stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

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What functions are associated with stearic acid?


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What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

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What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Comai K et al. Analyses of renal medullary lipid droplets from normal, hydronephrotic, and indomethacin treated rabbits. 1975 Lipids pmid:1177669
Thompson GE and Darling KF The hepatic uptake of individual free fatty acids in sheep during noradrenaline infusion. 1975 Res. Vet. Sci. pmid:1144925
York P Application of powder failure testing equipment in assessing effect on glidants on flowability of cohesive pharmaceutical powders. 1975 J Pharm Sci pmid:1151687
Weaire PJ and Kekwick RG The fractionation of the fatty acid synthetase activities of avocado mesocarp plastids. 1975 Biochem. J. pmid:1156381
Janicki RS et al. Comparison of erythromycin ethyl succinate, stearate and estolate treatments of group A streptococcal infections of the upper respiratory tract. 1975 Clin Pediatr (Phila) pmid:1104241
Männistö P et al. Absorption of erythromycin. A cross-over study in healthy volunteers. 1975 Arzneimittelforschung pmid:1106445
Anderson RR et al. Composition of cottontail rabbit milk from stomachs of young and directly from gland. 1975 J. Dairy Sci. pmid:1184805
Gaginella TS et al. Actions of ricinoleic acid and structurally related fatty acids on the gastrointestinal tract. II. Effects on water and electrolyte absorption in vitro. 1975 J. Pharmacol. Exp. Ther. pmid:1185605
Smith RW and Walsh A Composition of liver lipids of the rat during pregnancy and lactation. 1975 Lipids pmid:1186452
Schmidt P et al. [Animal experiments on barium stearate toxicity]. 1975 Z Gesamte Hyg pmid:1189478
Sato M et al. [Clinical studies on OE-7 chiefly in the treatment of acute respiratory infections (author's transl)]. 1975 Jpn J Antibiot pmid:1195513
Harwood JL and James AT Metabolism of trans-3-hexadecenoic acid in broad bean. 1975 Eur. J. Biochem. pmid:1126340
Kuksis A et al. Distribution of newly formed fatty acids among glycerolipids of isolated perfused rat liver. 1975 Can. J. Biochem. pmid:1139394
Kuksis A et al. Distribution of newly formed palmitate and stearate among molecular species of choline and ethanolamine phosphatides. 1975 Can. J. Biochem. pmid:1139395
Parkes JG and Thompson W Phosphatidylethanolamine in liver mitochondria and endoplasmic reticulum: molecular species distribution and turnover. 1975 Can. J. Biochem. pmid:1139407
Tola S Occupational lead exposure in Finland. IV. The polyvinyl chloride plastic industry. 1975 Scand J Work Environ Health pmid:1228897
Iot T et al. Synthesis of a new phosphatidylserine spin-label and calcium-induced lateral phase separation in phosphatidylserine-phosphatidylcholine membranes. 1975 Biochemistry pmid:167814
Thompson W and MacDonald G Isolation and characterization of cytidine diphosphate diglyceride from beef liver. 1975 J. Biol. Chem. pmid:169258
Morrisett JD et al. Multiple thermotropic phase transitions in Escherichia coli membranes and membrane lipids. A comparison of results obtained by nitroxyl stearate paramagnetic resonance, pyrene excimer fluorescence, and enzyme activity measurements. 1975 J. Biol. Chem. pmid:169264
Asker AF et al. Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 5: Effects of lubricants and flow conditions. 1975 Pharmazie pmid:169527