FATTY ACIDS IN YOUNG RABBITS]. 1964 Clin. Chim. Acta pmid:14122499
ELSBACH P COMPARISON OF UPTAKE OF PALMITIC, STEARIC, OLEIC AND LINOLEIC ACID BY POLYMORPHONUCLEAR LEUKOCYTES. 1964 Biochim. Biophys. Acta pmid:14124760