| MeSH term | MeSH ID | Detail |
|---|---|---|
| Otitis Media | D010033 | 12 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Pneumoconiosis | D011009 | 3 associated lipids |
| Eczema, Dyshidrotic | D011146 | 1 associated lipids |
| Prostatic Diseases | D011469 | 4 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Relapsing Fever | D012061 | 3 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Salivary Duct Calculi | D012465 | 2 associated lipids |
| Seizures | D012640 | 87 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rosenthal MD and Whitehurst MC | Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. | 1983 | Biochim. Biophys. Acta | pmid:6615875 |
| Emken EA et al. | Influence of linoleic acid on desaturation and uptake of deuterium-labeled palmitic and stearic acids in humans. | 1993 | Biochim. Biophys. Acta | pmid:8399342 |
| Bieri VG and Wallach DF | Variations of lipid-protein interactions in erythrocyte ghosts as a function of temperature and pH in physiological and non-physiological ranges. A study using a paramagnetic quenching of protein fluorescence by nitroxide lipid analogues. | 1975 | Biochim. Biophys. Acta | pmid:241415 |
| Wisniewska A et al. | Depth dependence of the perturbing effect of placing a bulky group (oxazolidine ring spin labels) in the membrane on the membrane phase transition. | 1996 | Biochim. Biophys. Acta | pmid:8611609 |
| Kaya K and Kusumi T | Isolation and structural characterization of a diacyltaurolipid in cells of Tetrahymena mimbres. | 1988 | Biochim. Biophys. Acta | pmid:3132980 |
| Kogure K et al. | Effect of dicetylphosphate or stearic acid on spontaneous transfer of protein from influenza virus-infected cells to dimyristoylphosphatidylcholine liposomes. | 1997 | Biochim. Biophys. Acta | pmid:9370255 |
| Watanabe S and Sato T | Effects of free fatty acids on the binding of bovine and human serum albumin with steroid hormones. | 1996 | Biochim. Biophys. Acta | pmid:8620023 |
| Stein Y et al. | Intralysosomal hydrolysis of cholesterol esters of varying fatty acid composition in cultured human skin fibroblasts. | 1978 | Biochim. Biophys. Acta | pmid:698242 |
| Goto M et al. | Evidence for a correlation between swimming velocity and membrane fluidity of Tetrahymena cells. | 1982 | Biochim. Biophys. Acta | pmid:6818990 |
| Bonini de Romanelli IC et al. | Phosphatidic acid, phosphatidylinositol, phosphatidylserine and cardiolipin in the course of early embryonic development. Fatty acid composition and content in whole toad embryos and in mitochondrial fractions. | 1981 | Biochim. Biophys. Acta | pmid:6791698 |
| Murakami C et al. | A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid. | 2003 | Biochim. Biophys. Acta | pmid:12535613 |
| Chester DW et al. | The influence of saturated fatty acid modulation of bilayer physical state on cellular and membrane structure and function. | 1986 | Biochim. Biophys. Acta | pmid:3741857 |
| Kordyukova LV et al. | Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. | 2011 | Biochim. Biophys. Acta | pmid:21420932 |
| Giacobino JP and Chmelar M | The role of chain elongation systems in the supplying of fatty acids to the adipocyte membrane lipids. | 1977 | Biochim. Biophys. Acta | pmid:861235 |
| Arukuusk P et al. | New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids. | 2013 | Biochim. Biophys. Acta | pmid:23357356 |
| AlegrÃa AE et al. | Semiquinones derived from anthraquinone-containing antitumor drugs can partition into phosphatidylcholine bilayers. | 1990 | Biochim. Biophys. Acta | pmid:2166575 |
| Kitagawa S et al. | Inhibitory mechanism of cis-polyunsaturated fatty acids on platelet aggregation: the relation with their effects on Ca2+ mobilization, cyclic AMP levels and membrane fluidity. | 1990 | Biochim. Biophys. Acta | pmid:2166588 |
| Anel A et al. | Fatty acid metabolism in human lymphocytes. II. Activation of fatty acid desaturase-elongase systems during blastic transformation. | 1990 | Biochim. Biophys. Acta | pmid:2114179 |
| Rich MR | Conformational analysis of arachidonic and related fatty acids using molecular dynamics simulations. | 1993 | Biochim. Biophys. Acta | pmid:8329458 |
| Katz AM et al. | Fatty acid effects on calcium influx and efflux in sarcoplasmic reticulum vesicles from rabbit skeletal muscle. | 1982 | Biochim. Biophys. Acta | pmid:7074105 |
| IKAWA M | OCCURRENCE AND IDENTIFICATION OF CIS-VACCENIC ACID IN LEUCONOSTOC MESENTEROIDES. | 1964 | Biochim. Biophys. Acta | pmid:14181302 |
| BURTON RM and GIBBONS JM | LIPID COMPOSITION OF A RAT-BRAIN SYNAPTIC-VESICLE FRACTION. | 1964 | Biochim. Biophys. Acta | pmid:14181307 |
