stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Stanisz B et al. Effect of pharmaceutical excipients on the stability of angiotensin-converting enzyme inhibitors in their solid dosage formulations. 2013 Drug Dev Ind Pharm pmid:22348774
Vitturi DA et al. Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. 2013 J. Biol. Chem. pmid:23878198
Saeedi Vahdat A et al. Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets. 2013 Int J Pharm pmid:23820132
Li L et al. Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film. 2013 Int J Pharm pmid:23624081
Neutsch L et al. UPEC biomimickry at the urothelial barrier: lectin-functionalized PLGA microparticles for improved intravesical chemotherapy. 2013 Int J Pharm pmid:23628404
Emken E Human studies using isotope labeled fatty acids: answered and unanswered questions. 2013 J Oleo Sci pmid:23648399
Zhou X et al. The effect of saturated fatty acids on methanogenesis and cell viability of Methanobrevibacter ruminantium. 2013 Archaea pmid:23710130
Silberstein T et al. Saturated fatty acid composition of human milk in Israel: a comparison between Jewish and Bedouin women. 2013 Isr. Med. Assoc. J. pmid:23781748
Otsuka Y et al. Effects of polymorphic transformation on pharmaceutical properties of direct compressed tablets containing theophylline anhydrate bulk powder under high humidity. 2013 Colloids Surf B Biointerfaces pmid:23178204
Azordegan N et al. Carcinogenesis alters fatty acid profile in breast tissue. 2013 Mol. Cell. Biochem. pmid:23180247
Delbecq F et al. N-stearoyl amino acid derivatives: potent biomimetic hydro/organogelators as templates for preparation of gold nanoparticles. 2013 J Colloid Interface Sci pmid:23089597
Barber E et al. Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:24012207
Cunha TA et al. Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. 2013 AAPS PharmSciTech pmid:23897034
Jaumot J et al. Blending process modeling and control by multivariate curve resolution. 2013 Talanta pmid:24209372
Høstmark AT et al. Increased serum triglycerides and reduced HDL cholesterol in male rats after intake of ammonium chloride for 3 weeks. 2013 Lipids Health Dis pmid:23800210
Saroja C and Lakshmi PK Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design. 2013 Acta Pharm pmid:23482314
Pethrick RA and Song M Dielectric studies of amylose, amylopectin and amylose-stearic acid complexes. 2013 Carbohydr Polym pmid:23399185
Subbaramaiah K et al. Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice. 2013 Cancer Prev Res (Phila) pmid:23880231
Tammaro A et al. Magnesium stearate: an underestimated allergen. 2012 Oct-Dec J. Biol. Regul. Homeost. Agents pmid:23241129
Hentzschel CM et al. Comparison of traditional and novel tableting excipients: physical and compaction properties. 2012 Nov-Dec Pharm Dev Technol pmid:21740091
Khan FN and Dehghan MH Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. 2012 Jan-Mar Sci Pharm pmid:22396916
Pujeri SS et al. Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. 2012 Jan-Mar Sci Pharm pmid:22396908
Samanta AK et al. Cone milling of compacted flakes: process parameter selection by adopting the minimal fines approach. 2012 Int J Pharm pmid:22001841
Tay T et al. Dissolution of a poorly water-soluble drug dry coated with magnesium and sodium stearate. 2012 Eur J Pharm Biopharm pmid:22036990
Abe H and Otsuka M Effects of lubricant-mixing time on prolongation of dissolution time and its prediction by measuring near infrared spectra from tablets. 2012 Drug Dev Ind Pharm pmid:21954869
Milicic A et al. Small cationic DDA:TDB liposomes as protein vaccine adjuvants obviate the need for TLR agonists in inducing cellular and humoral responses. 2012 PLoS ONE pmid:22470545
Mason P et al. SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids. 2012 PLoS ONE pmid:22457791
Olivieri C et al. Phylogenetic position of a copper age sheep (Ovis aries) mitochondrial DNA. 2012 PLoS ONE pmid:22457789
Casiraghi A et al. The influence of the polar head and the hydrophobic chain on the skin penetration enhancement effect of poly(ethylene glycol) derivatives. 2012 AAPS PharmSciTech pmid:22232021
Wei CC and Ge ZQ Influence of electrolyte and poloxamer 188 on the aggregation kinetics of solid lipid nanoparticles (SLNs). 2012 Drug Dev Ind Pharm pmid:22181005
Singh AV and Nath LK Evaluation of acetylated moth bean starch as a carrier for controlled drug delivery. 2012 Int. J. Biol. Macromol. pmid:22210486
Basseri S and Austin RC Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential. 2012 Biochem Res Int pmid:22195283
Seeliger JC et al. Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. 2012 J. Biol. Chem. pmid:22194604
Hao J et al. Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design. 2012 Eur J Pharm Sci pmid:22820033
Kakisaka K et al. Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:21995961
Kim DH et al. Fabrication of pseudo-ceramide-based lipid microparticles for recovery of skin barrier function. 2012 Colloids Surf B Biointerfaces pmid:22361356
Honkanen AM et al. Characterization of the disappearance and formation of biohydrogenation intermediates during incubations of linoleic acid with rumen fluid in vitro. 2012 J. Dairy Sci. pmid:22365221
Kushner J Incorporating Turbula mixers into a blending scale-up model for evaluating the effect of magnesium stearate on tablet tensile strength and bulk specific volume. 2012 Int J Pharm pmid:22405966
Matsui H et al. Stearoyl-CoA desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes. 2012 PLoS ONE pmid:22413010
Trupp M et al. Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. 2012 PLoS ONE pmid:22808006
McNamee CE et al. Effect of the degree of dissociation of molecules in a monolayer at an air/water interface on the force between the monolayer and a like-charged particle in the subphase. 2012 J Phys Chem B pmid:23092192
Akinsete JA et al. Consumption of high ω-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice. 2012 Carcinogenesis pmid:22045025
Baldwin AC et al. A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22436701
Weiss VM et al. Poly(glycerol adipate)-fatty acid esters as versatile nanocarriers: From nanocubes over ellipsoids to nanospheres. 2012 J Control Release pmid:21971295
Tuli RA et al. Polycaprolactone microspheres as carriers for dry powder inhalers: effect of surface coating on aerosolization of salbutamol sulfate. 2012 J Pharm Sci pmid:21956254
Shuhendler AJ et al. Thermally-triggered 'off-on-off' response of gadolinium-hydrogel-lipid hybrid nanoparticles defines a customizable temperature window for non-invasive magnetic resonance imaging thermometry. 2012 J Control Release pmid:21939700
Nesarikar VV et al. Instrumented roll technology for the design space development of roller compaction process. 2012 Int J Pharm pmid:22286023
Eili M et al. Degradability enhancement of poly(lactic acid) by stearate-Zn(3)Al LDH nanolayers. 2012 Int J Mol Sci pmid:22942682
Hayashi Y et al. Latent structure analysis of the process variables and pharmaceutical responses of an orally disintegrating tablet. 2012 Chem. Pharm. Bull. pmid:22878814
Tamokou Jde D et al. Antioxidant and antimicrobial activities of ethyl acetate extract, fractions and compounds from stem bark of Albizia adianthifolia (Mimosoideae). 2012 BMC Complement Altern Med pmid:22809287