| MeSH term | MeSH ID | Detail |
|---|---|---|
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Snoeren TA et al. | Multidisciplinary approach to unravelling the relative contribution of different oxylipins in indirect defense of Arabidopsis thaliana. | 2009 | J. Chem. Ecol. | pmid:19798534 |
| Atherton HJ et al. | Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse. | 2009 | Mol. Syst. Biol. | pmid:19357638 |
| Crouzier D et al. | Pulsed electromagnetic field at 9.71 GHz increase free radical production in yeast (Saccharomyces cerevisiae). | 2009 | Pathol. Biol. | pmid:18321660 |
| Sahoo RR and Biswas SK | Frictional response of fatty acids on steel. | 2009 | J Colloid Interface Sci | pmid:19232636 |
| MartÃnez-Force E et al. | Influence of specific fatty acids on the asymmetric distribution of saturated fatty acids in sunflower (Helianthus annuus L.) triacylglycerols. | 2009 | J. Agric. Food Chem. | pmid:19166295 |
| Chen JJ et al. | seco-Abietane diterpenoids, a phenylethanoid derivative, and antitubercular constituents from Callicarpa pilosissima. | 2009 | J. Nat. Prod. | pmid:19193025 |
| Peters GH et al. | Effects of fatty acid inclusion in a DMPC bilayer membrane. | 2009 | J Phys Chem B | pmid:19195101 |
| Sugisawa K et al. | Rapid quantitative analysis of magnesium stearate in pharmaceutical powders and solid dosage forms by atomic absorption: method development and application in product manufacturing. | 2009 | J Pharm Biomed Anal | pmid:19195812 |
| Tuomasjukka SS et al. | Regio-distribution of stearic acid is not conserved in chylomicrons after ingestion of randomised, stearic acid-rich fat in a single meal. | 2009 | J. Nutr. Biochem. | pmid:19195862 |
| Parlati C et al. | Pulmonary spray dried powders of tobramycin containing sodium stearate to improve aerosolization efficiency. | 2009 | Pharm. Res. | pmid:19184617 |
| Matharu Z et al. | Langmuir-Blodgett film based on MEH-PPV for cholesterol biosensor. | 2009 | Anal. Chim. Acta | pmid:19185127 |
| Roberts R et al. | Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans. | 2009 | Diabetologia | pmid:19252892 |
| Yuan H et al. | Strategic approaches for improving entrapment of hydrophilic peptide drugs by lipid nanoparticles. | 2009 | Colloids Surf B Biointerfaces | pmid:19185474 |
| Cha D et al. | Analysis of fatty acids in sputum from patients with pulmonary tuberculosis using gas chromatography-mass spectrometry preceded by solid-phase microextraction and post-derivatization on the fiber. | 2009 | J Chromatogr A | pmid:19171347 |
| Mermigkis C et al. | A green oral appliance. | 2009 | Eur. Respir. J. | pmid:19181918 |
| Boros LG et al. | Ethanol diversely alters palmitate, stearate, and oleate metabolism in the liver and pancreas of rats using the deuterium oxide single tracer. | 2009 | Pancreas | pmid:19248221 |
| Ishitsuka Y et al. | Effects of bolus injection of soybean-based fat emulsion and fatty acids on pulmonary gas exchange function. | 2009 | Biol. Pharm. Bull. | pmid:19252304 |
| Pingali KC et al. | Use of a static eliminator to improve powder flow. | 2009 | Int J Pharm | pmid:19266628 |
| Shehab-El-Deen MA et al. | Cryotolerance of bovine blastocysts is affected by oocyte maturation in media containing palmitic or stearic acid. | 2009 | Reprod. Domest. Anim. | pmid:18992093 |
| Slobodkina GB et al. | Geoglobus acetivorans sp. nov., an iron(III)-reducing archaeon from a deep-sea hydrothermal vent. | 2009 | Int. J. Syst. Evol. Microbiol. | pmid:19628601 |
| Asgary S et al. | Evaluation of fatty acid content of some Iranian fast foods with emphasis on trans fatty acids. | 2009 | Asia Pac J Clin Nutr | pmid:19713177 |
| Ashby RD et al. | Methyl-branched poly(hydroxyalkanoate) biosynthesis from 13-methyltetradecanoic acid and mixed isostearic acid isomer substrates. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19644690 |
| Yamamura T et al. | Effects of automated external lubrication on tablet properties and the stability of eprazinone hydrochloride. | 2009 | Int J Pharm | pmid:19059327 |
