stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Metabolic Syndrome D024821 44 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Fatty Liver D005234 48 associated lipids
Thrombosis D013927 49 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Reperfusion Injury D015427 65 associated lipids
Neuroblastoma D009447 66 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
TINOCO J et al. LIVER LIPIDS OF CHOLINE-DEFICIENT RATS. 1965 Biochem. J. pmid:14345885
SRIDHARA S and BHAT JV FURTHER INVESTIGATIONS OF THE INCORPORATION OF (1-14C)ACETATE INTO THE LIPIDS OF THE SILKWORM BOMBYX MORI L. 1965 Biochem. J. pmid:14340061
BOUCROT P and CLEMENT J [SUPPLY OF ENDOGENOUS FATTY ACIDS IN RAT LYMPH FOLLOWING ADMINISTRATION OF A MEAL CONTAINING MIXED C14-STEARIC: H3-OLEIC TRIGLYCERIDES]. 1965 C. R. Hebd. Seances Acad. Sci. pmid:14341956
ROOTS BI and JOHNSTON PV LIPIDS OF ISOLATED NEURONS. 1965 Biochem. J. pmid:14342249
KANFER J OBSERVATIONS ON CEREBROSIDE METABOLISM IN VIVO. 1965 J. Biol. Chem. pmid:14275111
KEITEL HG and CHU E PREMATURE INFANT FEEDING. I. THE CLINICAL USEFULNESS OF CALORIC CONCENTRATION OF FORMULAS, OF EARLY VERSUS LATE FEEDINGS AND OF LOW STEARIC ACID CONTENT FORMULAS. 1965 Pediatr. Clin. North Am. pmid:14276882
KORN ED et al. SYNTHESIS OF UNSATURATED FATTY ACIDS IN THE SLIME MOLD PHYSARUM POLYCEPHALUM AND THE ZOOFLAGELLATES LEISHMANIA TARENTOLAE, TRYPANOSOMA LEWISI, AND CRITHIDIA SP.: A COMPARATIVE STUDY. 1965 J. Lipid Res. pmid:14280472
BACHUR NR et al. FATTY ACID AMIDES OF ETHANOLAMINE IN MAMMALIAN TISSUES. 1965 J. Biol. Chem. pmid:14284696
HANSEN HJ et al. THE EFFECT OF WHOLE-BODY X-IRRADIATION ON THE SYNTHESIS OF INDIVIDUAL FATTY ACIDS IN LIVER SLICES FROM NORMAL AND FASTED RATS. 1965 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:14309652
LAMBREMONT EN BIOSYNTHESIS OF FATTY ACIDS IN ASEPTICALLY REARED INSECTS. 1965 Comp. Biochem. Physiol. pmid:14314981