stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Otitis Media D010033 12 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Pneumoconiosis D011009 3 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Prostatic Diseases D011469 4 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Relapsing Fever D012061 3 associated lipids
Rosacea D012393 13 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Arai T and Hosoi Y [Determination of magnesium stearate in pharmaceutical preparations using derivatization with 2-nitrophenylhydrazine and HPLC]. 2005 Yakugaku Zasshi pmid:15738629
Iwao Y [Efficient Pharmaceutical Formulation Designs and Their Development Using Mathematical and Statistical Analysis]. 2015 Yakugaku Zasshi pmid:26423868
Miyake Y et al. [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. 1973 Yakugaku Zasshi pmid:4797567
Miyake Y et al. [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. 1972 Yakugaku Zasshi pmid:4675495
El Semary NA The antimicrobial profile of extracts of a Phormidium-like cyanobacterium changes with phosphate levels. 2012 World J. Microbiol. Biotechnol. pmid:22806854
Chen JL et al. Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry. 2010 World J. Gastroenterol. pmid:21155010
Liu Z et al. Changes in the electron paramagnetic resonance spectra of albumin-associated spin-labeled stearic acid as a diagnostic parameter of colorectal cancer. 2013 World J Surg Oncol pmid:24025321
Miranda LA et al. Performance of UASB and DAEB reactors in the anaerobic digestion of synthetic wastewater containing sodium oleate and sodium stereate. 2006 Water Sci. Technol. pmid:16939093
Alves MM et al. Effects of lipids and oleic acid on biomass development in anaerobic fixed-bed reactors. Part II: Oleic acid toxicity and biodegradability. 2001 Water Res. pmid:11257881
Lalman JA and Bagley DM Anaerobic degradation and methanogenic inhibitory effects of oleic and stearic acids. 2001 Water Res. pmid:11471698
Kosukhin AB et al. [The mechanism of formation of spectrum of nonesterified fatty acids in biological fluids of rabbits with alimentary hypercholesterolemia]. 1989 Mar-Apr Vopr. Med. Khim. pmid:2741412
Zaridze DG et al. [Fatty acid composition of phospholipids of erythrocyte membranes and risk of breast cancer]. 1990 Vopr Onkol pmid:2126901
Bridges CD et al. Visual cycle in the mammalian eye. Retinoid-binding proteins and the distribution of 11-cis retinoids. 1984 Vision Res. pmid:6543481
MacDonald RC et al. Inhibition of sendai virus-induced hemolysis by long chain fatty acids. 1984 Virology pmid:6324464
Nozawa CM and Apostolov K Increase in the saturation of C18 fatty acids induced by coxsackie B6 virus in Vero cells. 1982 Virology pmid:6285601
Kordyukova LV et al. Site-specific attachment of palmitate or stearate to cytoplasmic versus transmembrane cysteines is a common feature of viral spike proteins. 2010 Virology pmid:20006369
Lavergne SN et al. Potential cutaneous hypersensitivity reaction to an inactive ingredient of thyroid hormone supplements in a dog. 2016 Vet. Dermatol. pmid:26748887
Veit M and Siche S S-acylation of influenza virus proteins: Are enzymes for fatty acid attachment promising drug targets? 2015 Vaccine pmid:26387429
Colmano G et al. Activated silver coatings for surgical implants. 1979 Va Med pmid:316624
Mizukoshi Y et al. Preparation of platinum nanoparticles by sonochemical reduction of the Pt(IV) ions: role of surfactants. 2001 Ultrason Sonochem pmid:11105315