| Plumley C et al. | Nifedipine nanoparticle agglomeration as a dry powder aerosol formulation strategy. | 2009 | Int J Pharm | pmid:19015016 |
| Burkhardt M et al. | Macroscopic properties and microstructure of HSA based organogels: sensitivity to polar additives. | 2009 | J Colloid Interface Sci | pmid:19144353 |
| Chen Y et al. | Observation of an amorphous calcium carbonate precursor on a stearic acid monolayer formed during the biomimetic mineralization of CaCO(3). | 2009 | Langmuir | pmid:19099353 |
| Mäe M et al. | A stearylated CPP for delivery of splice correcting oligonucleotides using a non-covalent co-incubation strategy. | 2009 | J Control Release | pmid:19105971 |
| Chen JM et al. | [Comparison of seed oil physicochemical characteristics among three cultivars of Jatropha curcas L]. | 2009 | Ying Yong Sheng Tai Xue Bao | pmid:20353052 |
| Hommelberg PP et al. | Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:18957619 |
| Gohel M and Bariya SH | Advanced formulation design of venlafaxine hydrochloride coated and triple-layer tablets containing hypromellose. | 2009 | Pharm Dev Technol | pmid:19883254 |
| Chen CY et al. | Chemical constituents from the whole plant of Gaultheria itoana Hayata. | 2009 | Chem. Biodivers. | pmid:19842133 |
| Pingali KC et al. | Practical methods for improving flow properties of active pharmaceutical ingredients. | 2009 | Drug Dev Ind Pharm | pmid:19929205 |
| Le Guédard M et al. | PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast. | 2009 | FEBS J. | pmid:19796168 |
| Staiger H et al. | Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans. | 2009 | Diabetes | pmid:19074989 |
| Kadotani A et al. | Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:19755671 |
| Bao Y et al. | Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers. | 2009 | J. Proteome Res. | pmid:19714868 |
| Castro ML et al. | Bioassay guided purification of the antimicrobial fraction of a Brazilian propolis from Bahia state. | 2009 | BMC Complement Altern Med | pmid:19643008 |
| Okada K et al. | Effect of fatty acids added to the milk replacer on white scour and excretion of fatty acids in Holstein calves. | 2009 | Anim. Sci. J. | pmid:20163618 |
| Madgulkar AR et al. | Formulation and optimization of sustained release tablets of venlafaxine resinates using response surface methodology. | 2009 | Indian J Pharm Sci | pmid:20502544 |
| Mukherjee S et al. | Solid lipid nanoparticles: a modern formulation approach in drug delivery system. | 2009 | Indian J Pharm Sci | pmid:20502539 |
| Arayne MS et al. | Spectrophotometric Quantitation of Metformin in Bulk Drug and Pharmaceutical Formulations using Multivariate Technique. | 2009 | Indian J Pharm Sci | pmid:20490308 |
| Leonardi R et al. | Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. | 2009 | J. Biol. Chem. | pmid:19666474 |
| Keny RV et al. | Formulation and evaluation of once daily minocycline hydrochloride extended release matrix tablets. | 2009 | Indian J Pharm Sci | pmid:20490297 |
| Jacob S and Shirwaikar A | Preparation and evaluation of microencapsulated fast melt tablets of ambroxol hydrochloride. | 2009 | Indian J Pharm Sci | pmid:20490294 |
| Roni MA et al. | Formulation and in vitro Evaluation of Alfuzosin Extended Release Tablets Using Directly Compressible Eudragit. | 2009 | Indian J Pharm Sci | pmid:20490290 |
| Costa MC et al. | The solid-liquid phase diagrams of binary mixtures of consecutive, even saturated fatty acids. | 2009 | Chem. Phys. Lipids | pmid:19520067 |
| Prajapati ST et al. | Studies on formulation and in vitro evaluation of floating matrix tablets of domperidone. | 2009 | Indian J Pharm Sci | pmid:20177450 |
| Puzanowska-Tarasiewicz H et al. | Spectroscopic and electrochemical analysis of psychotropic drugs. | 2009 | Indian J Pharm Sci | pmid:20177449 |
| Wei Y et al. | Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells. | 2009 | Mol. Cell. Biochem. | pmid:19444596 |