| ROWE CE | THE OCCURRENCE AND METABOLISM IN VITRO OF UNESTERIFIED FATTY ACID IN MOUSE BRAIN. | 1964 | Biochim. Biophys. Acta | pmid:14230816 |
| KELLERMAN GM and JOLLOW DJ | CONVERSION OF STEARIC ACID INTO OLEIC ACID IN ADIPOSE TISSUE. | 1964 | Biochim. Biophys. Acta | pmid:14230826 |
| Husebye ES and Flatmark T | Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. | 1987 | Biochim. Biophys. Acta | pmid:3607074 |
| Kedryna T et al. | Pyruvate kinase from cytosolic fractions of the Ehrlich ascites tumour, normal mouse liver and skeletal muscle. | 1990 | Biochim. Biophys. Acta | pmid:2354196 |
| Wang Y et al. | Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue. | 2017 | Biochim. Biophys. Acta | pmid:28526351 |
| Morimoto K and Kanoh H | The role of the de novo synthetic pathway in forming molecular species of phospholipids in resting lymphocytes from human tonsils. | 1980 | Biochim. Biophys. Acta | pmid:7353023 |
| Morandi S et al. | Association of sugar-based carboranes with cationic liposomes: an electron spin resonance and light scattering study. | 2004 | Biochim. Biophys. Acta | pmid:15238258 |
| Shires SE et al. | Effects of linoleic acid and mitogenic stimulation on the fatty acid composition of human lymphocytes. | 1989 | Biochim. Biophys. Acta | pmid:2493807 |
| Höltje M et al. | Molecular dynamics simulations of stratum corneum lipid models: fatty acids and cholesterol. | 2001 | Biochim. Biophys. Acta | pmid:11248214 |
| Ellingson JS and Seenaiah B | The selective use of stearoyl-polyunsaturated molecular species of phosphatidylcholine and phosphatidylethanolamine for the synthesis of phosphatidylserine. | 1994 | Biochim. Biophys. Acta | pmid:8011673 |
| Sivarajan M et al. | Regulation of intracellular arachidonate in normal and stressed endothelial cells. | 1984 | Biochim. Biophys. Acta | pmid:6433983 |
| Privat JP et al. | Incorporation of spin-labeled fatty acids into bovine brain clathrin coated vesicles. | 1990 | Biochim. Biophys. Acta | pmid:2158352 |
| ELSBACH P | COMPARISON OF UPTAKE OF PALMITIC, STEARIC, OLEIC AND LINOLEIC ACID BY POLYMORPHONUCLEAR LEUKOCYTES. | 1964 | Biochim. Biophys. Acta | pmid:14124760 |
| Watanabe L et al. | Structural insights for fatty acid binding in a Lys49-phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid. | 2005 | Biochimie | pmid:15760708 |
| Pollet S et al. | [Substrates and products of fatty acid elongation in mouse brain microsomes]. | 1975 | Biochimie | pmid:1222143 |
| Zhu S et al. | Lysosomal delivery of a lipophilic gemcitabine prodrug using novel acid-sensitive micelles improved its antitumor activity. | 2012 | Bioconjug. Chem. | pmid:22471294 |
| Zhang W et al. | Stearylated antimicrobial peptide melittin and its retro isomer for efficient gene transfection. | 2013 | Bioconjug. Chem. | pmid:24107137 |
| Futaki S et al. | Stearylated arginine-rich peptides: a new class of transfection systems. | 2001 Nov-Dec | Bioconjug. Chem. | pmid:11716693 |
| Fabianowski W et al. | Integrated circuits protection with the Langmuir-Blodgett Films. | 2005 | Bioelectrochemistry | pmid:15833702 |
| Petelska AD et al. | Interfacial tension of the lipid membrane formed from lipid-fatty acid and lipid-amine systems. | 2007 | Bioelectrochemistry | pmid:16713376 |
| Staritsyn SN et al. | [Mixed monolayers of amphiphile-modified nucleic bases and diynoic acids. I. Phase states at air-water interface and in Langmuir-Blodgett films]. | 2004 Jul-Aug | Biofizika | pmid:15458246 |
| Saatov TS et al. | [Content, intensity of exchange, and metabolic interaction of phospholipids and glycolipids in various tissues in experimental diabetes]. | 1983 | Biokhimiia | pmid:6671113 |
| Moore IM et al. | Methotrexate-induced alterations in beta-oxidation correlate with cognitive abilities in children with acute lymphoblastic leukemia. | 2008 | Biol Res Nurs | pmid:18398226 |
| Droke EA et al. | Fatty acids alter monolayer integrity, paracellular transport, and iron uptake and transport in Caco-2 cells. | 2003 | Biol Trace Elem Res | pmid:14665727 |
| Finley JW and Davis CD | Manganese absorption and retention in rats is affected by the type of dietary fat. | 2001 | Biol Trace Elem Res | pmid:11697763 |
| Miersch O and Wasternack C | Octadecanoid and jasmonate signaling in tomato (Lycopersicon esculentum Mill.) leaves: endogenous jasmonates do not induce jasmonate biosynthesis. | 2000 | Biol. Chem. | pmid:11030429 |
| Rüdiger M et al. | Are biochemical parameters of lung maturation from gastric, tracheal, and pharyngeal aspirates comparable? | 1998 | Biol. Neonate | pmid:9618052 |
| Ishitsuka Y et al. | Effects of bolus injection of soybean-based fat emulsion and fatty acids on pulmonary gas exchange function. | 2009 | Biol. Pharm. Bull. | pmid:19252304 |