stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

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What functions are associated with stearic acid?


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What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

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What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Mastronicolis SK et al. Diversity of the polar lipids of the food-borne pathogen Listeria monocytogenes. 1996 Lipids pmid:8784744
Reverey H et al. Differential fatty acid selection during biosynthetic S-acylation of a transmembrane protein (HEF) and other proteins in insect cells (Sf9) and in mammalian cells (CV1). 1996 J. Biol. Chem. pmid:8798573
Kirsch AJ et al. Effects of diode laser welding with dye-enhanced glue on tensile strength of sutures commonly used in urology. 1996 Lasers Surg Med pmid:8833285
Pai T and Yeh YY Stearic acid unlike shorter-chain saturated fatty acids is poorly utilized for triacylglycerol synthesis and beta-oxidation in cultured rat hepatocytes. 1996 Lipids pmid:8835403
Gotoh N et al. Inhibition of oxidation of low density lipoprotein by vitamin E and related compounds. 1996 Free Radic. Res. pmid:8845913
Shetty HU et al. Identification of two molecular species of rat brain phosphatidylcholine that rapidly incorporate and turn over arachidonic acid in vivo. 1996 J. Neurochem. pmid:8858956
Uchida T et al. Microencapsulation of ovalbumin in poly(lactide-co-glycolide) by an oil-in-oil (o/o) solvent evaporation method. 1996 Sep-Oct J Microencapsul pmid:8864988
Murkovic M et al. Variability of fatty acid content in pumpkin seeds (Cucurbita pepo L.). 1996 Z Lebensm Unters Forsch pmid:8873459
Wargo DJ and Drennen JK Near-infrared spectroscopic characterization of pharmaceutical powder blends. 1996 J Pharm Biomed Anal pmid:8877847
Peck MD et al. Fatty acid unsaturation increases expression and capping of murine lymphocyte CD44 and CD45. 1996 Nutrition pmid:8878171