| Mahmoud AM et al. | Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate. | 2009 | Int J Anal Chem | pmid:20140080 |
| Evans LM et al. | Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice. | 2009 | Clin. Exp. Metastasis | pmid:19267249 |
| Mahmoud AM | New sensitive kinetic spectrophotometric methods for determination of omeprazole in dosage forms. | 2009 | Int J Anal Chem | pmid:20140076 |
| Darwish IA et al. | New spectrophotometric and fluorimetric methods for determination of fluoxetine in pharmaceutical formulations. | 2009 | Int J Anal Chem | pmid:20107560 |
| Darwish IA et al. | Simple spectrophotometric method for determination of paroxetine in tablets using 1,2-naphthoquinone-4-sulphonate as a chromogenic reagent. | 2009 | Int J Anal Chem | pmid:20107559 |
| Guo L and Qing Li G | Olfactory perception of oviposition-deterring fatty acids and their methyl esters by the Asian corn borer, Ostrinia furnacalis. | 2009 | J. Insect Sci. | pmid:20053122 |
| Evans LM et al. | Stearate preferentially induces apoptosis in human breast cancer cells. | 2009 | Nutr Cancer | pmid:19838949 |
| Mukherjee S and Datta A | Morphology and structural evolution in cobalt stearate Langmuir-Blodgett films. | 2009 | J Nanosci Nanotechnol | pmid:19928206 |
| Yarkala S et al. | Role of excipients on N-oxide raloxifene generation from raloxifene-excipients binary mixtures. | 2009 | Chem. Pharm. Bull. | pmid:19801885 |
| Jayakumar OD et al. | Water dispersible Fe3O4 nanoparticles carrying doxorubicin for cancer therapy. | 2009 | J Nanosci Nanotechnol | pmid:19908532 |
| Fujita M et al. | Generation of formaldehyde by pharmaceutical excipients and its absorption by meglumine. | 2009 | Chem. Pharm. Bull. | pmid:19801864 |
| Gängler P et al. | In vitro effect of fluoride oral hygiene tablets on artificial caries lesion formation and remineralization in human enamel. | 2009 | BMC Oral Health | pmid:19799785 |
| Amorim EA et al. | Effect of cholesterol or cholesteryl conjugates on the cryosurvival of bull sperm. | 2009 | Cryobiology | pmid:19159623 |
| Yonezawa T et al. | Saturated fatty acids stimulate and insulin suppresses BMCP1 expression in bovine mammary epithelial cells. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19852928 |
| Hellemans KH et al. | Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase. | 2009 | PLoS ONE | pmid:19787047 |
| Artwohl M et al. | Fatty acids induce apoptosis in human smooth muscle cells depending on chain length, saturation, and duration of exposure. | 2009 | Atherosclerosis | pmid:18597758 |
| Masuoka HC et al. | Mcl-1 degradation during hepatocyte lipoapoptosis. | 2009 | J. Biol. Chem. | pmid:19734538 |
| Rittermeier A et al. | The formation of colloidal copper nanoparticles stabilized by zinc stearate: one-pot single-step synthesis and characterization of the core-shell particles. | 2009 | Phys Chem Chem Phys | pmid:19756292 |
| Jiang L et al. | Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway. | 2009 | PLoS ONE | pmid:19727392 |
| Lakshmi RV and Basu BJ | Fabrication of superhydrophobic sol-gel composite films using hydrophobically modified colloidal zinc hydroxide. | 2009 | J Colloid Interface Sci | pmid:19720382 |
| Alagna F et al. | Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development. | 2009 | BMC Genomics | pmid:19709400 |
| Lozano MM and Longo ML | Microbubbles coated with disaturated lipids and DSPE-PEG2000: phase behavior, collapse transitions, and permeability. | 2009 | Langmuir | pmid:19708150 |
| Spaniol B et al. | Compressional behavior of a mixture of granules containing high load of Phyllanthus niruri spray-dried extract and granules of adjuvants: comparison between eccentric and rotary tablet machines. | 2009 | AAPS PharmSciTech | pmid:19662537 |
| Mukherjee S et al. | Chemistry at air/water interface versus reaction in a flask: tuning molecular conformation in thin films. | 2009 | Langmuir | pmid:19708145 |
| Kantartzis K et al. | Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene. | 2009 | Diabetes | pmid:19651814 |
