stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Metabolic Syndrome D024821 44 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Fatty Liver D005234 48 associated lipids
Thrombosis D013927 49 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Reperfusion Injury D015427 65 associated lipids
Neuroblastoma D009447 66 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Mottram AR et al. Fatty acids antagonize bupivacaine-induced I(Na) blockade. 2011 Clin Toxicol (Phila) pmid:21970771
Balducci AG et al. Layered lipid microcapsules for mesalazine delayed-release in children. 2011 Int J Pharm pmid:22001795
Kumar RV and Sinha VR Tailoring of drug delivery of 5-fluorouracil to the colon via a mixed film coated unit system. 2011 Acta Pharm pmid:21945913
Dani KG et al. Structural and functional analyses of a saturated acyl ACP thioesterase, type B from immature seed tissue of Jatropha curcas. 2011 Plant Biol (Stuttg) pmid:21489096
Haghjou N et al. Sustained release intraocular drug delivery devices for treatment of uveitis. 2011 J Ophthalmic Vis Res pmid:22454753
Huang HY et al. Co-delivery of anti-vascular endothelial growth factor siRNA and doxorubicin by multifunctional polymeric micelle for tumor growth suppression. 2011 J Biomed Mater Res A pmid:21465641
Hisazumi J et al. Quantification of pharmaceutical polymorphs and prediction of dissolution rate using theophylline tablet by terahertz spectroscopy. 2011 Chem. Pharm. Bull. pmid:21467671
Guntupalli R et al. Phage Langmuir monolayers and Langmuir-Blodgett films. 2011 Colloids Surf B Biointerfaces pmid:20843668
Saeed M et al. Assessment of diffuse transmission and reflection modes in near-infrared quantification, part 2: DIFFuse reflection information depth. 2011 J Pharm Sci pmid:20862671
Guan Q et al. Preparation and pharmacokinetics of solid lipid nanoparticles loaded with pueraria flavones. 2011 J Control Release pmid:22195890
Zhang Y and Clapp A Overview of stabilizing ligands for biocompatible quantum dot nanocrystals. 2011 Sensors (Basel) pmid:22247651
Jishnu V et al. Formulation and evaluation of cephalexin extended release matrix tablets using 3 factorial design. 2011 J Young Pharm pmid:22224031
Wang K et al. Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. 2011 Int J Nanomedicine pmid:22238509
Du YZ et al. Receptor-mediated gene delivery by folic acid-modified stearic acid-grafted chitosan micelles. 2011 Int J Nanomedicine pmid:21845046
Oosterveer MH et al. Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. 2011 Nutr Metab (Lond) pmid:22201701
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
Wu DJ et al. Metabonomics-based omics study and atherosclerosis. 2011 J Clin Bioinforma pmid:22040517
Walash MI et al. Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids. 2011 Chem Cent J pmid:21996025
Abdulrahman SA and Basavaiah K Sensitive and selective spectrophotometric determination of gabapentin in capsules using two nitrophenols as chromogenic agents. 2011 Int J Anal Chem pmid:21760787
Zenita O and Basavaiah K Utility of N-bromosuccinimide for the titrimetric and spectrophotometric determination of famotidine in pharmaceutical formulations. 2011 Int J Anal Chem pmid:21760785
Almer G et al. Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques. 2011 Int J Nanomedicine pmid:21753879
Brown JD et al. VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. 2011 PLoS ONE pmid:21750705
Fernandez C et al. Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice. 2011 PLoS ONE pmid:21738729
Kalinina OV et al. Combinations of protein-chemical complex structures reveal new targets for established drugs. 2011 PLoS Comput. Biol. pmid:21573205
Amaya KR et al. Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry. 2011 J. Neurochem. pmid:21496023
Duangjit S et al. Characterization and In Vitro Skin Permeation of Meloxicam-Loaded Liposomes versus Transfersomes. 2011 J Drug Deliv pmid:21490750
Fabiano A et al. Metabolomic analysis of bronchoalveolar lavage fluid in preterm infants complicated by respiratory distress syndrome: preliminary results. 2011 J. Matern. Fetal. Neonatal. Med. pmid:21781003
Yee JK et al. Organ-specific alterations in fatty acid de novo synthesis and desaturation in a rat model of programmed obesity. 2011 Lipids Health Dis pmid:21569358
Shivanand K et al. In vivo bioavailability studies of sumatriptan succinate buccal tablets. 2011 Daru pmid:22615661
Gande S and Rao Y Sustained-release effervescent floating matrix tablets of baclofen: development, optimization and in vitro-in vivo evaluation in healthy human volunteers. 2011 Daru pmid:22615658
Varshosaz J et al. Development of novel budesonide pellets based on CODES(TM) technology: In vitro/in vivo evaluation in induced colitis in rats. 2011 Daru pmid:22615647
Dey S et al. Formulation and optimization of sustained release Stavudine microspheres using response surface methodology. 2011 ISRN Pharm pmid:22389855
Prajapati ST et al. Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. 2011 ISRN Pharm pmid:22389845
Flowers MT et al. Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism. 2011 PLoS ONE pmid:21573029
González-Mira E et al. Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen. 2011 J Pharm Sci pmid:20575052
Wang GG et al. Self-assembled biomimetic superhydrophobic CaCO3 coating inspired from fouling mineralization in geothermal water. 2011 Langmuir pmid:21919516
Asahi H et al. Plasmodium falciparum: differing effects of non-esterified fatty acids and phospholipids on intraerythrocytic growth in serum-free medium. 2011 Exp. Parasitol. pmid:21095186
Lin Y et al. Nucleating effect of calcium stearate coated CaCO(3) nanoparticles on polypropylene. 2011 J Colloid Interface Sci pmid:21122873
MacDonald AM et al. A modified supported bilayer/diblock polymer--working towards a tunable coating for capillary electrophoresis. 2011 J Chromatogr A pmid:21122870
Liu X et al. Synthesis of high quality and stability CdS quantum dots with overlapped nucleation-growth process in large scale. 2011 J Colloid Interface Sci pmid:21040929
Tamilvanan S et al. In vitro and in vivo evaluation of hydrophilic and hydrophobic polymers-based nicorandil-loaded peroral tablet compared with its once-daily commercial sustained-release tablet. 2011 Drug Dev Ind Pharm pmid:20923389
Gremos S et al. Direct enzymatic acylation of cellulose pretreated in BMIMCl ionic liquid. 2011 Bioresour. Technol. pmid:20888759
Peng Q et al. A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. 2011 Microb. Cell Fact. pmid:22067554
Yu WL et al. Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. 2011 Microb. Cell Fact. pmid:22047615
Andaloussi SE et al. Application of PepFect peptides for the delivery of splice-correcting oligonucleotides. 2011 Methods Mol. Biol. pmid:21053143
Yu DG et al. Coaxial electrospinning with organic solvent for controlling the size of self-assembled nanoparticles. 2011 Chem. Commun. (Camb.) pmid:21107459
Das SC et al. Use of surface energy distributions by inverse gas chromatography to understand mechanofusion processing and functionality of lactose coated with magnesium stearate. 2011 Eur J Pharm Sci pmid:21621612
Laverroux S et al. Isomerization of vaccenic acid to cis and trans C18:1 isomers during biohydrogenation by rumen microbes. 2011 Lipids pmid:21706384
Sekharan TR et al. Formulation and Evaluation of Hydroxypropyl Methylcellulose-based Controlled Release Matrix Tablets for Theophylline. 2011 Indian J Pharm Sci pmid:22707833
Lan DM et al. A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. 2011 Int J Mol Sci pmid:21747717