| Andersen CA et al. | Novel generation mycobacterial adjuvant based on liposome-encapsulated monomycoloyl glycerol from Mycobacterium bovis bacillus Calmette-Guérin. | 2009 | J. Immunol. | pmid:19620310 |
| Cha KH et al. | Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia. | 2009 | Arch. Pharm. Res. | pmid:20091273 |
| Staiger K et al. | Protein kinase C iota mediates lipid-induced apoptosis of human coronary artery endothelial cells. | 2009 | Microvasc. Res. | pmid:19327373 |
| Singh R et al. | Mapping quantitative trait loci (QTLs) for fatty acid composition in an interspecific cross of oil palm. | 2009 | BMC Plant Biol. | pmid:19706196 |
| Late SG et al. | Effects of disintegration-promoting agent, lubricants and moisture treatment on optimized fast disintegrating tablets. | 2009 | Int J Pharm | pmid:18778759 |
| Alloatti A et al. | Chemical evaluation of fatty acid desaturases as drug targets in Trypanosoma cruzi. | 2009 | Int. J. Parasitol. | pmid:19249306 |
| Ishikado A et al. | Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells. | 2009 | Atherosclerosis | pmid:19215923 |
| Yang Y et al. | Radial-position-controlled doping of CdS/ZnS core/shell nanocrystals: surface effects and position-dependent properties. | 2009 | Chemistry | pmid:19206119 |
| Durak D and Kalender Y | Fine structure and chemical analysis of the metathoracic scent gland secretion in Graphosoma lineatum (Linnaeus, 1758) (Heteroptera, Pentatomidae). | 2009 | C. R. Biol. | pmid:19200924 |
| Anderson BM and Ma DW | Are all n-3 polyunsaturated fatty acids created equal? | 2009 | Lipids Health Dis | pmid:19664246 |
| Wu Y et al. | Metabonomic profile of rats with acute liver rejection. | 2009 | OMICS | pmid:19196102 |
| Meng W et al. | A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial. | 2009 | Trials | pmid:19419555 |
| Kaye RS et al. | Simultaneously manufactured nano-in-micro (SIMANIM) particles for dry-powder modified-release delivery of antibodies. | 2009 | J Pharm Sci | pmid:19189420 |
| Brach Del Prever EM et al. | UHMWPE for arthroplasty: past or future? | 2009 | J Orthop Traumatol | pmid:19384628 |
| Sobal G et al. | Uptake of 99mTc-labeled chondroitin sulfate by chondrocytes and cartilage: a promising agent for imaging of cartilage degeneration? | 2009 | Nucl. Med. Biol. | pmid:19181270 |
| Marvey BB | Extrudate versus powder silica alumina as support for Re₂O₇ catalyst in the metathesis of seed oil-derivatives - a comparison. | 2009 | Int J Mol Sci | pmid:19333442 |
| Chin PT et al. | Highly luminescent ultranarrow Mn doped ZnSe nanowires. | 2009 | Nano Lett. | pmid:19146460 |
| Begat P et al. | The role of force control agents in high-dose dry powder inhaler formulations. | 2009 | J Pharm Sci | pmid:19067395 |
| Pérez-Berná AJ et al. | Screening a peptide library by DSC and SAXD: comparison with the biological function of the parent proteins. | 2009 | PLoS ONE | pmid:19194494 |
| Kaye RS et al. | Development and testing of particulate formulations for the nasal delivery of antibodies. | 2009 | J Control Release | pmid:19059291 |
| Figueiras AN et al. | Epicuticular lipids induce aggregation in Chagas disease vectors. | 2009 | Parasit Vectors | pmid:19173716 |
| Ren X et al. | Nonionic surfactants are strong inhibitors of cytochrome P450 3A biotransformation activity in vitro and in vivo. | 2009 | Eur J Pharm Sci | pmid:19041719 |
| GarcÃa MS et al. | Development of membrane selective electrode for determination of the antipsychotic sulpiride in pharmaceuticals and urine. | 2009 | Sensors (Basel) | pmid:22408528 |
| Rico S et al. | Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines. | 2009 | J Asthma Allergy | pmid:21437146 |
| Li S et al. | Synthesis and assembly of monodisperse spherical Cu2S nanocrystals. | 2009 | J Colloid Interface Sci | pmid:19007936 |
| Chen CJ et al. | Preparation of Monodisperse Iron Oxide Nanoparticles via the Synthesis and Decomposition of Iron Fatty Acid Complexes. | 2009 | Nanoscale Res Lett | pmid:20628451 |